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The map label for this gene is yecD [H]

Identifier: 182679143

GI number: 182679143

Start: 2489998

End: 2490570

Strand: Direct

Name: yecD [H]

Synonym: Bind_2180

Alternate gene names: 182679143

Gene position: 2489998-2490570 (Clockwise)

Preceding gene: 182679141

Following gene: 182679144

Centisome position: 59.71

GC content: 56.37

Gene sequence:

>573_bases
ATGTCCGATCTCGATCCCCGCACAACGGCACTTGTCCTGATTGATCTTCAAAATGGCATTGCCAGCATGCCCCTCGCGCC
ACGCTCAGGTCCAGAAACCGTAGCGGTGGGAAAGACACTCGCCGGACGCTTCCGAGCGGCTGGCGCTTTGGTGGTCCTCG
TTCATGTTGGATTTGCGGAGGATTTCGCCGATGCGCCAAGCCAGCTTGTGGACCAGCCCTTTGCTCTCCCCGAAGGCGGC
CTGCCAGCCGGTTGGACGGAGTTCGTTGAGGGTCTCGCCCAACCAAAAGATATCATCATTACCAAACGCCAATGGGGCGC
CTTTCATGGCACCGAGCTCGATTTGCAGCTTCGGCGTCGAGGGATACGCACGATTGTCCTTGGCGGGATTGCGACTAATT
TTGGTGTCGAATCGACGGCGCGTCAGGCGTGGGAACATGGATATGAAGTGCTTCTCGCCGAGGATGCGTGTAGCTCTTTT
TCGAAAGACCTTCACACCATGGCGATCCAGTACATTTTTCCCCGCATTACCCACGTGATCACAAGCACTGCGATCGGTTT
TGCAACACACTAA

Upstream 100 bases:

>100_bases
TCTCATTTGCGAGTCTATCCTCGCATATCATTCCTCAAGTCTCCCGTCACCTTTTCCCAAAAGGTGACACATCTTCACCG
TTCTCCGGAAAGCGACTTGA

Downstream 100 bases:

>100_bases
GATAGCGCACCTATGCTCATTCGGATGATACCGCTGCGTCTGTTATCACTCCACAATCAAACGGCCGGCATGCAGTGGAG
CATCCTGCTTGCCCTCTCGA

Product: isochorismatase hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSDLDPRTTALVLIDLQNGIASMPLAPRSGPETVAVGKTLAGRFRAAGALVVLVHVGFAEDFADAPSQLVDQPFALPEGG
LPAGWTEFVEGLAQPKDIIITKRQWGAFHGTELDLQLRRRGIRTIVLGGIATNFGVESTARQAWEHGYEVLLAEDACSSF
SKDLHTMAIQYIFPRITHVITSTAIGFATH

Sequences:

>Translated_190_residues
MSDLDPRTTALVLIDLQNGIASMPLAPRSGPETVAVGKTLAGRFRAAGALVVLVHVGFAEDFADAPSQLVDQPFALPEGG
LPAGWTEFVEGLAQPKDIIITKRQWGAFHGTELDLQLRRRGIRTIVLGGIATNFGVESTARQAWEHGYEVLLAEDACSSF
SKDLHTMAIQYIFPRITHVITSTAIGFATH
>Mature_189_residues
SDLDPRTTALVLIDLQNGIASMPLAPRSGPETVAVGKTLAGRFRAAGALVVLVHVGFAEDFADAPSQLVDQPFALPEGGL
PAGWTEFVEGLAQPKDIIITKRQWGAFHGTELDLQLRRRGIRTIVLGGIATNFGVESTARQAWEHGYEVLLAEDACSSFS
KDLHTMAIQYIFPRITHVITSTAIGFATH

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

Organism=Escherichia coli, GI87081992, Length=180, Percent_Identity=52.2222222222222, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI87081820, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 20464; Mature: 20332

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLDPRTTALVLIDLQNGIASMPLAPRSGPETVAVGKTLAGRFRAAGALVVLVHVGFAE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCHH
DFADAPSQLVDQPFALPEGGLPAGWTEFVEGLAQPKDIIITKRQWGAFHGTELDLQLRRR
HHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHC
GIRTIVLGGIATNFGVESTARQAWEHGYEVLLAEDACSSFSKDLHTMAIQYIFPRITHVI
CCCEEEECCHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSTAIGFATH
HHHHHHCCCC
>Mature Secondary Structure 
SDLDPRTTALVLIDLQNGIASMPLAPRSGPETVAVGKTLAGRFRAAGALVVLVHVGFAE
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCHH
DFADAPSQLVDQPFALPEGGLPAGWTEFVEGLAQPKDIIITKRQWGAFHGTELDLQLRRR
HHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHC
GIRTIVLGGIATNFGVESTARQAWEHGYEVLLAEDACSSFSKDLHTMAIQYIFPRITHVI
CCCEEEECCHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSTAIGFATH
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]