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The map label for this gene is srpC [H]

Identifier: 182678989

GI number: 182678989

Start: 2313243

End: 2314820

Strand: Reverse

Name: srpC [H]

Synonym: Bind_2024

Alternate gene names: 182678989

Gene position: 2314820-2313243 (Counterclockwise)

Preceding gene: 182678990

Following gene: 182678987

Centisome position: 55.51

GC content: 57.73

Gene sequence:

>1578_bases
ATGGCGGATAGAAAAAGCCTCACTCCGGCAATATTTGCCATTGTCTCTCTCAGCACTGGCCTCGGTGGTTGTCTCTCTGT
CGGTCCCGATTATGTGGGGCCGGACCCGATGCTTCCCGCGAAGTCCTTTTACGGGCCACCGGAACCGGCAGCGGCGGTCG
CGGCCTTGCCATCGCAAGGACCGGCCAAGGGGCCGGTGTCGCCAGTCGATCCTCTCTGGTGGCGCACGTTCCGAGACCCC
ACTTTGACGTCGCTTGTACAAAGAGCAGCGGGTGCCAATCTGGACGTTCGTACAGCCTCGATGCGCTTGGCACAGAGTCG
CTTTGAACGTGGTGTTACGGCTGCGGCCGCATTGCCGACCGGCAATGGCAATGCAAGTTATAATCGTCAGCAAATCAGTA
ATCAGGGTGTTGTCACTCTGGTTAATCCGCTCGTCCAACAACTCGGCGTCGGTGCGTTTACCGTGCCGCCAATCAATGTC
TGGTCGCCGACATTCGATGCATCCTGGGAACTCGATATCTGGGGCCATGTACGCCGGCAGATTGAAGCAGCAGATGCGCA
AATGGATGCCGCCGAAGAACAACGCCGCGCCATGCTTGTCTCGACCATGGCGGAACTCGCGCGTGACTACATTCAATTGC
GCGGGGTTCAGGCGCAGATTGGCATCCTCAAAGACAATATCGTGAGTTCCGAGGATATTCTGAAACTGACCCGGACCCGG
GCCGAGAAAGGCATGACAACAGGCCTTGATGTCGAGAATGCTGCCGCACAGGTCGAAAGCGAGAAAGCGCAATTGCCGAG
CCTTGAGGATCAGCAAATAGAGCTCATCAATGCTCTAAGCCTATTGCTGGATAGCCCCCCTGGGGCCCTCAATGATGAGC
TCATCAAATCGAAGCCCATCCCTCCCGTGCCCCCACAGGTTCCGCTGGGCATTCCTTCCGAACTCGCTCGCCGGCGCCCG
GATATTCGGCAGGCCGAAGCGCAACTCCATTCAGCGACCGCCAATATTGGCGTCGCGGTGGCGGAATTCTATCCAACTGT
CAAACTGAATGGCAGCGTGGGTGCCAATGCCCTCGATTTCAAGAATTTGTGGAAGCCGAGTGCATTGCAATATAATTTTG
GGCCGAGCTTTGCTGTTCCGCTCTTCGACGGCGGCCGGTTGAAAGCGACTCTGCACTTGCGTGAGGCTCAGCAGCAGGAA
GCGGCGATCGCCTACCATAAGACCGTGCTCGGTGCCTGGCATGAGGTGGTCAATACATTGACTGCTTATCAGAAAGAGCA
GCAAAGGCGGGCGAGGCTCAACGCGCAGGTCGATCATGCGCGCCAAGTGCTTTCGCTCTCACGCACACGCTATAATACAG
GCGTCACCGATTTCATTACCGTGCTCGACGCGGAACGCACGCTTCTTGGAGCGCAGCAGCAATATGCGCAGAGCACGACC
AATGTCTCGACCGATCTCGTTGCCCTTTACAAAGCACTCGGGGGTGGCTGGGAAATGGTGTTTCCCGACAAGGATGCACC
AACTCTGGCTACGCCCGAGATGACCGCTTCGGTGGCGCCGGCTCCAGCGGCCCAATAG

Upstream 100 bases:

>100_bases
GGATAAAAGTCAGATATCATGCGTCGGATCATGGTGCCGATACATAAAACTGATAATATCGGTGATCTATACTCTGTTTC
TCGATTGGTTGCGGACTGAC

Downstream 100 bases:

>100_bases
GCTTATGATGCTGGATGTCTTGGCGCGGCGGCGCGGCGCAGCCGGTCGTTGATCGCCTCGCCGAGACCGGTTTCGGGGAT
GGGCGCCACCGCGATCGTCT

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MADRKSLTPAIFAIVSLSTGLGGCLSVGPDYVGPDPMLPAKSFYGPPEPAAAVAALPSQGPAKGPVSPVDPLWWRTFRDP
TLTSLVQRAAGANLDVRTASMRLAQSRFERGVTAAAALPTGNGNASYNRQQISNQGVVTLVNPLVQQLGVGAFTVPPINV
WSPTFDASWELDIWGHVRRQIEAADAQMDAAEEQRRAMLVSTMAELARDYIQLRGVQAQIGILKDNIVSSEDILKLTRTR
AEKGMTTGLDVENAAAQVESEKAQLPSLEDQQIELINALSLLLDSPPGALNDELIKSKPIPPVPPQVPLGIPSELARRRP
DIRQAEAQLHSATANIGVAVAEFYPTVKLNGSVGANALDFKNLWKPSALQYNFGPSFAVPLFDGGRLKATLHLREAQQQE
AAIAYHKTVLGAWHEVVNTLTAYQKEQQRRARLNAQVDHARQVLSLSRTRYNTGVTDFITVLDAERTLLGAQQQYAQSTT
NVSTDLVALYKALGGGWEMVFPDKDAPTLATPEMTASVAPAPAAQ

Sequences:

>Translated_525_residues
MADRKSLTPAIFAIVSLSTGLGGCLSVGPDYVGPDPMLPAKSFYGPPEPAAAVAALPSQGPAKGPVSPVDPLWWRTFRDP
TLTSLVQRAAGANLDVRTASMRLAQSRFERGVTAAAALPTGNGNASYNRQQISNQGVVTLVNPLVQQLGVGAFTVPPINV
WSPTFDASWELDIWGHVRRQIEAADAQMDAAEEQRRAMLVSTMAELARDYIQLRGVQAQIGILKDNIVSSEDILKLTRTR
AEKGMTTGLDVENAAAQVESEKAQLPSLEDQQIELINALSLLLDSPPGALNDELIKSKPIPPVPPQVPLGIPSELARRRP
DIRQAEAQLHSATANIGVAVAEFYPTVKLNGSVGANALDFKNLWKPSALQYNFGPSFAVPLFDGGRLKATLHLREAQQQE
AAIAYHKTVLGAWHEVVNTLTAYQKEQQRRARLNAQVDHARQVLSLSRTRYNTGVTDFITVLDAERTLLGAQQQYAQSTT
NVSTDLVALYKALGGGWEMVFPDKDAPTLATPEMTASVAPAPAAQ
>Mature_524_residues
ADRKSLTPAIFAIVSLSTGLGGCLSVGPDYVGPDPMLPAKSFYGPPEPAAAVAALPSQGPAKGPVSPVDPLWWRTFRDPT
LTSLVQRAAGANLDVRTASMRLAQSRFERGVTAAAALPTGNGNASYNRQQISNQGVVTLVNPLVQQLGVGAFTVPPINVW
SPTFDASWELDIWGHVRRQIEAADAQMDAAEEQRRAMLVSTMAELARDYIQLRGVQAQIGILKDNIVSSEDILKLTRTRA
EKGMTTGLDVENAAAQVESEKAQLPSLEDQQIELINALSLLLDSPPGALNDELIKSKPIPPVPPQVPLGIPSELARRRPD
IRQAEAQLHSATANIGVAVAEFYPTVKLNGSVGANALDFKNLWKPSALQYNFGPSFAVPLFDGGRLKATLHLREAQQQEA
AIAYHKTVLGAWHEVVNTLTAYQKEQQRRARLNAQVDHARQVLSLSRTRYNTGVTDFITVLDAERTLLGAQQQYAQSTTN
VSTDLVALYKALGGGWEMVFPDKDAPTLATPEMTASVAPAPAAQ

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=500, Percent_Identity=26, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI2367348, Length=428, Percent_Identity=23.3644859813084, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 56524; Mature: 56393

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRKSLTPAIFAIVSLSTGLGGCLSVGPDYVGPDPMLPAKSFYGPPEPAAAVAALPSQG
CCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHCCCCCC
PAKGPVSPVDPLWWRTFRDPTLTSLVQRAAGANLDVRTASMRLAQSRFERGVTAAAALPT
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEECCC
GNGNASYNRQQISNQGVVTLVNPLVQQLGVGAFTVPPINVWSPTFDASWELDIWGHVRRQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHH
IEAADAQMDAAEEQRRAMLVSTMAELARDYIQLRGVQAQIGILKDNIVSSEDILKLTRTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCHHHHHHHHHHH
AEKGMTTGLDVENAAAQVESEKAQLPSLEDQQIELINALSLLLDSPPGALNDELIKSKPI
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
PPVPPQVPLGIPSELARRRPDIRQAEAQLHSATANIGVAVAEFYPTVKLNGSVGANALDF
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCEEEEHHCCEEEECCCCCCCCCCH
KNLWKPSALQYNFGPSFAVPLFDGGRLKATLHLREAQQQEAAIAYHKTVLGAWHEVVNTL
HHCCCCCCEEECCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYQKEQQRRARLNAQVDHARQVLSLSRTRYNTGVTDFITVLDAERTLLGAQQQYAQSTT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NVSTDLVALYKALGGGWEMVFPDKDAPTLATPEMTASVAPAPAAQ
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADRKSLTPAIFAIVSLSTGLGGCLSVGPDYVGPDPMLPAKSFYGPPEPAAAVAALPSQG
CCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHCCCCCC
PAKGPVSPVDPLWWRTFRDPTLTSLVQRAAGANLDVRTASMRLAQSRFERGVTAAAALPT
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEECCC
GNGNASYNRQQISNQGVVTLVNPLVQQLGVGAFTVPPINVWSPTFDASWELDIWGHVRRQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHH
IEAADAQMDAAEEQRRAMLVSTMAELARDYIQLRGVQAQIGILKDNIVSSEDILKLTRTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCHHHHHHHHHHH
AEKGMTTGLDVENAAAQVESEKAQLPSLEDQQIELINALSLLLDSPPGALNDELIKSKPI
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
PPVPPQVPLGIPSELARRRPDIRQAEAQLHSATANIGVAVAEFYPTVKLNGSVGANALDF
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCEEEEHHCCEEEECCCCCCCCCCH
KNLWKPSALQYNFGPSFAVPLFDGGRLKATLHLREAQQQEAAIAYHKTVLGAWHEVVNTL
HHCCCCCCEEECCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYQKEQQRRARLNAQVDHARQVLSLSRTRYNTGVTDFITVLDAERTLLGAQQQYAQSTT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NVSTDLVALYKALGGGWEMVFPDKDAPTLATPEMTASVAPAPAAQ
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]