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The map label for this gene is cfa [H]

Identifier: 182678982

GI number: 182678982

Start: 2303940

End: 2305247

Strand: Reverse

Name: cfa [H]

Synonym: Bind_2017

Alternate gene names: 182678982

Gene position: 2305247-2303940 (Counterclockwise)

Preceding gene: 182678984

Following gene: 182678979

Centisome position: 55.28

GC content: 45.26

Gene sequence:

>1308_bases
ATGATTAAAAATTTCACGACCTTTGTTTCAGAAAATATTAAAACGGGTGACCTTGTCATCATCGAAGCCAATGGATGTCA
ACATCATTTTGGCGATGGGACAGGCAAACGTGTCACCATCCGTTTTACTGATAATAATATTCTCTTGGCGATCCTTCTGA
AACCAGAACTTGCGGCGGGCGAGGCGTTTATGGATGGACGTCTGCTTATGGTAGAGGGGGATATTTATGATTTTCTCGCC
TTGATATTCAGAAATACTTATACATTAAAAACTTCTAGACCAATAAAGCTTATTCGTCAGTTAATTAATTTCACCAAACG
ATTCAACGCGAACAATAAGCTCGGTAACGCGCAAAAGAACATCGCCTATCATTATGATCTTGATCAGTCTTTCTATCGCC
TATTTTTGGATGAGGATTGTCAATATTCCTGTGCTTATTTTGAGTATCCGGGGGAAACATTGGATGCGGCACAATCGGCA
AAAAAGAGACATATCGCCGCTAAACTGTTACTGAAGTCAAACCAGCATGTTCTCGACATTGGATCCGGGTGGGGTGGGCT
TGGCCTTTATCTGGCTCGTCTGTCAGGGGTCGAGGTTACAGGAGTGACGCTTTCCAAGGAACAATATATCAGTTCGAATA
AAGAAGCCGAACGGCTGAACCTTGCTCACCACGTACGATTTTTCTTAAAAGACTACCGCCTTCTGGATGAAACATTCGAT
CGCATCGTCTCCGTTGGCATGTTGGAGCACGTCGGAATTGGATCCTATGAAGAATATTTTGCTAAAGTGAAATCCCTGCT
GAAGCCCGACGGCGTGATGCTTTTGCATGCGATTGGCCAATTTGATAGTCCCACTTACACCAATCCATGGATTCAAAAAT
ATATTTTCCCGGGTGGCTATATTCCTGCCCTTTCCGAAGTTCTTCCCGCTATCGAACGACATGGCCTTGTCGTTTGTGAC
ATTGAGATCCTGCGATTACACTATGCGGAGACACTCAGGGCGTGGCGTGAGCGTTTTCTAGCGCGTCGTGAGGAAGCAGT
CGCTCTTTATGGGGAACGGTTTGCGCGGATGTGGGAGTTTTATCTTGCTGCATCCGAGACAGCGTTTCGTTACCAGGGTT
TGATGGTGTTCCAGATCCAGCTTGCGCGTGATCAAACGGTCGTGCCCCTAACGCGCAATTATATTGCCAAAAACGAGGAG
GCTCTGAAGACGCTGGAGAATGCCAAGCTTTTCTCTGTCCTCACTCCAGAATATTCGTCCGCGAAAAGCTCAGATGTGGA
TATCAATTCGGATATTGATATATTTTGA

Upstream 100 bases:

>100_bases
GTTGTTCGAAAGAGATTGAACTTCCGTTGCCTCTTACGCGTTGTCACTCCAAATTTACTGTCTGAAAATGTATTTCAGAC
AACATCTTTCAGGTTCTGAA

Downstream 100 bases:

>100_bases
TATCAAATATTTGATCTTGAGATCCGAATGTGTTTGCGACGAAGCCCCTATAAAACTTTACCGGGATTGAGGAGGTTTTG
GGGATCAAGCGCTGTTTTCA

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIKNFTTFVSENIKTGDLVIIEANGCQHHFGDGTGKRVTIRFTDNNILLAILLKPELAAGEAFMDGRLLMVEGDIYDFLA
LIFRNTYTLKTSRPIKLIRQLINFTKRFNANNKLGNAQKNIAYHYDLDQSFYRLFLDEDCQYSCAYFEYPGETLDAAQSA
KKRHIAAKLLLKSNQHVLDIGSGWGGLGLYLARLSGVEVTGVTLSKEQYISSNKEAERLNLAHHVRFFLKDYRLLDETFD
RIVSVGMLEHVGIGSYEEYFAKVKSLLKPDGVMLLHAIGQFDSPTYTNPWIQKYIFPGGYIPALSEVLPAIERHGLVVCD
IEILRLHYAETLRAWRERFLARREEAVALYGERFARMWEFYLAASETAFRYQGLMVFQIQLARDQTVVPLTRNYIAKNEE
ALKTLENAKLFSVLTPEYSSAKSSDVDINSDIDIF

Sequences:

>Translated_435_residues
MIKNFTTFVSENIKTGDLVIIEANGCQHHFGDGTGKRVTIRFTDNNILLAILLKPELAAGEAFMDGRLLMVEGDIYDFLA
LIFRNTYTLKTSRPIKLIRQLINFTKRFNANNKLGNAQKNIAYHYDLDQSFYRLFLDEDCQYSCAYFEYPGETLDAAQSA
KKRHIAAKLLLKSNQHVLDIGSGWGGLGLYLARLSGVEVTGVTLSKEQYISSNKEAERLNLAHHVRFFLKDYRLLDETFD
RIVSVGMLEHVGIGSYEEYFAKVKSLLKPDGVMLLHAIGQFDSPTYTNPWIQKYIFPGGYIPALSEVLPAIERHGLVVCD
IEILRLHYAETLRAWRERFLARREEAVALYGERFARMWEFYLAASETAFRYQGLMVFQIQLARDQTVVPLTRNYIAKNEE
ALKTLENAKLFSVLTPEYSSAKSSDVDINSDIDIF
>Mature_435_residues
MIKNFTTFVSENIKTGDLVIIEANGCQHHFGDGTGKRVTIRFTDNNILLAILLKPELAAGEAFMDGRLLMVEGDIYDFLA
LIFRNTYTLKTSRPIKLIRQLINFTKRFNANNKLGNAQKNIAYHYDLDQSFYRLFLDEDCQYSCAYFEYPGETLDAAQSA
KKRHIAAKLLLKSNQHVLDIGSGWGGLGLYLARLSGVEVTGVTLSKEQYISSNKEAERLNLAHHVRFFLKDYRLLDETFD
RIVSVGMLEHVGIGSYEEYFAKVKSLLKPDGVMLLHAIGQFDSPTYTNPWIQKYIFPGGYIPALSEVLPAIERHGLVVCD
IEILRLHYAETLRAWRERFLARREEAVALYGERFARMWEFYLAASETAFRYQGLMVFQIQLARDQTVVPLTRNYIAKNEE
ALKTLENAKLFSVLTPEYSSAKSSDVDINSDIDIF

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=346, Percent_Identity=39.8843930635838, Blast_Score=216, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI133904226, Length=371, Percent_Identity=27.2237196765499, Blast_Score=150, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 49673; Mature: 49673

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNFTTFVSENIKTGDLVIIEANGCQHHFGDGTGKRVTIRFTDNNILLAILLKPELAAG
CCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
EAFMDGRLLMVEGDIYDFLALIFRNTYTLKTSRPIKLIRQLINFTKRFNANNKLGNAQKN
CEEECCEEEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
IAYHYDLDQSFYRLFLDEDCQYSCAYFEYPGETLDAAQSAKKRHIAAKLLLKSNQHVLDI
EEEEECCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GSGWGGLGLYLARLSGVEVTGVTLSKEQYISSNKEAERLNLAHHVRFFLKDYRLLDETFD
CCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIVSVGMLEHVGIGSYEEYFAKVKSLLKPDGVMLLHAIGQFDSPTYTNPWIQKYIFPGGY
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCC
IPALSEVLPAIERHGLVVCDIEILRLHYAETLRAWRERFLARREEAVALYGERFARMWEF
HHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLAASETAFRYQGLMVFQIQLARDQTVVPLTRNYIAKNEEALKTLENAKLFSVLTPEYSS
HHHHCCHHHHHCCEEEEEEEECCCCEEECHHHHHHHCCHHHHHHHHCCEEEEEECCCCCC
AKSSDVDINSDIDIF
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKNFTTFVSENIKTGDLVIIEANGCQHHFGDGTGKRVTIRFTDNNILLAILLKPELAAG
CCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
EAFMDGRLLMVEGDIYDFLALIFRNTYTLKTSRPIKLIRQLINFTKRFNANNKLGNAQKN
CEEECCEEEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
IAYHYDLDQSFYRLFLDEDCQYSCAYFEYPGETLDAAQSAKKRHIAAKLLLKSNQHVLDI
EEEEECCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GSGWGGLGLYLARLSGVEVTGVTLSKEQYISSNKEAERLNLAHHVRFFLKDYRLLDETFD
CCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIVSVGMLEHVGIGSYEEYFAKVKSLLKPDGVMLLHAIGQFDSPTYTNPWIQKYIFPGGY
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCC
IPALSEVLPAIERHGLVVCDIEILRLHYAETLRAWRERFLARREEAVALYGERFARMWEF
HHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLAASETAFRYQGLMVFQIQLARDQTVVPLTRNYIAKNEEALKTLENAKLFSVLTPEYSS
HHHHCCHHHHHCCEEEEEEEECCCCEEECHHHHHHHCCHHHHHHHHCCEEEEEECCCCCC
AKSSDVDINSDIDIF
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]