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The map label for this gene is mgtC [H]

Identifier: 182678962

GI number: 182678962

Start: 2283058

End: 2283780

Strand: Direct

Name: mgtC [H]

Synonym: Bind_1996

Alternate gene names: 182678962

Gene position: 2283058-2283780 (Clockwise)

Preceding gene: 182678960

Following gene: 182678963

Centisome position: 54.75

GC content: 61.69

Gene sequence:

>723_bases
ATGCGTTTCATTCAAACCTTTGAGCTCGCACCCTTTCTGGATTCCTTCGTCAGCTTGTTTTCGGCTTTTGTGCTCGGCAC
GGCGATCGGCGCTGAGCGGCAATATCGCCAGCGTGTGCCGGGCTTGCGCACCAATGTTCTCGTCGCTGTCGGCGCAGCCG
CCTTTGTCGATCTCGCGGCGCGGATCGGCGGCACGGAGGGAGCGGTCCGCGTCATCGCTTATGTAGTCTCCGGCGTCGGT
TTCCTCGGCGCTGGCACGATCATGAAGGAGGGCGCCAATGTCCGCGGGCTCAATACGGCGGCGACGCTCTGGGCCTCGGC
CGCGGTCGGAGCCTGCGCCGGCGCCGACATGGTCGCCGAAGCCGTGATGGTGACGATATTCATTCTCATGGGCAATACGC
TGCTGCGGCCGGTGGTCAATCTCATCAACAGCCGGCCGCTCGACACGATTGCATCAGAAGGCGAATTCACCGTTCGCGTC
ACGGTGAACGACGAAGCGGTGCCCACTGTCCGCAATCAGCTCACACGTCAATTATCCACCGCCAATCTGCCGATCAGCGA
GATCGAGACCGAGGAAGTCTCGGATACGGTAACGGATCTGGTGGCCACGCTCGTTGCCACGTCGATCGATGCCAAGGCGC
TCGACGCGGCACTCGCCAATCTCCGCACACAACCAGACGTGCGCCATGCGAGCTGGGAAATGAATACAGCCGGGTCGGAA
TAA

Upstream 100 bases:

>100_bases
ACCTCCTCGTCACCCTTGTTCAATATTCTCCTGTTATGAAATGGGATTCCTCATCCGTCCCATGCCATCCCTCTCCCCGA
GGTTGAAACAGGCCGATTTC

Downstream 100 bases:

>100_bases
AGGCGCGAAAGACGCAACAAAAAAAGCGACGGCTGATCAAAGTCGAGCGATGCACGCTTTGTTGTTTCGCCAAAACTCTT
GCATTGGCTCGATGATGGAA

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRFIQTFELAPFLDSFVSLFSAFVLGTAIGAERQYRQRVPGLRTNVLVAVGAAAFVDLAARIGGTEGAVRVIAYVVSGVG
FLGAGTIMKEGANVRGLNTAATLWASAAVGACAGADMVAEAVMVTIFILMGNTLLRPVVNLINSRPLDTIASEGEFTVRV
TVNDEAVPTVRNQLTRQLSTANLPISEIETEEVSDTVTDLVATLVATSIDAKALDAALANLRTQPDVRHASWEMNTAGSE

Sequences:

>Translated_240_residues
MRFIQTFELAPFLDSFVSLFSAFVLGTAIGAERQYRQRVPGLRTNVLVAVGAAAFVDLAARIGGTEGAVRVIAYVVSGVG
FLGAGTIMKEGANVRGLNTAATLWASAAVGACAGADMVAEAVMVTIFILMGNTLLRPVVNLINSRPLDTIASEGEFTVRV
TVNDEAVPTVRNQLTRQLSTANLPISEIETEEVSDTVTDLVATLVATSIDAKALDAALANLRTQPDVRHASWEMNTAGSE
>Mature_240_residues
MRFIQTFELAPFLDSFVSLFSAFVLGTAIGAERQYRQRVPGLRTNVLVAVGAAAFVDLAARIGGTEGAVRVIAYVVSGVG
FLGAGTIMKEGANVRGLNTAATLWASAAVGACAGADMVAEAVMVTIFILMGNTLLRPVVNLINSRPLDTIASEGEFTVRV
TVNDEAVPTVRNQLTRQLSTANLPISEIETEEVSDTVTDLVATLVATSIDAKALDAALANLRTQPDVRHASWEMNTAGSE

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=193, Percent_Identity=31.0880829015544, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25255; Mature: 25255

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIQTFELAPFLDSFVSLFSAFVLGTAIGAERQYRQRVPGLRTNVLVAVGAAAFVDLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RIGGTEGAVRVIAYVVSGVGFLGAGTIMKEGANVRGLNTAATLWASAAVGACAGADMVAE
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
AVMVTIFILMGNTLLRPVVNLINSRPLDTIASEGEFTVRVTVNDEAVPTVRNQLTRQLST
HHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
ANLPISEIETEEVSDTVTDLVATLVATSIDAKALDAALANLRTQPDVRHASWEMNTAGSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MRFIQTFELAPFLDSFVSLFSAFVLGTAIGAERQYRQRVPGLRTNVLVAVGAAAFVDLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RIGGTEGAVRVIAYVVSGVGFLGAGTIMKEGANVRGLNTAATLWASAAVGACAGADMVAE
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
AVMVTIFILMGNTLLRPVVNLINSRPLDTIASEGEFTVRVTVNDEAVPTVRNQLTRQLST
HHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
ANLPISEIETEEVSDTVTDLVATLVATSIDAKALDAALANLRTQPDVRHASWEMNTAGSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA