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The map label for this gene is bigR [H]

Identifier: 182678908

GI number: 182678908

Start: 2211277

End: 2211666

Strand: Direct

Name: bigR [H]

Synonym: Bind_1942

Alternate gene names: 182678908

Gene position: 2211277-2211666 (Clockwise)

Preceding gene: 182678907

Following gene: 182678909

Centisome position: 53.03

GC content: 60.26

Gene sequence:

>390_bases
ATGGACCTTTCCTCTTTGTCACGATCTCAGGCCGAGGTGGCGAGCGAGCTTTTCAAAAGTCTCTCCAACCCCAATCGCCT
GCAGATCGTCGCAGCACTGGCGCTCGGCGAGCATCCCGTCGGCGATCTCGAAACCATGCTCGGCATCAAACAGCCGACCT
TGTCGCAGCAATTGGCTGAACTCCGGGACGCAGGCTTCGTCGAGTCCCGGCGCGAAGCAAAACAGGTTTTCTACCGCCTC
GGCGACAAGCGCCTTCTCGCCTTGCTGCATGCCCTGCCGGGCATTTTGCAGGGCGAGATCCCGCTCAAACATGAGGCTTT
CATGAAGGAACAAAGGCTTACTGGCACCGCCGCCGCCATGTTCGCGCGGGTCGAGCCACCCCCTTCGTAA

Upstream 100 bases:

>100_bases
TGCGGGTCAATTGCCGCCACCTGAAGACAATCAAAGGCATTATTTGAAAATTCCGATCGGAGCCTTCCCCGGCGCGGTTT
GGTAAATCGGGAGGAATGTT

Downstream 100 bases:

>100_bases
AAAAACTCGATCCCCTTCACCAACTTTCCTTTGAGCCCTGAGAGAGCATGATCATGCTAAGGGACACGCTTGCCCTTTTG
TCCGGGGCCCTGTCTGGATT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MDLSSLSRSQAEVASELFKSLSNPNRLQIVAALALGEHPVGDLETMLGIKQPTLSQQLAELRDAGFVESRREAKQVFYRL
GDKRLLALLHALPGILQGEIPLKHEAFMKEQRLTGTAAAMFARVEPPPS

Sequences:

>Translated_129_residues
MDLSSLSRSQAEVASELFKSLSNPNRLQIVAALALGEHPVGDLETMLGIKQPTLSQQLAELRDAGFVESRREAKQVFYRL
GDKRLLALLHALPGILQGEIPLKHEAFMKEQRLTGTAAAMFARVEPPPS
>Mature_129_residues
MDLSSLSRSQAEVASELFKSLSNPNRLQIVAALALGEHPVGDLETMLGIKQPTLSQQLAELRDAGFVESRREAKQVFYRL
GDKRLLALLHALPGILQGEIPLKHEAFMKEQRLTGTAAAMFARVEPPPS

Specific function: Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14161; Mature: 14161

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSSLSRSQAEVASELFKSLSNPNRLQIVAALALGEHPVGDLETMLGIKQPTLSQQLAE
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHH
LRDAGFVESRREAKQVFYRLGDKRLLALLHALPGILQGEIPLKHEAFMKEQRLTGTAAAM
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FARVEPPPS
HHHCCCCCC
>Mature Secondary Structure
MDLSSLSRSQAEVASELFKSLSNPNRLQIVAALALGEHPVGDLETMLGIKQPTLSQQLAE
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHH
LRDAGFVESRREAKQVFYRLGDKRLLALLHALPGILQGEIPLKHEAFMKEQRLTGTAAAM
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FARVEPPPS
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]