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The map label for this gene is blh [H]

Identifier: 182678907

GI number: 182678907

Start: 2210347

End: 2211261

Strand: Direct

Name: blh [H]

Synonym: Bind_1941

Alternate gene names: 182678907

Gene position: 2210347-2211261 (Clockwise)

Preceding gene: 182678906

Following gene: 182678908

Centisome position: 53.0

GC content: 54.43

Gene sequence:

>915_bases
ATGCACACTCCCCTCGCCTTACACGACACACTTCCTGCTTCAGCCGATAAACCACTCGTCGAAGCCTTTTATGATTCTGC
GACCGGCAGCATTCAATATGTCGTTGTCTGTCCCGTCACGCGCGCCTGCGCCATTATCGATCCGGTCTTGGACTTCGACG
AAAAATCCGGTTCGATCGCCACCAGAAACGCTGATGCGATCCTCGATTACATCCGCAAACAGGGGCTACAGGTCGCCTGG
ATTCTCGATACACATCCGCATGCTGATCATTTCTCGGCCTCCTTCTATCTCAAGACACAGACCGGCGCCCCCATGGGTAT
TGGCGATCATGTCACGGCTGTTCAGTCTTTGTGGAGAGACATTTACAATTGGCCGGACTTTCCCGCTGACGGTTCGCAAT
GGGACAGATTGTTCAAGTCGGGCGACTCGTTTCAGATCGGCAATCTCGAGGTAAATGTCATTTTATCGCCAGGTCATACA
CCGGCCTCGATCACTTATCTGATCGGCAATGCCGTCTTTGTGCATGATACCCTGTTCATGCCGGATTCCGGCACGGCCCG
CGCCGATTTTCCCGGCGGCAACGCCGCCTTGCTCTGGCAATCGATCCAAACGCTTCTCACACTGCCAGACGAGACCCGTG
TCTTTACAGGACATGATTATCCACCGGTGGGACGCCAGGCGAGCTGGGAAAGCACGATTGGCGAGCAGAAACGCCACAAT
ATTCACGTGACAGGGAAAACTGAAAGCGATTTCATTGCCCTGCGCCATAAACGTGACAGCGGCCTGCCCCTGCCACACCT
GCTCCTGCCTGCGCTTCAGGTGAATATCAATGCGGGTCAATTGCCGCCACCTGAAGACAATCAAAGGCATTATTTGAAAA
TTCCGATCGGAGCCTTCCCCGGCGCGGTTTGGTAA

Upstream 100 bases:

>100_bases
CGAAGCGATTGGCGCTGACAATGCCGCGCTCGATCATGAACGGGACCAAGAACTCGGTACCGATTGGTATTATCGTCTTC
GCAAGCTGTGAGAGGCCATC

Downstream 100 bases:

>100_bases
ATCGGGAGGAATGTTATGGACCTTTCCTCTTTGTCACGATCTCAGGCCGAGGTGGCGAGCGAGCTTTTCAAAAGTCTCTC
CAACCCCAATCGCCTGCAGA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MHTPLALHDTLPASADKPLVEAFYDSATGSIQYVVVCPVTRACAIIDPVLDFDEKSGSIATRNADAILDYIRKQGLQVAW
ILDTHPHADHFSASFYLKTQTGAPMGIGDHVTAVQSLWRDIYNWPDFPADGSQWDRLFKSGDSFQIGNLEVNVILSPGHT
PASITYLIGNAVFVHDTLFMPDSGTARADFPGGNAALLWQSIQTLLTLPDETRVFTGHDYPPVGRQASWESTIGEQKRHN
IHVTGKTESDFIALRHKRDSGLPLPHLLLPALQVNINAGQLPPPEDNQRHYLKIPIGAFPGAVW

Sequences:

>Translated_304_residues
MHTPLALHDTLPASADKPLVEAFYDSATGSIQYVVVCPVTRACAIIDPVLDFDEKSGSIATRNADAILDYIRKQGLQVAW
ILDTHPHADHFSASFYLKTQTGAPMGIGDHVTAVQSLWRDIYNWPDFPADGSQWDRLFKSGDSFQIGNLEVNVILSPGHT
PASITYLIGNAVFVHDTLFMPDSGTARADFPGGNAALLWQSIQTLLTLPDETRVFTGHDYPPVGRQASWESTIGEQKRHN
IHVTGKTESDFIALRHKRDSGLPLPHLLLPALQVNINAGQLPPPEDNQRHYLKIPIGAFPGAVW
>Mature_304_residues
MHTPLALHDTLPASADKPLVEAFYDSATGSIQYVVVCPVTRACAIIDPVLDFDEKSGSIATRNADAILDYIRKQGLQVAW
ILDTHPHADHFSASFYLKTQTGAPMGIGDHVTAVQSLWRDIYNWPDFPADGSQWDRLFKSGDSFQIGNLEVNVILSPGHT
PASITYLIGNAVFVHDTLFMPDSGTARADFPGGNAALLWQSIQTLLTLPDETRVFTGHDYPPVGRQASWESTIGEQKRHN
IHVTGKTESDFIALRHKRDSGLPLPHLLLPALQVNINAGQLPPPEDNQRHYLKIPIGAFPGAVW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=268, Percent_Identity=25.7462686567164, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787158, Length=218, Percent_Identity=27.5229357798165, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=268, Percent_Identity=26.4925373134328, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330176, Length=285, Percent_Identity=26.6666666666667, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33400; Mature: 33400

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPLALHDTLPASADKPLVEAFYDSATGSIQYVVVCPVTRACAIIDPVLDFDEKSGSIA
CCCCEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEE
TRNADAILDYIRKQGLQVAWILDTHPHADHFSASFYLKTQTGAPMGIGDHVTAVQSLWRD
ECCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IYNWPDFPADGSQWDRLFKSGDSFQIGNLEVNVILSPGHTPASITYLIGNAVFVHDTLFM
HHCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCCCCCCEEEEEECCEEEEEEEEEC
PDSGTARADFPGGNAALLWQSIQTLLTLPDETRVFTGHDYPPVGRQASWESTIGEQKRHN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCHHHCCE
IHVTGKTESDFIALRHKRDSGLPLPHLLLPALQVNINAGQLPPPEDNQRHYLKIPIGAFP
EEEECCCCCCEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCEEEEEECCCCC
GAVW
CCCC
>Mature Secondary Structure
MHTPLALHDTLPASADKPLVEAFYDSATGSIQYVVVCPVTRACAIIDPVLDFDEKSGSIA
CCCCEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEE
TRNADAILDYIRKQGLQVAWILDTHPHADHFSASFYLKTQTGAPMGIGDHVTAVQSLWRD
ECCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IYNWPDFPADGSQWDRLFKSGDSFQIGNLEVNVILSPGHTPASITYLIGNAVFVHDTLFM
HHCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCCCCCCEEEEEECCEEEEEEEEEC
PDSGTARADFPGGNAALLWQSIQTLLTLPDETRVFTGHDYPPVGRQASWESTIGEQKRHN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCHHHCCE
IHVTGKTESDFIALRHKRDSGLPLPHLLLPALQVNINAGQLPPPEDNQRHYLKIPIGAFP
EEEECCCCCCEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCEEEEEECCCCC
GAVW
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]