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The map label for this gene is ahpC [C]

Identifier: 182678906

GI number: 182678906

Start: 2209639

End: 2210337

Strand: Direct

Name: ahpC [C]

Synonym: Bind_1940

Alternate gene names: 182678906

Gene position: 2209639-2210337 (Clockwise)

Preceding gene: 182678904

Following gene: 182678907

Centisome position: 52.99

GC content: 59.23

Gene sequence:

>699_bases
TTGAGCGAGACGATCCGAGAGAAATCATTAGAGAAACCCCAAGACCGCCGCACCGCGCAGCCGCTGCTTCTCGGCAGCCA
GGCCCCGCTCTTCGTCGCGCGCACCACAATGGGCGAACGGGCCCTGGCTCATTATCGTGGCCGCTGGCTCGTCCTGTTCT
CGCATCCCGCCGATTTCACGCCTGTCTGCACGAGCGAATTCATCGCATTTGCCAAAGCTTATCAACGCTTCCAAGCCTTG
GACTGTGATCTTCTTGGACTTTCCGTCGACAGCCTGTTCTCCCATATCGCCTGGGTCCGTTCGATCAAGCAGCGCTTCGG
CGTTGAAATCCCATTCCCCGTGATCGAGGACCCATCCATGGCGATCGCCAGCGCCTATGGAATGATCCATGCCGATGCTG
CCGACAGTTCCACGGTCAGGGCCTCGTTCATCATCGATCCCGATGGGGTGATCCGTCTCATCCTTTGGTACCCCATGAGC
ATTGGCCGCTCTGTCGAGGAGATCCTGCGCGTCGTCGAGGCCTTGCAGGTTTCAGATAGCGCCGCTGTTTCCACGCCCGA
GGGATGGCACCCGGGTGATCCGGTCATCGAGACCCCACCGCTCGATGTCGAAGCGATTGGCGCTGACAATGCCGCGCTCG
ATCATGAACGGGACCAAGAACTCGGTACCGATTGGTATTATCGTCTTCGCAAGCTGTGA

Upstream 100 bases:

>100_bases
ATAGAATATTTAATTGTTAATTGAAAGCGGCAAGATCCTTTAGGCCTGCCCTTAAAAATGAGTAGGCACAGGCGTCGCCC
ATCGAGAGAAAGAGTTTTCC

Downstream 100 bases:

>100_bases
GAGGCCATCATGCACACTCCCCTCGCCTTACACGACACACTTCCTGCTTCAGCCGATAAACCACTCGTCGAAGCCTTTTA
TGATTCTGCGACCGGCAGCA

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSETIREKSLEKPQDRRTAQPLLLGSQAPLFVARTTMGERALAHYRGRWLVLFSHPADFTPVCTSEFIAFAKAYQRFQAL
DCDLLGLSVDSLFSHIAWVRSIKQRFGVEIPFPVIEDPSMAIASAYGMIHADAADSSTVRASFIIDPDGVIRLILWYPMS
IGRSVEEILRVVEALQVSDSAAVSTPEGWHPGDPVIETPPLDVEAIGADNAALDHERDQELGTDWYYRLRKL

Sequences:

>Translated_232_residues
MSETIREKSLEKPQDRRTAQPLLLGSQAPLFVARTTMGERALAHYRGRWLVLFSHPADFTPVCTSEFIAFAKAYQRFQAL
DCDLLGLSVDSLFSHIAWVRSIKQRFGVEIPFPVIEDPSMAIASAYGMIHADAADSSTVRASFIIDPDGVIRLILWYPMS
IGRSVEEILRVVEALQVSDSAAVSTPEGWHPGDPVIETPPLDVEAIGADNAALDHERDQELGTDWYYRLRKL
>Mature_231_residues
SETIREKSLEKPQDRRTAQPLLLGSQAPLFVARTTMGERALAHYRGRWLVLFSHPADFTPVCTSEFIAFAKAYQRFQALD
CDLLGLSVDSLFSHIAWVRSIKQRFGVEIPFPVIEDPSMAIASAYGMIHADAADSSTVRASFIIDPDGVIRLILWYPMSI
GRSVEEILRVVEALQVSDSAAVSTPEGWHPGDPVIETPPLDVEAIGADNAALDHERDQELGTDWYYRLRKL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=39.4444444444444, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=39.4444444444444, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=39.4444444444444, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4758638, Length=187, Percent_Identity=39.572192513369, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32189392, Length=184, Percent_Identity=37.5, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI5453549, Length=159, Percent_Identity=38.3647798742138, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI32483377, Length=180, Percent_Identity=35, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=34.0782122905028, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI33188454, Length=86, Percent_Identity=41.8604651162791, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786822, Length=159, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25153706, Length=194, Percent_Identity=36.0824742268041, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI193204376, Length=186, Percent_Identity=36.0215053763441, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565831, Length=180, Percent_Identity=36.6666666666667, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17554494, Length=154, Percent_Identity=37.012987012987, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319407, Length=195, Percent_Identity=44.1025641025641, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323613, Length=177, Percent_Identity=35.0282485875706, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320661, Length=177, Percent_Identity=32.7683615819209, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17975518, Length=188, Percent_Identity=42.5531914893617, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24652434, Length=188, Percent_Identity=42.5531914893617, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24652436, Length=188, Percent_Identity=42.5531914893617, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17157991, Length=182, Percent_Identity=35.7142857142857, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641739, Length=182, Percent_Identity=35.7142857142857, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24581278, Length=196, Percent_Identity=34.1836734693878, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=35.0282485875706, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=31.9587628865979, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=31.9587628865979, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357347, Length=153, Percent_Identity=40.5228758169935, Blast_Score=118, Evalue=3e-27,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25884; Mature: 25753

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETIREKSLEKPQDRRTAQPLLLGSQAPLFVARTTMGERALAHYRGRWLVLFSHPADFT
CCCHHHHHHCCCCHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCC
PVCTSEFIAFAKAYQRFQALDCDLLGLSVDSLFSHIAWVRSIKQRFGVEIPFPVIEDPSM
CHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AIASAYGMIHADAADSSTVRASFIIDPDGVIRLILWYPMSIGRSVEEILRVVEALQVSDS
HHHHHHCEEEECCCCCCCEEEEEEECCCHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCC
AAVSTPEGWHPGDPVIETPPLDVEAIGADNAALDHERDQELGTDWYYRLRKL
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHCHHHHHHHHCC
>Mature Secondary Structure 
SETIREKSLEKPQDRRTAQPLLLGSQAPLFVARTTMGERALAHYRGRWLVLFSHPADFT
CCHHHHHHCCCCHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCC
PVCTSEFIAFAKAYQRFQALDCDLLGLSVDSLFSHIAWVRSIKQRFGVEIPFPVIEDPSM
CHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AIASAYGMIHADAADSSTVRASFIIDPDGVIRLILWYPMSIGRSVEEILRVVEALQVSDS
HHHHHHCEEEECCCCCCCEEEEEEECCCHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCC
AAVSTPEGWHPGDPVIETPPLDVEAIGADNAALDHERDQELGTDWYYRLRKL
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]