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The map label for this gene is aroB [H]

Identifier: 182678894

GI number: 182678894

Start: 2196721

End: 2197857

Strand: Reverse

Name: aroB [H]

Synonym: Bind_1927

Alternate gene names: 182678894

Gene position: 2197857-2196721 (Counterclockwise)

Preceding gene: 182678895

Following gene: 182678893

Centisome position: 52.7

GC content: 62.01

Gene sequence:

>1137_bases
ATGCAGACGATTCAAGGTGCCAATGGTAAGAGCCGAACACGAAGCGGCAATGGATTCATGAATCCACCCTTGCCGCTTGG
CTCCCTTGCTTCATTGCCGCCGCGTCCGGCGCGGAACCCCATTTATGCCGCACTCGATCTCGGCACCAATAATTGCCGCT
TGTTGATCGCGAAGCCGACCTTGAATGCCGCTTGTCAGGGCGGTTTCCGCGTCGTCGATTCCTTCTCCCGCATCGTCCGC
CTTGGCGAGGGGCTCTCGCGCACGGGTCAATTGGGACAGGCGGCGATTGATCGGACCTTGGAAGCGCTGGAAATCTGCCG
CGACAAGATGGTGGCTCGGGGCGTGACCCGCGCGCGCCTCATTGCGACGGAAGCCTGCCGCTCGGCTGAAAATGGCGCCG
CCTTCCTCGAACAGGCGCGGGCTTTGACTGGTCTCGATCTAGAAGTCGTCGATCGTGAGACGGAAGCCCATCTTGCGGCC
GCAGGATCGGCCTCGCTCGCCGATGCCTCGGCTGAAGGTGTCCTGCTTTTCGATATAGGCGGTGGATCCTCCGAGGTCGT
CTGGCTCGGTCGCGAGCGCGAGAATGCATCGGAAGGCGCCAAGGCTCTCGATGAGAGCCTGCGCGAGCGGGTCCGGTTCT
GGACCTCACTCAAGCTCGGCGTGGTGACGCTGGCGGAAAAATTCGGCGGTCTCGACGTGTCCGATCGCACTTTCGAGGCG
ATGGTCGATTATGTCGGCGAGCAACTGGCCCATTTTGTGGAAAAGGTCGGCACGGAGCATCGCTGCCGCAATTTCCATCT
GCTCGGCACATCCGGCACGGTGACGACGATTGCCGGCGTCTATCTTGGCCTTTCCCGTTACGACCGGCGGCGCGTCGATG
GCCTGTGGATGACCAGTTACGAAGTCGATCATGCCATCTTGCGCCTGCGCGGCATGAGCTACGATGAACGCGCGGCCAAT
GGTTGTATCGGTCTCGGCCGCGCTGATCTGGTATTGGCCGGCTGCGCCATTCTCGAGGCGATCCGCCGGGCTTTTCCGGC
CGAGCGCGTGCGCATTGCCGACCGTGGTCTGCGCGAAGGCATTTTGATGCAAATGATTAACGCGGACCGGTTGCACGCCG
GGACGGAAGGGCGCTAA

Upstream 100 bases:

>100_bases
GATAGGCCGCGACAGAGCGCCGCTTCTTCGAAAGGTAGGGGTACGCCCGGTCGAGTGGCATATTGGGAACCAGGCGCCGA
ATCATGACGGCAAGGACGCG

Downstream 100 bases:

>100_bases
AGCCTCCTCCATGAACGATGTTTCTTCTTCTGGCCGCGAGGGCGGCCGCTCGCTGAAGACGCGGGTCAAGACTGCACGCA
AGCGGTCCTTGTCCTCGACG

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQTIQGANGKSRTRSGNGFMNPPLPLGSLASLPPRPARNPIYAALDLGTNNCRLLIAKPTLNAACQGGFRVVDSFSRIVR
LGEGLSRTGQLGQAAIDRTLEALEICRDKMVARGVTRARLIATEACRSAENGAAFLEQARALTGLDLEVVDRETEAHLAA
AGSASLADASAEGVLLFDIGGGSSEVVWLGRERENASEGAKALDESLRERVRFWTSLKLGVVTLAEKFGGLDVSDRTFEA
MVDYVGEQLAHFVEKVGTEHRCRNFHLLGTSGTVTTIAGVYLGLSRYDRRRVDGLWMTSYEVDHAILRLRGMSYDERAAN
GCIGLGRADLVLAGCAILEAIRRAFPAERVRIADRGLREGILMQMINADRLHAGTEGR

Sequences:

>Translated_378_residues
MQTIQGANGKSRTRSGNGFMNPPLPLGSLASLPPRPARNPIYAALDLGTNNCRLLIAKPTLNAACQGGFRVVDSFSRIVR
LGEGLSRTGQLGQAAIDRTLEALEICRDKMVARGVTRARLIATEACRSAENGAAFLEQARALTGLDLEVVDRETEAHLAA
AGSASLADASAEGVLLFDIGGGSSEVVWLGRERENASEGAKALDESLRERVRFWTSLKLGVVTLAEKFGGLDVSDRTFEA
MVDYVGEQLAHFVEKVGTEHRCRNFHLLGTSGTVTTIAGVYLGLSRYDRRRVDGLWMTSYEVDHAILRLRGMSYDERAAN
GCIGLGRADLVLAGCAILEAIRRAFPAERVRIADRGLREGILMQMINADRLHAGTEGR
>Mature_378_residues
MQTIQGANGKSRTRSGNGFMNPPLPLGSLASLPPRPARNPIYAALDLGTNNCRLLIAKPTLNAACQGGFRVVDSFSRIVR
LGEGLSRTGQLGQAAIDRTLEALEICRDKMVARGVTRARLIATEACRSAENGAAFLEQARALTGLDLEVVDRETEAHLAA
AGSASLADASAEGVLLFDIGGGSSEVVWLGRERENASEGAKALDESLRERVRFWTSLKLGVVTLAEKFGGLDVSDRTFEA
MVDYVGEQLAHFVEKVGTEHRCRNFHLLGTSGTVTTIAGVYLGLSRYDRRRVDGLWMTSYEVDHAILRLRGMSYDERAAN
GCIGLGRADLVLAGCAILEAIRRAFPAERVRIADRGLREGILMQMINADRLHAGTEGR

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=329, Percent_Identity=26.7477203647416, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788848, Length=342, Percent_Identity=25.1461988304094, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40824; Mature: 40824

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIQGANGKSRTRSGNGFMNPPLPLGSLASLPPRPARNPIYAALDLGTNNCRLLIAKPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCC
LNAACQGGFRVVDSFSRIVRLGEGLSRTGQLGQAAIDRTLEALEICRDKMVARGVTRARL
CCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IATEACRSAENGAAFLEQARALTGLDLEVVDRETEAHLAAAGSASLADASAEGVLLFDIG
HHHHHHHCCCCHHHHHHHHHHHCCCCHHEECCCHHHHHHHCCCCHHCCCCCCCEEEEEEC
GGSSEVVWLGRERENASEGAKALDESLRERVRFWTSLKLGVVTLAEKFGGLDVSDRTFEA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVDYVGEQLAHFVEKVGTEHRCRNFHLLGTSGTVTTIAGVYLGLSRYDRRRVDGLWMTSY
HHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEHH
EVDHAILRLRGMSYDERAANGCIGLGRADLVLAGCAILEAIRRAFPAERVRIADRGLREG
HHHHHHHHHHCCCCHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ILMQMINADRLHAGTEGR
HHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MQTIQGANGKSRTRSGNGFMNPPLPLGSLASLPPRPARNPIYAALDLGTNNCRLLIAKPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCC
LNAACQGGFRVVDSFSRIVRLGEGLSRTGQLGQAAIDRTLEALEICRDKMVARGVTRARL
CCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IATEACRSAENGAAFLEQARALTGLDLEVVDRETEAHLAAAGSASLADASAEGVLLFDIG
HHHHHHHCCCCHHHHHHHHHHHCCCCHHEECCCHHHHHHHCCCCHHCCCCCCCEEEEEEC
GGSSEVVWLGRERENASEGAKALDESLRERVRFWTSLKLGVVTLAEKFGGLDVSDRTFEA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVDYVGEQLAHFVEKVGTEHRCRNFHLLGTSGTVTTIAGVYLGLSRYDRRRVDGLWMTSY
HHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEHH
EVDHAILRLRGMSYDERAANGCIGLGRADLVLAGCAILEAIRRAFPAERVRIADRGLREG
HHHHHHHHHHCCCCHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ILMQMINADRLHAGTEGR
HHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]