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The map label for this gene is mcpA [H]

Identifier: 182678769

GI number: 182678769

Start: 2037526

End: 2039373

Strand: Direct

Name: mcpA [H]

Synonym: Bind_1798

Alternate gene names: 182678769

Gene position: 2037526-2039373 (Clockwise)

Preceding gene: 182678765

Following gene: 182678775

Centisome position: 48.86

GC content: 56.98

Gene sequence:

>1848_bases
ATGAGGCTCTCCATCTCCTCTCTTTCAATCGGCCGTTCTATTTCCCTGATTGTCTTGCTGACGGCTGTGGTCGTCCTGAC
AAGCCTTGGTTTCGAGCTCTATCGAACACGTCTCAATCTGATCGAACAGAAGAGATCAGAGATCCGCCATGTTGTCGAAA
CCGCCGCCTCGATCGTCGAGGGTTTTGCTGCAAAAGCCAAGGCGGGGGAGATGACTGAGCGCGAGGCCCAGCGACAAGCC
CTCGCCGCGATCGATCCAGCCCGTTTCGATGGCAATAATTATTTCTTCATTTATGCTGATACGATCCGCATCGCTCATCC
AAACAAGGCCAGTATCGGCAAGGATTTCGCCAATGACGTCGATTCGCACGGCAAATATTATTTGAGGGACATGATCGCCA
CCGCCAAGGCCGGTGGTGGTTACGTCGACTATTATTTTAACAAGATCAATGACACCAATTCCTACCCCAAGACCTCCTAT
ATCTCGCCGATTGCGGACTGGAACTGGGCGATCGGAGCTGGCGCCTATATGGATGATATCGATCGCCTGTTCTGGCAATC
CTCCTTCGAGCTGCTGCTGATTCTCATCCCCCTTTTTTCGCTTCTCCTCGGTATCTTGTTCCTGATACGCAAGCAGATCA
CCGTCCTTCTGCAAAGGCTTGCGGCCAATACCAAGGCCTTGGCTGCGGGTGATTTGAATGTCGCCGTCGAGGCTCAGACC
CGTTCCGATGAAATTGGCGAACTCGCCCGGGCGCTGCAAATCTTCAAGGACAATTCCCTGACGCTTGAGAAAACCCGGCG
TGATAATCTGGCGCTCGAAGCCTCGGCCGCAGAGGAGCGTCAGCGCAATGAAGCCGCCCGCCAAAAGGCGGCGGCCTATC
AGACCGAAGTCGTGAGAAGCCTGTCGAGAGAGCTGGAGCGTATCGCCACCGGCGACATGACCGCCTTCATTGAAGAGAAT
TTTTCCTCCGATTACGCAAAATTACGCGATGATTTCAATATTTCCGTCCAGCATATGCGGCAAAGCATCGCTGCCATTCA
AAGCCATATGCGGGCGATCCGCTCTGGCACGAGTGAGATTTCAAGTGCCACCGATGATCTGTCGCGGCGCACCGAACAGC
AGGCAGCAAGCCTGGAAGAGACGGCCGCCGCTCTCGATGAAATCACCGCTACCGTGAAGAAAACCGCCGAGGGCGCGACC
CATGCCCGCGATGTCGTCTCCACCGCCAAGGCCGATGCCGACAAGAGCGGCGCCGTTGTCGCCGAAGCGATCAAAGCCAT
GGGCGGCATAGAACAATCCTCCGCCCAGATCGGCCAGATCATCGGCGTCATCGATGAAATCGCCTTTCAAACCAATCTCC
TTGCCCTCAATGCCGGTGTCGAGGCGGCCAGAGCTGGCGAAGCGGGGCGCGGTTTCGCCGTCGTCGCCTCGGAAGTCCGC
GCTTTGGCCCAGCGTTCGGCCGAGGCTGCCAAGGAAATCAAGACCCTGATCCAGGCTTCGAGCACACAGGTCAATCAGGG
CGTCGATCTGGTCGGGGAAACGGGTAAGGCGCTCGACCGCATCGTGGCCCAGGTCAGCGAGATCAACCGGATCGTCGCGG
AGATCGCTGCCAGCGCCCATGAGCAGGCGACCGGCCTGCATCAGGTCAACACCGCCATCAACCAGATGGATCAAATCACC
CAACAGAACGCCGCCATGGTGGAGGAAACCACCGCTGCGGCCCATGCTCTGATGCGGGAAAGCGAGGAGCTCGCACAACG
AATTGATCGGTTCGAAATCGGAGACGCAAAAGTCCCCTCCAATTCACGGGAGAGACAAGGTCAAAAGCGTCTTCTCAGCG
TGGCATGA

Upstream 100 bases:

>100_bases
GAAAAGAGTTCAGGCATTTCCTGGATAAACCAATAAGCGGCCCAGCCGCATGATTCCATTGATTATAAATGTCATTTTAA
AATTAAAATTGGATAAAATC

Downstream 100 bases:

>100_bases
CGATTTCACAACAAATACAGTTCGTCATTAGCGAGACCAGCTCTCTCCTATTCTTTTGCCGCCAAGGTCTGCAGGTGCGC
TTTATCGCAATGATTGTCCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRLSISSLSIGRSISLIVLLTAVVVLTSLGFELYRTRLNLIEQKRSEIRHVVETAASIVEGFAAKAKAGEMTEREAQRQA
LAAIDPARFDGNNYFFIYADTIRIAHPNKASIGKDFANDVDSHGKYYLRDMIATAKAGGGYVDYYFNKINDTNSYPKTSY
ISPIADWNWAIGAGAYMDDIDRLFWQSSFELLLILIPLFSLLLGILFLIRKQITVLLQRLAANTKALAAGDLNVAVEAQT
RSDEIGELARALQIFKDNSLTLEKTRRDNLALEASAAEERQRNEAARQKAAAYQTEVVRSLSRELERIATGDMTAFIEEN
FSSDYAKLRDDFNISVQHMRQSIAAIQSHMRAIRSGTSEISSATDDLSRRTEQQAASLEETAAALDEITATVKKTAEGAT
HARDVVSTAKADADKSGAVVAEAIKAMGGIEQSSAQIGQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVR
ALAQRSAEAAKEIKTLIQASSTQVNQGVDLVGETGKALDRIVAQVSEINRIVAEIAASAHEQATGLHQVNTAINQMDQIT
QQNAAMVEETTAAAHALMRESEELAQRIDRFEIGDAKVPSNSRERQGQKRLLSVA

Sequences:

>Translated_615_residues
MRLSISSLSIGRSISLIVLLTAVVVLTSLGFELYRTRLNLIEQKRSEIRHVVETAASIVEGFAAKAKAGEMTEREAQRQA
LAAIDPARFDGNNYFFIYADTIRIAHPNKASIGKDFANDVDSHGKYYLRDMIATAKAGGGYVDYYFNKINDTNSYPKTSY
ISPIADWNWAIGAGAYMDDIDRLFWQSSFELLLILIPLFSLLLGILFLIRKQITVLLQRLAANTKALAAGDLNVAVEAQT
RSDEIGELARALQIFKDNSLTLEKTRRDNLALEASAAEERQRNEAARQKAAAYQTEVVRSLSRELERIATGDMTAFIEEN
FSSDYAKLRDDFNISVQHMRQSIAAIQSHMRAIRSGTSEISSATDDLSRRTEQQAASLEETAAALDEITATVKKTAEGAT
HARDVVSTAKADADKSGAVVAEAIKAMGGIEQSSAQIGQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVR
ALAQRSAEAAKEIKTLIQASSTQVNQGVDLVGETGKALDRIVAQVSEINRIVAEIAASAHEQATGLHQVNTAINQMDQIT
QQNAAMVEETTAAAHALMRESEELAQRIDRFEIGDAKVPSNSRERQGQKRLLSVA
>Mature_615_residues
MRLSISSLSIGRSISLIVLLTAVVVLTSLGFELYRTRLNLIEQKRSEIRHVVETAASIVEGFAAKAKAGEMTEREAQRQA
LAAIDPARFDGNNYFFIYADTIRIAHPNKASIGKDFANDVDSHGKYYLRDMIATAKAGGGYVDYYFNKINDTNSYPKTSY
ISPIADWNWAIGAGAYMDDIDRLFWQSSFELLLILIPLFSLLLGILFLIRKQITVLLQRLAANTKALAAGDLNVAVEAQT
RSDEIGELARALQIFKDNSLTLEKTRRDNLALEASAAEERQRNEAARQKAAAYQTEVVRSLSRELERIATGDMTAFIEEN
FSSDYAKLRDDFNISVQHMRQSIAAIQSHMRAIRSGTSEISSATDDLSRRTEQQAASLEETAAALDEITATVKKTAEGAT
HARDVVSTAKADADKSGAVVAEAIKAMGGIEQSSAQIGQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVR
ALAQRSAEAAKEIKTLIQASSTQVNQGVDLVGETGKALDRIVAQVSEINRIVAEIAASAHEQATGLHQVNTAINQMDQIT
QQNAAMVEETTAAAHALMRESEELAQRIDRFEIGDAKVPSNSRERQGQKRLLSVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=310, Percent_Identity=44.1935483870968, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=48.2889733840304, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1788195, Length=293, Percent_Identity=47.098976109215, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI1788194, Length=262, Percent_Identity=46.9465648854962, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789453, Length=285, Percent_Identity=37.5438596491228, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66910; Mature: 66910

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSISSLSIGRSISLIVLLTAVVVLTSLGFELYRTRLNLIEQKRSEIRHVVETAASIVE
CCEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAAKAKAGEMTEREAQRQALAAIDPARFDGNNYFFIYADTIRIAHPNKASIGKDFANDV
HHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEEEEECCCCCHHCHHHHHHH
DSHGKYYLRDMIATAKAGGGYVDYYFNKINDTNSYPKTSYISPIADWNWAIGAGAYMDDI
HHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
DRLFWQSSFELLLILIPLFSLLLGILFLIRKQITVLLQRLAANTKALAAGDLNVAVEAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCEEEEEECC
RSDEIGELARALQIFKDNSLTLEKTRRDNLALEASAAEERQRNEAARQKAAAYQTEVVRS
CCHHHHHHHHHHHHHCCCCCEEHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRELERIATGDMTAFIEENFSSDYAKLRDDFNISVQHMRQSIAAIQSHMRAIRSGTSEI
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
SSATDDLSRRTEQQAASLEETAAALDEITATVKKTAEGATHARDVVSTAKADADKSGAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHH
AEAIKAMGGIEQSSAQIGQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHH
ALAQRSAEAAKEIKTLIQASSTQVNQGVDLVGETGKALDRIVAQVSEINRIVAEIAASAH
HHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQATGLHQVNTAINQMDQITQQNAAMVEETTAAAHALMRESEELAQRIDRFEIGDAKVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSRERQGQKRLLSVA
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MRLSISSLSIGRSISLIVLLTAVVVLTSLGFELYRTRLNLIEQKRSEIRHVVETAASIVE
CCEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAAKAKAGEMTEREAQRQALAAIDPARFDGNNYFFIYADTIRIAHPNKASIGKDFANDV
HHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEEEEECCCCCHHCHHHHHHH
DSHGKYYLRDMIATAKAGGGYVDYYFNKINDTNSYPKTSYISPIADWNWAIGAGAYMDDI
HHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
DRLFWQSSFELLLILIPLFSLLLGILFLIRKQITVLLQRLAANTKALAAGDLNVAVEAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCEEEEEECC
RSDEIGELARALQIFKDNSLTLEKTRRDNLALEASAAEERQRNEAARQKAAAYQTEVVRS
CCHHHHHHHHHHHHHCCCCCEEHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRELERIATGDMTAFIEENFSSDYAKLRDDFNISVQHMRQSIAAIQSHMRAIRSGTSEI
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
SSATDDLSRRTEQQAASLEETAAALDEITATVKKTAEGATHARDVVSTAKADADKSGAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHH
AEAIKAMGGIEQSSAQIGQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHH
ALAQRSAEAAKEIKTLIQASSTQVNQGVDLVGETGKALDRIVAQVSEINRIVAEIAASAH
HHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQATGLHQVNTAINQMDQITQQNAAMVEETTAAAHALMRESEELAQRIDRFEIGDAKVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSRERQGQKRLLSVA
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]