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The map label for this gene is caiD [C]

Identifier: 182678761

GI number: 182678761

Start: 2028430

End: 2029494

Strand: Reverse

Name: caiD [C]

Synonym: Bind_1790

Alternate gene names: 182678761

Gene position: 2029494-2028430 (Counterclockwise)

Preceding gene: 182678762

Following gene: 182678760

Centisome position: 48.67

GC content: 58.69

Gene sequence:

>1065_bases
ATGAGCGATCCTGTTATTCTGACTGAACAACAAGGTGCCTGCGGCATCATCACCTTGAACCGGCCGAAGGCGCTGAACGC
GCTCGATACGGAAACGATCCTGGTCTTCAATCAAGCCCTCGACACATTGGAGAGGGAGTCCGGCGTCAAAACAGTCGTGG
TCCGTGGTGCGGGTGGAAAAGCCTTTTGCGCCGGCGGCGATATGAAATTCATCTATGAACTCGGCAAGGCCGGGCGTCAC
GCCGAGCAATTGGATTTCTTTCGTCTCGAATACCAGCTCAACCATCGCATCGCGCGCTTCCCCAAGCCCTATGTCTCGCT
GCTCGAAGGCATTGTGATGGGGGGAGGCGCTGGCATTTCCTTGCACGCGCCGCATCGCGTGGCGGGCGAAAATTTCCTCT
TCGCCATGCCGGAAACAGCCATTGGCTTCATCCCCGATGTCGGCGCCACTTACTTCCTGCCCCGTCTTCCAGGCAAGCTC
GGCGCTTATCTCGCCATGACGGGCGCGCGCCTTGGCTGTGGCGATGGGGTGGCTTTTGGGCTCGCGACGGCCTTCATTCC
CGTAGCCCAGCATGAGGCCCTGATTGCCAAACTCGCGGCAGGCGAGGAGGCCGGCGCGGCTATCGCGATCCTCAATGCAC
CGGCACCAGAGCCTGAACTGTTCAAACTGAAACATTTCGTCGATGGTTGTTTCGGCGCGCCGACTGTCGCCGATGTTCTC
GAGGAAATCGACGAGGCCGGCTATGGCGGCCTGATGTTCGCCATGAATACTTACGATCTGATCCGGACACGATCGCCGCT
CAGTGTCACCATCGCGCTGAAACTCGCGCAGATGGGACAGAAGCTCGATCTGGAGGAGGCGTTACGGACAGAATTCCGTG
TTGTCAGCCATATTTTGCGGAGCGCCGATTTCTACGAAGGTGTGCGTGCGGTTCTTGTGGACAAGGATCACAAGCCGAAT
TGGTCGTACAAGGACATCGAGGCCTTAAAACCTGCCGATGTCGAGCCCTATTTCGCGGCCTTGCCCGAGGGTGAGGCGGA
TCTGACCTTCGCTGTCGAGGCCTAG

Upstream 100 bases:

>100_bases
CAGTCAGCCGGCCACGCTGAAAAGAATTTCACGGAAAGGTTTTGTTCAAGCATTTTCACGGCGTCGATTTTGCTCATAAT
GCGCCGCGAGTGGAGGCATT

Downstream 100 bases:

>100_bases
GGCTTATGGTGAATGGGCCGCGCCAACGGGTCTGGCCACGTTTGACGTGGCTTCGGGAGCCACATTTGCGCCTGGCGACG
CGGCCGATCGAATCCGACGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSDPVILTEQQGACGIITLNRPKALNALDTETILVFNQALDTLERESGVKTVVVRGAGGKAFCAGGDMKFIYELGKAGRH
AEQLDFFRLEYQLNHRIARFPKPYVSLLEGIVMGGGAGISLHAPHRVAGENFLFAMPETAIGFIPDVGATYFLPRLPGKL
GAYLAMTGARLGCGDGVAFGLATAFIPVAQHEALIAKLAAGEEAGAAIAILNAPAPEPELFKLKHFVDGCFGAPTVADVL
EEIDEAGYGGLMFAMNTYDLIRTRSPLSVTIALKLAQMGQKLDLEEALRTEFRVVSHILRSADFYEGVRAVLVDKDHKPN
WSYKDIEALKPADVEPYFAALPEGEADLTFAVEA

Sequences:

>Translated_354_residues
MSDPVILTEQQGACGIITLNRPKALNALDTETILVFNQALDTLERESGVKTVVVRGAGGKAFCAGGDMKFIYELGKAGRH
AEQLDFFRLEYQLNHRIARFPKPYVSLLEGIVMGGGAGISLHAPHRVAGENFLFAMPETAIGFIPDVGATYFLPRLPGKL
GAYLAMTGARLGCGDGVAFGLATAFIPVAQHEALIAKLAAGEEAGAAIAILNAPAPEPELFKLKHFVDGCFGAPTVADVL
EEIDEAGYGGLMFAMNTYDLIRTRSPLSVTIALKLAQMGQKLDLEEALRTEFRVVSHILRSADFYEGVRAVLVDKDHKPN
WSYKDIEALKPADVEPYFAALPEGEADLTFAVEA
>Mature_353_residues
SDPVILTEQQGACGIITLNRPKALNALDTETILVFNQALDTLERESGVKTVVVRGAGGKAFCAGGDMKFIYELGKAGRHA
EQLDFFRLEYQLNHRIARFPKPYVSLLEGIVMGGGAGISLHAPHRVAGENFLFAMPETAIGFIPDVGATYFLPRLPGKLG
AYLAMTGARLGCGDGVAFGLATAFIPVAQHEALIAKLAAGEEAGAAIAILNAPAPEPELFKLKHFVDGCFGAPTVADVLE
EIDEAGYGGLMFAMNTYDLIRTRSPLSVTIALKLAQMGQKLDLEEALRTEFRVVSHILRSADFYEGVRAVLVDKDHKPNW
SYKDIEALKPADVEPYFAALPEGEADLTFAVEA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=357, Percent_Identity=41.1764705882353, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI37594469, Length=301, Percent_Identity=41.1960132890365, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI194097323, Length=189, Percent_Identity=35.978835978836, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI221142681, Length=191, Percent_Identity=30.8900523560209, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787659, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787660, Length=179, Percent_Identity=30.1675977653631, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788597, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790281, Length=172, Percent_Identity=25.5813953488372, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=349, Percent_Identity=37.5358166189112, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI25144160, Length=349, Percent_Identity=37.5358166189112, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI25145438, Length=177, Percent_Identity=35.0282485875706, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=177, Percent_Identity=29.9435028248588, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=156, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=156, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=156, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=28.4153005464481, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=359, Percent_Identity=31.1977715877437, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571729, Length=348, Percent_Identity=37.6436781609195, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI28571730, Length=348, Percent_Identity=37.6436781609195, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI20129971, Length=177, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24653477, Length=177, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24653139, Length=142, Percent_Identity=30.9859154929577, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 38067; Mature: 37936

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPVILTEQQGACGIITLNRPKALNALDTETILVFNQALDTLERESGVKTVVVRGAGGK
CCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCC
AFCAGGDMKFIYELGKAGRHAEQLDFFRLEYQLNHRIARFPKPYVSLLEGIVMGGGAGIS
EEECCCCHHHHHHHHHCCCCHHHHHHEEEEEHHCCHHHHCCCHHHHHHHHHHCCCCCCEE
LHAPHRVAGENFLFAMPETAIGFIPDVGATYFLPRLPGKLGAYLAMTGARLGCGDGVAFG
EECCCCCCCCCEEEECCCHHHCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHH
LATAFIPVAQHEALIAKLAAGEEAGAAIAILNAPAPEPELFKLKHFVDGCFGAPTVADVL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHH
EEIDEAGYGGLMFAMNTYDLIRTRSPLSVTIALKLAQMGQKLDLEEALRTEFRVVSHILR
HHHHHCCCCCEEEEECHHHHHHCCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHH
SADFYEGVRAVLVDKDHKPNWSYKDIEALKPADVEPYFAALPEGEADLTFAVEA
CCHHHHHHEEEEEECCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SDPVILTEQQGACGIITLNRPKALNALDTETILVFNQALDTLERESGVKTVVVRGAGGK
CCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCC
AFCAGGDMKFIYELGKAGRHAEQLDFFRLEYQLNHRIARFPKPYVSLLEGIVMGGGAGIS
EEECCCCHHHHHHHHHCCCCHHHHHHEEEEEHHCCHHHHCCCHHHHHHHHHHCCCCCCEE
LHAPHRVAGENFLFAMPETAIGFIPDVGATYFLPRLPGKLGAYLAMTGARLGCGDGVAFG
EECCCCCCCCCEEEECCCHHHCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHH
LATAFIPVAQHEALIAKLAAGEEAGAAIAILNAPAPEPELFKLKHFVDGCFGAPTVADVL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHH
EEIDEAGYGGLMFAMNTYDLIRTRSPLSVTIALKLAQMGQKLDLEEALRTEFRVVSHILR
HHHHHCCCCCEEEEECHHHHHHCCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHH
SADFYEGVRAVLVDKDHKPNWSYKDIEALKPADVEPYFAALPEGEADLTFAVEA
CCHHHHHHEEEEEECCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA