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The map label for this gene is pcm [H]

Identifier: 182678699

GI number: 182678699

Start: 1954038

End: 1954775

Strand: Reverse

Name: pcm [H]

Synonym: Bind_1726

Alternate gene names: 182678699

Gene position: 1954775-1954038 (Counterclockwise)

Preceding gene: 182678705

Following gene: 182678698

Centisome position: 46.88

GC content: 60.43

Gene sequence:

>738_bases
ATGCCAGCCACTTCCCTGGCCGAACCTGTCTCCCCCATCGCTCCGGCTGGTGGGGACCAATCGGCTTTCTTGCGCCAGAC
CATGGTCGATTGCCAGGTGCGGACGTTCGATGTCACCGACCAGCGGCTTCTTGAAAGAATGCTCGAGGTCCCGCGCGAGA
GTTTCCTGCCGGCTTCCCTGGCCCCGGTCGCTTATTCGGATAAGGTTTTGCGTCTAGCCCCGACGCATCCGGCTGGCGCT
GAGCGTCACTTGTTGCCGCCCCTGATTCTTGCCCGTCTCATCCAGGGCGCGCAGGTCACGCCCAACGACCATGTTCTCGA
TATTGCGTCGGGCTCTGGCTATTCCACGGCGCTTCTCGCCGGCCTTGCCCATGATGTCGTGGCGCTTGAATCCGAACCGG
AATGGGCCGCTTTCACCCGTAACGCCATCGCGGCTCATGGCCTTCAGACGGTATCCGTCGTCGAGGGGCCGCTAGCGGAA
GGTGTACCCGCACAAGCTCCGTTCGATTTGATTCTCATCAATGGTGCCGTCGAAGCCCAACTCGAAACCCTCTTTGCGCA
ATTGCAGGAGGGAGGCCGTCTCCTGGCTCTCACTTACGAGGAGAACGACCCGACCAAGCGCGCGGGCAAGGCGGTTCGAT
TCGAGAAAATCGGCGGCGAAATCAGCCAACGCACGCTGTTTGATTTTTCTCTTCCAGTCCTTGAGGCCTTTGCGCGCGCG
GAACAGTTCAAATTCTAG

Upstream 100 bases:

>100_bases
TCTCTTCGCCAAGGTGCCGAAACCTGCCTGTTGGTCCTACCTCGTCGATCCTGCTGTCTTGATCCTTGGGTCATTGATCT
CGCCGCTACAGGAGTTTTTC

Downstream 100 bases:

>100_bases
AATGTCTTCCCGATTTGTTGAATCGGGAAAAGATTTTGTCCGTTGAATGAGCGTGTTTTCAAGACCGGAGTGAAGAGGCT
TCGTTTGAAAATGCGCTCTT

Product: protein-L-isoaspartate(D-aspartate) O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPATSLAEPVSPIAPAGGDQSAFLRQTMVDCQVRTFDVTDQRLLERMLEVPRESFLPASLAPVAYSDKVLRLAPTHPAGA
ERHLLPPLILARLIQGAQVTPNDHVLDIASGSGYSTALLAGLAHDVVALESEPEWAAFTRNAIAAHGLQTVSVVEGPLAE
GVPAQAPFDLILINGAVEAQLETLFAQLQEGGRLLALTYEENDPTKRAGKAVRFEKIGGEISQRTLFDFSLPVLEAFARA
EQFKF

Sequences:

>Translated_245_residues
MPATSLAEPVSPIAPAGGDQSAFLRQTMVDCQVRTFDVTDQRLLERMLEVPRESFLPASLAPVAYSDKVLRLAPTHPAGA
ERHLLPPLILARLIQGAQVTPNDHVLDIASGSGYSTALLAGLAHDVVALESEPEWAAFTRNAIAAHGLQTVSVVEGPLAE
GVPAQAPFDLILINGAVEAQLETLFAQLQEGGRLLALTYEENDPTKRAGKAVRFEKIGGEISQRTLFDFSLPVLEAFARA
EQFKF
>Mature_244_residues
PATSLAEPVSPIAPAGGDQSAFLRQTMVDCQVRTFDVTDQRLLERMLEVPRESFLPASLAPVAYSDKVLRLAPTHPAGAE
RHLLPPLILARLIQGAQVTPNDHVLDIASGSGYSTALLAGLAHDVVALESEPEWAAFTRNAIAAHGLQTVSVVEGPLAEG
VPAQAPFDLILINGAVEAQLETLFAQLQEGGRLLALTYEENDPTKRAGKAVRFEKIGGEISQRTLFDFSLPVLEAFARAE
QFKF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=187, Percent_Identity=32.0855614973262, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 26330; Mature: 26199

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATSLAEPVSPIAPAGGDQSAFLRQTMVDCQVRTFDVTDQRLLERMLEVPRESFLPASL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHCCHHHCCCCCC
APVAYSDKVLRLAPTHPAGAERHLLPPLILARLIQGAQVTPNDHVLDIASGSGYSTALLA
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHH
GLAHDVVALESEPEWAAFTRNAIAAHGLQTVSVVEGPLAEGVPAQAPFDLILINGAVEAQ
HHHHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCHHCCCCCCCCEEEEEECCHHHHH
LETLFAQLQEGGRLLALTYEENDPTKRAGKAVRFEKIGGEISQRTLFDFSLPVLEAFARA
HHHHHHHHHCCCEEEEEEECCCCCHHHHCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHH
EQFKF
HHCCC
>Mature Secondary Structure 
PATSLAEPVSPIAPAGGDQSAFLRQTMVDCQVRTFDVTDQRLLERMLEVPRESFLPASL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHCCHHHCCCCCC
APVAYSDKVLRLAPTHPAGAERHLLPPLILARLIQGAQVTPNDHVLDIASGSGYSTALLA
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHH
GLAHDVVALESEPEWAAFTRNAIAAHGLQTVSVVEGPLAEGVPAQAPFDLILINGAVEAQ
HHHHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCHHCCCCCCCCEEEEEECCHHHHH
LETLFAQLQEGGRLLALTYEENDPTKRAGKAVRFEKIGGEISQRTLFDFSLPVLEAFARA
HHHHHHHHHCCCEEEEEEECCCCCHHHHCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHH
EQFKF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA