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The map label for this gene is yfnA [H]

Identifier: 182678637

GI number: 182678637

Start: 1880458

End: 1881948

Strand: Reverse

Name: yfnA [H]

Synonym: Bind_1663

Alternate gene names: 182678637

Gene position: 1881948-1880458 (Counterclockwise)

Preceding gene: 182678641

Following gene: 182678634

Centisome position: 45.13

GC content: 56.14

Gene sequence:

>1491_bases
ATGAGCAATATATGGGTGCGCAAATCCATGGCCGTGCTAAAGGCCGAGGCGCAGGATGAACTGACTGGGACCGAGGGTTT
GCACCGCTCCATGTCGCTCTTCAGCCTTGTGTCGTTTGGCATTGGCGGCATTATCGGTGCGGGTATTTTCGTTTTGACCG
GCCATGCGGCGGCATCCTATGCCGGACCAGCGATCAGTCTGTCCTTTGTGCTCGCGGGGCTCGTCTGTCTCTTCGCTGGC
CTCTGTTACGCGGAAATGGCCTCAACTGTTCCCATTGCCGGCAGCGCCTATACTTATGCCTATGCGACGATGGGAGAATT
GATCGCCTGGATCATCGGCTGGGATCTCGTGCTCGAATATTCCGTCGCCTCGGCAACGGTGGCAATTGGCTGGTCCGGCT
ATGCCACGAGCCTGCTCGCTGGTTTCGGTCTGAAAATTCCGGAAAATTTGACGAGCGCGCCTTTTACCTATGATCCAGCG
ACAGGTGACTGGACCCATACAGGCGCTCTGGTCAATCTGCCGGCCCTTTTCATCATCCTGTTCATGACGGTCTTGCTCGT
TTTGGGTGTCCGGGAATCGGCGCGGGTCAATAATGTCATCGTGCTGATCAAGCTCTCCATCGTCATTTTGTTCATCGCGG
TCGGACTCGGTTCGGTATCTCTGGCGAATTGGGTGACGCCCGGCAATCCCGAGGGCCTCTATATTCCACCGACAACAGGC
GTCGGCCAATTCGGCTGGAGCGGGGTCGTTCGTGGCGCGGCCGTGGTGTTTTTCGCCTATATCGGCTTCGATGCTGTTTC
GACCGCGGCGCAGGAGGCCCATGATCCACAAAGGACATTGCCGATCGGAATTCTCGGCTCGCTGCTCTTTTGTACCCTGC
TTTATGTTCTCGTCAGCTTCGTCATCACCGGCATCGTGCCCTATGATCAATTGAACGTTCCAGATCCGATCGCGCTTGGC
GTGGATACGATCGGCCTCGGCTGGTTCTCGGCCTTGATCAAGCTTGGCGCGGTCCTCGGTTTGAGTTCCGTCATTCTCGT
TTTTCTCTTCGGCCAGCCGCGCATCTTCTATGCAATGGCGAAGGACGGTCTTTTGCCACCTTTCGCGGCGAAAGTGCATC
CGCGTTTTCATACCCCCTATATCACCACCATCATCACTGGCATCGGCATCGCCGTGATTTCGGCTCTGCTACCGATCGGG
CTCGTCGGTGAATTGGTCAGCATCGGGACGCTTTTCGCCTTTGCTGTCGTTTGCGGTGGTGTCCTGATCCTGCGGATCAC
GCATCCGGAAATTCACCGGCCTTTCAAGACTCCGGCGGTTTATATCGTCGCGCCTCTTGGTGTGTTTTCAGCCCTATTTT
TGATGTTTGGCCTGCCTAATGATACCTGGGTCCGGCTCGTCGTTTGGCTGTTCATCGGGCTCGTCATTTACTTCTTCTAT
GGACGCAAACACAGTGTGATCCAGCGTGCCGCGCAAGAGTCCGAGAAATGA

Upstream 100 bases:

>100_bases
TCTTGAGCGGACGCTGCGACAAAGGAGGGAAACATTTTCCCGAGCGGGAAAAAGGGAGGATAGTCAGGCTTCGGCTGGCT
GACACGTTGGAGTGGCATGC

Downstream 100 bases:

>100_bases
AATGATTTCAAGGCTGGCGGGAAAATCAGGCGTCTCCTCCGACGACACTCATCCAGCCTCGTCATCAGATTGCTTTTGAT
TGTCAGACGCGGACACAAAC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSNIWVRKSMAVLKAEAQDELTGTEGLHRSMSLFSLVSFGIGGIIGAGIFVLTGHAAASYAGPAISLSFVLAGLVCLFAG
LCYAEMASTVPIAGSAYTYAYATMGELIAWIIGWDLVLEYSVASATVAIGWSGYATSLLAGFGLKIPENLTSAPFTYDPA
TGDWTHTGALVNLPALFIILFMTVLLVLGVRESARVNNVIVLIKLSIVILFIAVGLGSVSLANWVTPGNPEGLYIPPTTG
VGQFGWSGVVRGAAVVFFAYIGFDAVSTAAQEAHDPQRTLPIGILGSLLFCTLLYVLVSFVITGIVPYDQLNVPDPIALG
VDTIGLGWFSALIKLGAVLGLSSVILVFLFGQPRIFYAMAKDGLLPPFAAKVHPRFHTPYITTIITGIGIAVISALLPIG
LVGELVSIGTLFAFAVVCGGVLILRITHPEIHRPFKTPAVYIVAPLGVFSALFLMFGLPNDTWVRLVVWLFIGLVIYFFY
GRKHSVIQRAAQESEK

Sequences:

>Translated_496_residues
MSNIWVRKSMAVLKAEAQDELTGTEGLHRSMSLFSLVSFGIGGIIGAGIFVLTGHAAASYAGPAISLSFVLAGLVCLFAG
LCYAEMASTVPIAGSAYTYAYATMGELIAWIIGWDLVLEYSVASATVAIGWSGYATSLLAGFGLKIPENLTSAPFTYDPA
TGDWTHTGALVNLPALFIILFMTVLLVLGVRESARVNNVIVLIKLSIVILFIAVGLGSVSLANWVTPGNPEGLYIPPTTG
VGQFGWSGVVRGAAVVFFAYIGFDAVSTAAQEAHDPQRTLPIGILGSLLFCTLLYVLVSFVITGIVPYDQLNVPDPIALG
VDTIGLGWFSALIKLGAVLGLSSVILVFLFGQPRIFYAMAKDGLLPPFAAKVHPRFHTPYITTIITGIGIAVISALLPIG
LVGELVSIGTLFAFAVVCGGVLILRITHPEIHRPFKTPAVYIVAPLGVFSALFLMFGLPNDTWVRLVVWLFIGLVIYFFY
GRKHSVIQRAAQESEK
>Mature_495_residues
SNIWVRKSMAVLKAEAQDELTGTEGLHRSMSLFSLVSFGIGGIIGAGIFVLTGHAAASYAGPAISLSFVLAGLVCLFAGL
CYAEMASTVPIAGSAYTYAYATMGELIAWIIGWDLVLEYSVASATVAIGWSGYATSLLAGFGLKIPENLTSAPFTYDPAT
GDWTHTGALVNLPALFIILFMTVLLVLGVRESARVNNVIVLIKLSIVILFIAVGLGSVSLANWVTPGNPEGLYIPPTTGV
GQFGWSGVVRGAAVVFFAYIGFDAVSTAAQEAHDPQRTLPIGILGSLLFCTLLYVLVSFVITGIVPYDQLNVPDPIALGV
DTIGLGWFSALIKLGAVLGLSSVILVFLFGQPRIFYAMAKDGLLPPFAAKVHPRFHTPYITTIITGIGIAVISALLPIGL
VGELVSIGTLFAFAVVCGGVLILRITHPEIHRPFKTPAVYIVAPLGVFSALFLMFGLPNDTWVRLVVWLFIGLVIYFFYG
RKHSVIQRAAQESEK

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=437, Percent_Identity=34.5537757437071, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI4507047, Length=449, Percent_Identity=35.4120267260579, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI258614003, Length=437, Percent_Identity=34.5537757437071, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI258645169, Length=437, Percent_Identity=34.7826086956522, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI114326544, Length=413, Percent_Identity=35.3510895883777, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI114326550, Length=413, Percent_Identity=35.3510895883777, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI181337167, Length=410, Percent_Identity=34.8780487804878, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI110347453, Length=421, Percent_Identity=34.6793349168646, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI33286428, Length=440, Percent_Identity=23.8636363636364, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657683, Length=407, Percent_Identity=24.0786240786241, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115648063, Length=423, Percent_Identity=24.3498817966903, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI115648022, Length=423, Percent_Identity=24.3498817966903, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI187423910, Length=501, Percent_Identity=24.3512974051896, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI7657591, Length=501, Percent_Identity=24.3512974051896, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI71979932, Length=464, Percent_Identity=24.3534482758621, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI186910308, Length=412, Percent_Identity=23.0582524271845, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910306, Length=412, Percent_Identity=23.0582524271845, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910304, Length=412, Percent_Identity=23.0582524271845, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI9790235, Length=440, Percent_Identity=25, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI87082250, Length=485, Percent_Identity=26.1855670103093, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081869, Length=449, Percent_Identity=23.162583518931, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082023, Length=441, Percent_Identity=23.3560090702948, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788480, Length=395, Percent_Identity=26.5822784810127, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790653, Length=488, Percent_Identity=21.9262295081967, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786602, Length=491, Percent_Identity=23.0142566191446, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081915, Length=409, Percent_Identity=25.9168704156479, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081708, Length=494, Percent_Identity=21.2550607287449, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI48994972, Length=379, Percent_Identity=24.5382585751979, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786694, Length=478, Percent_Identity=25.3138075313808, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786789, Length=432, Percent_Identity=22.6851851851852, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789017, Length=357, Percent_Identity=23.249299719888, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI2367353, Length=418, Percent_Identity=27.0334928229665, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=402, Percent_Identity=36.0696517412935, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17531343, Length=433, Percent_Identity=33.4872979214781, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=31.6301703163017, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17540018, Length=477, Percent_Identity=26.6247379454927, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32566699, Length=380, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=440, Percent_Identity=24.5454545454545, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71993915, Length=358, Percent_Identity=24.3016759776536, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537453, Length=369, Percent_Identity=21.680216802168, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71995388, Length=361, Percent_Identity=24.6537396121884, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=361, Percent_Identity=24.6537396121884, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=36.1948955916473, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=36.1948955916473, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24668806, Length=445, Percent_Identity=35.0561797752809, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21356285, Length=445, Percent_Identity=35.0561797752809, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24668802, Length=445, Percent_Identity=35.0561797752809, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24667468, Length=415, Percent_Identity=35.421686746988, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI281366235, Length=419, Percent_Identity=34.8448687350835, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI116007820, Length=419, Percent_Identity=34.8448687350835, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI116007818, Length=424, Percent_Identity=35.377358490566, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI85725152, Length=424, Percent_Identity=35.377358490566, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI161077963, Length=400, Percent_Identity=34.25, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21357367, Length=440, Percent_Identity=23.6363636363636, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221331183, Length=458, Percent_Identity=24.0174672489083, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17647653, Length=458, Percent_Identity=24.0174672489083, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24664379, Length=458, Percent_Identity=24.0174672489083, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550968, Length=449, Percent_Identity=25.3897550111359, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19921172, Length=449, Percent_Identity=25.3897550111359, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24651635, Length=457, Percent_Identity=24.945295404814, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651633, Length=457, Percent_Identity=24.945295404814, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52707; Mature: 52576

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIWVRKSMAVLKAEAQDELTGTEGLHRSMSLFSLVSFGIGGIIGAGIFVLTGHAAASY
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHH
AGPAISLSFVLAGLVCLFAGLCYAEMASTVPIAGSAYTYAYATMGELIAWIIGWDLVLEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVASATVAIGWSGYATSLLAGFGLKIPENLTSAPFTYDPATGDWTHTGALVNLPALFIIL
HHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHH
FMTVLLVLGVRESARVNNVIVLIKLSIVILFIAVGLGSVSLANWVTPGNPEGLYIPPTTG
HHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCC
VGQFGWSGVVRGAAVVFFAYIGFDAVSTAAQEAHDPQRTLPIGILGSLLFCTLLYVLVSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VITGIVPYDQLNVPDPIALGVDTIGLGWFSALIKLGAVLGLSSVILVFLFGQPRIFYAMA
HHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
KDGLLPPFAAKVHPRFHTPYITTIITGIGIAVISALLPIGLVGELVSIGTLFAFAVVCGG
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLILRITHPEIHRPFKTPAVYIVAPLGVFSALFLMFGLPNDTWVRLVVWLFIGLVIYFFY
EEEEEECCHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GRKHSVIQRAAQESEK
CCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNIWVRKSMAVLKAEAQDELTGTEGLHRSMSLFSLVSFGIGGIIGAGIFVLTGHAAASY
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHH
AGPAISLSFVLAGLVCLFAGLCYAEMASTVPIAGSAYTYAYATMGELIAWIIGWDLVLEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVASATVAIGWSGYATSLLAGFGLKIPENLTSAPFTYDPATGDWTHTGALVNLPALFIIL
HHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHH
FMTVLLVLGVRESARVNNVIVLIKLSIVILFIAVGLGSVSLANWVTPGNPEGLYIPPTTG
HHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCC
VGQFGWSGVVRGAAVVFFAYIGFDAVSTAAQEAHDPQRTLPIGILGSLLFCTLLYVLVSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VITGIVPYDQLNVPDPIALGVDTIGLGWFSALIKLGAVLGLSSVILVFLFGQPRIFYAMA
HHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
KDGLLPPFAAKVHPRFHTPYITTIITGIGIAVISALLPIGLVGELVSIGTLFAFAVVCGG
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLILRITHPEIHRPFKTPAVYIVAPLGVFSALFLMFGLPNDTWVRLVVWLFIGLVIYFFY
EEEEEECCHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GRKHSVIQRAAQESEK
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]