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The map label for this gene is yfdZ [C]

Identifier: 182678634

GI number: 182678634

Start: 1876615

End: 1877787

Strand: Reverse

Name: yfdZ [C]

Synonym: Bind_1660

Alternate gene names: 182678634

Gene position: 1877787-1876615 (Counterclockwise)

Preceding gene: 182678637

Following gene: 182678633

Centisome position: 45.03

GC content: 60.61

Gene sequence:

>1173_bases
ATGATGACAGGCTTGAGGGAGCGTATTTCTTCCACCCGCTCCGCCATGGCTCCGTTTCTTGCCCTCGATATTCTTAACCA
GGCTACCCAGCGCGAGCGGGAGGGTGAGAATATCGTCCATATGGAAGTCGGCGAGCCGGGGGCTACGACGCCCACCGTGG
TGCGCCAGGCCGTGCAGGAAGCCCTTGCCATCGGTCGCGTCGGCTATACGGAAGCCCTCGGCCGCCCGAGCCTGCGCGCC
CGCATCGCTCGTCATTATCAAGAGACCTATGGCGTCACCATCGCACCCGAGCGCGTCGCCGTGACGATTGGTTCCTCCGG
CGGCTTCATGCTGGCCTTTCTCGCCGCCTTCGATGCCGGCGCGCGGATCGGCGTGCAAGCGCCGGGTTATCCCGCTTATC
GCAATATTTTCGACGCCCTCGGACTCGAGACCGTCGTGATCGAGACCAATGCCTCGACCCGTCATGTCGTCACGCCGGAT
ATGATCGAGGCCGCCCATGCGGAGCGTCCCCTCGACGGTCTTTTGCTGATGAGCCCAGCCAATCCGACCGGCACGATGAT
GAGCCCCGAGGACCTGCAAGCGGTCTGCGCGGTTTGCGACCGGCTCGGCATCACCTTCATTTCGGACGAAGTCTATCATG
GCTTGACCTATCTCGAGCCGGCCGAGACAGCGCTGAAATTCTCGGACCGGGTCATCGTCGCCAATTCCTTCTCCAAATAT
TATTGCATGACGGGCTGGCGCGTCGGCTGGCTCATTCTGCCCGAAGCCCTGATGCGCCCGGTCGAACGGTTGCAGCAGAA
TCTAGCAATTTCCGTGCCTTATTTGAGCCAGGTCGCGGCGGAGGCCGCTTTCGATGCCAAGGATGAGTTGCAACTCATCA
AGGCAGGTTATGCCGCCAATAGAAGCTTTTTGCTGCGATCCTTGCCACAGGTCGGCCTTGCCGATTTCCATCCTGTCGAT
GGGGCCTTTTACATCTATGCGGATGTGTCTCGTTTCACCAATGATTCCCTGGAATTCTCCCGCCGCATGCTGGACGAGAC
GGGCGTGGCGGTGACGCCCGGCCTGGATTTCGACCGCAATCGAGGCAATAGTTTCATTCGCCTGTCTTTTGCCGGGCCAG
AGCGGGACATGGTCGAGGCGGTTTCTCGCCTTGGCCTCTGGCTTCCGTCTTGA

Upstream 100 bases:

>100_bases
GGGTTGGAAAATTTCCGGTCGCGACGAACCAAGGATCGCAAGGAGCGGTCCGGGGTCATCTTTCCATTGACCCATGACAG
AACATGACGAAAGGTCAGCA

Downstream 100 bases:

>100_bases
AACCAGCCCCGATCTGATGACAGGATTGAGAACCAGACATCGGCGCCAGCCATAGGAGGCAGACTCTGAAAGCGAGGTTC
TTCTTGTGTCGTCAGCATCT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MMTGLRERISSTRSAMAPFLALDILNQATQREREGENIVHMEVGEPGATTPTVVRQAVQEALAIGRVGYTEALGRPSLRA
RIARHYQETYGVTIAPERVAVTIGSSGGFMLAFLAAFDAGARIGVQAPGYPAYRNIFDALGLETVVIETNASTRHVVTPD
MIEAAHAERPLDGLLLMSPANPTGTMMSPEDLQAVCAVCDRLGITFISDEVYHGLTYLEPAETALKFSDRVIVANSFSKY
YCMTGWRVGWLILPEALMRPVERLQQNLAISVPYLSQVAAEAAFDAKDELQLIKAGYAANRSFLLRSLPQVGLADFHPVD
GAFYIYADVSRFTNDSLEFSRRMLDETGVAVTPGLDFDRNRGNSFIRLSFAGPERDMVEAVSRLGLWLPS

Sequences:

>Translated_390_residues
MMTGLRERISSTRSAMAPFLALDILNQATQREREGENIVHMEVGEPGATTPTVVRQAVQEALAIGRVGYTEALGRPSLRA
RIARHYQETYGVTIAPERVAVTIGSSGGFMLAFLAAFDAGARIGVQAPGYPAYRNIFDALGLETVVIETNASTRHVVTPD
MIEAAHAERPLDGLLLMSPANPTGTMMSPEDLQAVCAVCDRLGITFISDEVYHGLTYLEPAETALKFSDRVIVANSFSKY
YCMTGWRVGWLILPEALMRPVERLQQNLAISVPYLSQVAAEAAFDAKDELQLIKAGYAANRSFLLRSLPQVGLADFHPVD
GAFYIYADVSRFTNDSLEFSRRMLDETGVAVTPGLDFDRNRGNSFIRLSFAGPERDMVEAVSRLGLWLPS
>Mature_390_residues
MMTGLRERISSTRSAMAPFLALDILNQATQREREGENIVHMEVGEPGATTPTVVRQAVQEALAIGRVGYTEALGRPSLRA
RIARHYQETYGVTIAPERVAVTIGSSGGFMLAFLAAFDAGARIGVQAPGYPAYRNIFDALGLETVVIETNASTRHVVTPD
MIEAAHAERPLDGLLLMSPANPTGTMMSPEDLQAVCAVCDRLGITFISDEVYHGLTYLEPAETALKFSDRVIVANSFSKY
YCMTGWRVGWLILPEALMRPVERLQQNLAISVPYLSQVAAEAAFDAKDELQLIKAGYAANRSFLLRSLPQVGLADFHPVD
GAFYIYADVSRFTNDSLEFSRRMLDETGVAVTPGLDFDRNRGNSFIRLSFAGPERDMVEAVSRLGLWLPS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=349, Percent_Identity=26.3610315186246, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI169881279, Length=349, Percent_Identity=26.3610315186246, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=24.8717948717949, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=24.8717948717949, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4507369, Length=418, Percent_Identity=24.4019138755981, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=24.6913580246914, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788722, Length=355, Percent_Identity=28.7323943661972, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=25.7978723404255, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788627, Length=236, Percent_Identity=25.8474576271186, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=329, Percent_Identity=27.0516717325228, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790797, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=342, Percent_Identity=24.5614035087719, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=342, Percent_Identity=24.5614035087719, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=379, Percent_Identity=23.2189973614776, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=21.7948717948718, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573069, Length=360, Percent_Identity=21.3888888888889, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646114, Length=360, Percent_Identity=21.3888888888889, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573067, Length=360, Percent_Identity=21.3888888888889, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573065, Length=360, Percent_Identity=21.3888888888889, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI18859735, Length=356, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42716; Mature: 42716

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTGLRERISSTRSAMAPFLALDILNQATQREREGENIVHMEVGEPGATTPTVVRQAVQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
ALAIGRVGYTEALGRPSLRARIARHYQETYGVTIAPERVAVTIGSSGGFMLAFLAAFDAG
HHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHCCC
ARIGVQAPGYPAYRNIFDALGLETVVIETNASTRHVVTPDMIEAAHAERPLDGLLLMSPA
CEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHHHCCCCCCEEEECCC
NPTGTMMSPEDLQAVCAVCDRLGITFISDEVYHGLTYLEPAETALKFSDRVIVANSFSKY
CCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCE
YCMTGWRVGWLILPEALMRPVERLQQNLAISVPYLSQVAAEAAFDAKDELQLIKAGYAAN
EEECCCEEHHEECCHHHHHHHHHHHHCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RSFLLRSLPQVGLADFHPVDGAFYIYADVSRFTNDSLEFSRRMLDETGVAVTPGLDFDRN
HHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCC
RGNSFIRLSFAGPERDMVEAVSRLGLWLPS
CCCCEEEEEECCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMTGLRERISSTRSAMAPFLALDILNQATQREREGENIVHMEVGEPGATTPTVVRQAVQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
ALAIGRVGYTEALGRPSLRARIARHYQETYGVTIAPERVAVTIGSSGGFMLAFLAAFDAG
HHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHCCC
ARIGVQAPGYPAYRNIFDALGLETVVIETNASTRHVVTPDMIEAAHAERPLDGLLLMSPA
CEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHHHCCCCCCEEEECCC
NPTGTMMSPEDLQAVCAVCDRLGITFISDEVYHGLTYLEPAETALKFSDRVIVANSFSKY
CCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCE
YCMTGWRVGWLILPEALMRPVERLQQNLAISVPYLSQVAAEAAFDAKDELQLIKAGYAAN
EEECCCEEHHEECCHHHHHHHHHHHHCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RSFLLRSLPQVGLADFHPVDGAFYIYADVSRFTNDSLEFSRRMLDETGVAVTPGLDFDRN
HHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCC
RGNSFIRLSFAGPERDMVEAVSRLGLWLPS
CCCCEEEEEECCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]