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The map label for this gene is xpsE [H]

Identifier: 182678561

GI number: 182678561

Start: 1786460

End: 1788076

Strand: Reverse

Name: xpsE [H]

Synonym: Bind_1586

Alternate gene names: 182678561

Gene position: 1788076-1786460 (Counterclockwise)

Preceding gene: 182678570

Following gene: 182678560

Centisome position: 42.88

GC content: 61.04

Gene sequence:

>1617_bases
ATGAAGCCATTGATGGACGTCGACAAAACCAGTGATTTGGCTCTGCCCGTTTCGGGAACGGATGTAGCGGACGGCGATCT
GACCTTATCCATTCCGGATGAAGGTTCCGACCCGCCTCGCATAAGTCTAGCCATGATGCAGGCGGCCTCTTCATTGGCTG
GGCAATTTTCCCAGGTTTTTTTGCGCGAGTCGGGGCTTTTTCCTTTTCGGGCGGAAAATGGCGCCATTTGGATCGCCGCC
GCTGATCCAAACCGACCGGAACCCATTGATGCCCTGCGGCTGACGCTTGCCGGTGACATCGCCATTGCGACGGCGGCCCG
CGAGGATATTGAAACAATTCTCGATCTCGTATCGACGCGGGAAACGGAGACGGAAGCCCAGGCCGGAGATAGCCAGAGCC
CGGATGTGACCGCCGAGGATGCCGAAAGCTTGCGTGATCTCGCAAGCGGCGCCCCCGTCGTGCAGGCTCTCGAACAGATT
TTTGAACGTGCCGTGACCTGGCGCGGGACCGACATTCATATCGAACCTCTCAAACGCGAGCTTCGTGTCCGCATCCGCGT
GGATGGCATCCTGCGATTGATGCCCGTTCCTCAAAACGTTTCCGCTCGCGCGCTCGTCTCGCGGGTGAAAATCCTAAGCG
GCCTGAACATCGCCGAACACCGCTTGCCCCAGGATGGACGCGCCCGCATGCAAGTGCGCGGGCGCGAATTCGACCTCCGC
GTGGCGACCATGCCGACCATGGGCGGAGAAGCCGCCATTCTGCGTCTGCTCGAGCGCAATTCCACGCTCGTCGCCTTCGG
CAAAATCGGCTTCAGTCCACGCGATGAAGCCGTGTTGCGCCGGCAACTCGGGCGGCCGCATGGTCTGCTGATCGTCACGG
GGCCGACGGGAAGCGGCAAGACGACCACGCTTGCCGCCAGTATTGCGGAAATGAATGACACGAGCCGCAAAATCCTGACG
ATCGAGGATCCGGTCGAATATGAGCTCCCCGGCGTCAGCCAGTCTCAAGTTCGCTCCGCGATCGGTTTGACCTTCGCCAA
CGCCCTGCGCGCGTTCCTGCGTCAGGATCCCGATGTCATCATGGTCGGCGAAATCCGCGATGGCGAAACCGCCAGCATCG
CCATGCAAGCGTCTCTGACCGGCCATCTTGTGCTCAGTACCCTGCATACGAATAGCGCGGCGGCGGCGCTCAATCGCCTC
ACCGATCTGGGGATCGAACCCTTTCTCGTCGCGTCCACTTTGACCACTGTGGTGGCCCAGCGTCTCGCACGCAATCTTTG
TCCCGATTGCAAGAAACCGGCGGCCGTGACACAGCAAGATCTCGAGGAGGACCCCCGTCTCACGGCCTTCGGCTTCGAGA
TCGGTACCATCCTGCACCACGCGGTGGGTTGCGAGCGTTGTGCTCATACCGGCTATCGCGGGCGTGGCGCCTTATTCGAG
GTGCTGGAAATCACCGACGAGATTCGGCGGCTGATCTTGAATGGAGCGGATGAGGGTATCATCGTTCAGACGGCCCGGAC
GCAGGGCATGCAGACCATGCTGGACGACGGTCTCGCCCGCTGCCGCCTGGGTCAAACGACGATCGACGAAGTTTTCCGCG
TCGTCGCGCAATCCTGA

Upstream 100 bases:

>100_bases
GATGATAATATCGATTCCTGGCCAAGGATAGCATTCTCCGCTGGGTAACAGTGGAGAATGAGCCGGGCTCTGTCCTATAT
TTTTGCAAAATGTCAAACTT

Downstream 100 bases:

>100_bases
TTTCGTTCTGGCCTGATTTTCTGTTCTGAAAAGAGCCATAAGGGTAAAGGAGAATTACGCTGGCTTCCTGGACCGCCCAT
GAGCCAGGCTCTGACACTCC

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKPLMDVDKTSDLALPVSGTDVADGDLTLSIPDEGSDPPRISLAMMQAASSLAGQFSQVFLRESGLFPFRAENGAIWIAA
ADPNRPEPIDALRLTLAGDIAIATAAREDIETILDLVSTRETETEAQAGDSQSPDVTAEDAESLRDLASGAPVVQALEQI
FERAVTWRGTDIHIEPLKRELRVRIRVDGILRLMPVPQNVSARALVSRVKILSGLNIAEHRLPQDGRARMQVRGREFDLR
VATMPTMGGEAAILRLLERNSTLVAFGKIGFSPRDEAVLRRQLGRPHGLLIVTGPTGSGKTTTLAASIAEMNDTSRKILT
IEDPVEYELPGVSQSQVRSAIGLTFANALRAFLRQDPDVIMVGEIRDGETASIAMQASLTGHLVLSTLHTNSAAAALNRL
TDLGIEPFLVASTLTTVVAQRLARNLCPDCKKPAAVTQQDLEEDPRLTAFGFEIGTILHHAVGCERCAHTGYRGRGALFE
VLEITDEIRRLILNGADEGIIVQTARTQGMQTMLDDGLARCRLGQTTIDEVFRVVAQS

Sequences:

>Translated_538_residues
MKPLMDVDKTSDLALPVSGTDVADGDLTLSIPDEGSDPPRISLAMMQAASSLAGQFSQVFLRESGLFPFRAENGAIWIAA
ADPNRPEPIDALRLTLAGDIAIATAAREDIETILDLVSTRETETEAQAGDSQSPDVTAEDAESLRDLASGAPVVQALEQI
FERAVTWRGTDIHIEPLKRELRVRIRVDGILRLMPVPQNVSARALVSRVKILSGLNIAEHRLPQDGRARMQVRGREFDLR
VATMPTMGGEAAILRLLERNSTLVAFGKIGFSPRDEAVLRRQLGRPHGLLIVTGPTGSGKTTTLAASIAEMNDTSRKILT
IEDPVEYELPGVSQSQVRSAIGLTFANALRAFLRQDPDVIMVGEIRDGETASIAMQASLTGHLVLSTLHTNSAAAALNRL
TDLGIEPFLVASTLTTVVAQRLARNLCPDCKKPAAVTQQDLEEDPRLTAFGFEIGTILHHAVGCERCAHTGYRGRGALFE
VLEITDEIRRLILNGADEGIIVQTARTQGMQTMLDDGLARCRLGQTTIDEVFRVVAQS
>Mature_538_residues
MKPLMDVDKTSDLALPVSGTDVADGDLTLSIPDEGSDPPRISLAMMQAASSLAGQFSQVFLRESGLFPFRAENGAIWIAA
ADPNRPEPIDALRLTLAGDIAIATAAREDIETILDLVSTRETETEAQAGDSQSPDVTAEDAESLRDLASGAPVVQALEQI
FERAVTWRGTDIHIEPLKRELRVRIRVDGILRLMPVPQNVSARALVSRVKILSGLNIAEHRLPQDGRARMQVRGREFDLR
VATMPTMGGEAAILRLLERNSTLVAFGKIGFSPRDEAVLRRQLGRPHGLLIVTGPTGSGKTTTLAASIAEMNDTSRKILT
IEDPVEYELPGVSQSQVRSAIGLTFANALRAFLRQDPDVIMVGEIRDGETASIAMQASLTGHLVLSTLHTNSAAAALNRL
TDLGIEPFLVASTLTTVVAQRLARNLCPDCKKPAAVTQQDLEEDPRLTAFGFEIGTILHHAVGCERCAHTGYRGRGALFE
VLEITDEIRRLILNGADEGIIVQTARTQGMQTMLDDGLARCRLGQTTIDEVFRVVAQS

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=429, Percent_Identity=43.8228438228438, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1786296, Length=484, Percent_Identity=38.8429752066116, Blast_Score=314, Evalue=9e-87,
Organism=Escherichia coli, GI87082188, Length=242, Percent_Identity=37.1900826446281, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 58151; Mature: 58151

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLMDVDKTSDLALPVSGTDVADGDLTLSIPDEGSDPPRISLAMMQAASSLAGQFSQVF
CCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LRESGLFPFRAENGAIWIAAADPNRPEPIDALRLTLAGDIAIATAAREDIETILDLVSTR
HHHCCCCCEEECCCEEEEEECCCCCCCCHHHHEEEEECCEEEEHHHHHHHHHHHHHHHCC
ETETEAQAGDSQSPDVTAEDAESLRDLASGAPVVQALEQIFERAVTWRGTDIHIEPLKRE
CCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCC
LRVRIRVDGILRLMPVPQNVSARALVSRVKILSGLNIAEHRLPQDGRARMQVRGREFDLR
EEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCEEEEE
VATMPTMGGEAAILRLLERNSTLVAFGKIGFSPRDEAVLRRQLGRPHGLLIVTGPTGSGK
EEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
TTTLAASIAEMNDTSRKILTIEDPVEYELPGVSQSQVRSAIGLTFANALRAFLRQDPDVI
CEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVGEIRDGETASIAMQASLTGHLVLSTLHTNSAAAALNRLTDLGIEPFLVASTLTTVVAQ
EEEECCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RLARNLCPDCKKPAAVTQQDLEEDPRLTAFGFEIGTILHHAVGCERCAHTGYRGRGALFE
HHHHHCCCCCCCCCHHCHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VLEITDEIRRLILNGADEGIIVQTARTQGMQTMLDDGLARCRLGQTTIDEVFRVVAQS
HHHHHHHHHHHHHCCCCCCEEEEECHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKPLMDVDKTSDLALPVSGTDVADGDLTLSIPDEGSDPPRISLAMMQAASSLAGQFSQVF
CCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LRESGLFPFRAENGAIWIAAADPNRPEPIDALRLTLAGDIAIATAAREDIETILDLVSTR
HHHCCCCCEEECCCEEEEEECCCCCCCCHHHHEEEEECCEEEEHHHHHHHHHHHHHHHCC
ETETEAQAGDSQSPDVTAEDAESLRDLASGAPVVQALEQIFERAVTWRGTDIHIEPLKRE
CCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCC
LRVRIRVDGILRLMPVPQNVSARALVSRVKILSGLNIAEHRLPQDGRARMQVRGREFDLR
EEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCEEEEE
VATMPTMGGEAAILRLLERNSTLVAFGKIGFSPRDEAVLRRQLGRPHGLLIVTGPTGSGK
EEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
TTTLAASIAEMNDTSRKILTIEDPVEYELPGVSQSQVRSAIGLTFANALRAFLRQDPDVI
CEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVGEIRDGETASIAMQASLTGHLVLSTLHTNSAAAALNRLTDLGIEPFLVASTLTTVVAQ
EEEECCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RLARNLCPDCKKPAAVTQQDLEEDPRLTAFGFEIGTILHHAVGCERCAHTGYRGRGALFE
HHHHHCCCCCCCCCHHCHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VLEITDEIRRLILNGADEGIIVQTARTQGMQTMLDDGLARCRLGQTTIDEVFRVVAQS
HHHHHHHHHHHHHCCCCCCEEEEECHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]