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The map label for this gene is pilC [H]

Identifier: 182678560

GI number: 182678560

Start: 1785063

End: 1786259

Strand: Reverse

Name: pilC [H]

Synonym: Bind_1585

Alternate gene names: 182678560

Gene position: 1786259-1785063 (Counterclockwise)

Preceding gene: 182678561

Following gene: 182678559

Centisome position: 42.83

GC content: 60.48

Gene sequence:

>1197_bases
GTGACGGTTTATCGTTACAAAGCACTTTCGCTCGATGGCCGATCGATCGAGGAGGAGCGCGAACTCCCCGATCTCGCCGC
CGTCATGCGCGAGCTCGAGCGGCGTAATCTCGTTCTCGTCGCCCATCGTGAAATCCGCCCGAAACGTCAGCTGATTGCCT
TGACCGGCACGGTCAAGCCCGTTGCCGTGACATCTTTCCTCAACGAACTGGCGCTTCTGCTGCGCAGCGGTCTCCCGCTT
GTGGAAGCCCTCGATCTTGGCGCCCATGGCTTGCCGAAACCCCTGGCGCGGGCGGTGACGAGCTTGCGCGGTGCTCTCCT
CGAAGGAAAAAGTTTCTCGCAAGCGTTACGGCAGCGTCCGGAAGTGTTCGGTCCCCTGATCGCCGCTCTCGCCGAGGTGG
CTGAGACGGTCGGCGATCTCGACGGCATGCTCGCGGCGGTCGCCAAGCAGCGCGCCAGCGATCAAGCGCTCTCCGACAAA
GTCTCCGCCGCGCTCCGTTATCCTGCTTTCCTCACGATTTCCGCGTTTCTGGTTCTTCTGTTTTTTCTTTTGCAAGTCAT
CCCGCAATTCGACGGTGTCGTCTCCGAGGGGTCGGGTGATCCCGGCGTCCTCGTGGCGACCGTCTTCGGTCTGTCGCATT
GGCTTGTTGAATGGGAATCTTGGGTGTTGATCGGCTTGCCGTCTCTCGTCTTTGCCGGTTTTCTGATTTCACGCAGCACA
TCAGCCAAGACCTGGCTGGCGAATATTTGCGTGCGTCTGCCGATCATTCGAGGCCTTGCCGATATGCGGCGCTCCGCCGT
CTTTTTCTCGACCCTCGCCATTCTGGTTCGGCAGGGCGTGCCGATGACTGAAAGCTTGCGCGTGATCGAAAATTGTCTCG
GCCCCACGGTCAAACAACGCTTCGCTCTGATCGGCGACGCGGTCCGGCAAGGCAAACGTTTGCATGAGGCGGTCAGTGCC
GTGAATCTTCTCCCGCCAGTCGCCCAGCGCATGCTCCGGATCGGCGAGGAGACAGGTGAACTGGCCAAGGTCGCGACAGA
GGCAGGGGCGCTCTATACGCTGAAACTGGAACAGAGCCTCGTCCGCTTGACCGATATCATTGGTCCCGCTGCCATCCTCT
TCATCGCCGGCATGATCGGCGCCATGATGGCCGCCATCATGTCAACGATCGTGGGCATCGACCAGATGGCCACTTGA

Upstream 100 bases:

>100_bases
AGGTTCAGACAAATCTCAGACAATAAGATGAGATTTCCTTTTCACGCTGTAGAAAAAAATATATCGAAAACCATGGTCTT
TTCGAGAAGGTGAGCGAACG

Downstream 100 bases:

>100_bases
TCGAGGGCCGGTCGATCAACGTCAAGCGATCGACATTATCTTTGCCCAAAAAGTCTTCTCGACCCGCAACAAGGGACCTT
GTCCATGAATGACATTCGTT

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTVYRYKALSLDGRSIEEERELPDLAAVMRELERRNLVLVAHREIRPKRQLIALTGTVKPVAVTSFLNELALLLRSGLPL
VEALDLGAHGLPKPLARAVTSLRGALLEGKSFSQALRQRPEVFGPLIAALAEVAETVGDLDGMLAAVAKQRASDQALSDK
VSAALRYPAFLTISAFLVLLFFLLQVIPQFDGVVSEGSGDPGVLVATVFGLSHWLVEWESWVLIGLPSLVFAGFLISRST
SAKTWLANICVRLPIIRGLADMRRSAVFFSTLAILVRQGVPMTESLRVIENCLGPTVKQRFALIGDAVRQGKRLHEAVSA
VNLLPPVAQRMLRIGEETGELAKVATEAGALYTLKLEQSLVRLTDIIGPAAILFIAGMIGAMMAAIMSTIVGIDQMAT

Sequences:

>Translated_398_residues
MTVYRYKALSLDGRSIEEERELPDLAAVMRELERRNLVLVAHREIRPKRQLIALTGTVKPVAVTSFLNELALLLRSGLPL
VEALDLGAHGLPKPLARAVTSLRGALLEGKSFSQALRQRPEVFGPLIAALAEVAETVGDLDGMLAAVAKQRASDQALSDK
VSAALRYPAFLTISAFLVLLFFLLQVIPQFDGVVSEGSGDPGVLVATVFGLSHWLVEWESWVLIGLPSLVFAGFLISRST
SAKTWLANICVRLPIIRGLADMRRSAVFFSTLAILVRQGVPMTESLRVIENCLGPTVKQRFALIGDAVRQGKRLHEAVSA
VNLLPPVAQRMLRIGEETGELAKVATEAGALYTLKLEQSLVRLTDIIGPAAILFIAGMIGAMMAAIMSTIVGIDQMAT
>Mature_397_residues
TVYRYKALSLDGRSIEEERELPDLAAVMRELERRNLVLVAHREIRPKRQLIALTGTVKPVAVTSFLNELALLLRSGLPLV
EALDLGAHGLPKPLARAVTSLRGALLEGKSFSQALRQRPEVFGPLIAALAEVAETVGDLDGMLAAVAKQRASDQALSDKV
SAALRYPAFLTISAFLVLLFFLLQVIPQFDGVVSEGSGDPGVLVATVFGLSHWLVEWESWVLIGLPSLVFAGFLISRSTS
AKTWLANICVRLPIIRGLADMRRSAVFFSTLAILVRQGVPMTESLRVIENCLGPTVKQRFALIGDAVRQGKRLHEAVSAV
NLLPPVAQRMLRIGEETGELAKVATEAGALYTLKLEQSLVRLTDIIGPAAILFIAGMIGAMMAAIMSTIVGIDQMAT

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=408, Percent_Identity=27.2058823529412, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786295, Length=360, Percent_Identity=27.2222222222222, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42990; Mature: 42859

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYRYKALSLDGRSIEEERELPDLAAVMRELERRNLVLVAHREIRPKRQLIALTGTVKP
CCEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCHHEEEHCCCCCH
VAVTSFLNELALLLRSGLPLVEALDLGAHGLPKPLARAVTSLRGALLEGKSFSQALRQRP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCH
EVFGPLIAALAEVAETVGDLDGMLAAVAKQRASDQALSDKVSAALRYPAFLTISAFLVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
FFLLQVIPQFDGVVSEGSGDPGVLVATVFGLSHWLVEWESWVLIGLPSLVFAGFLISRST
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCC
SAKTWLANICVRLPIIRGLADMRRSAVFFSTLAILVRQGVPMTESLRVIENCLGPTVKQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHH
FALIGDAVRQGKRLHEAVSAVNLLPPVAQRMLRIGEETGELAKVATEAGALYTLKLEQSL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
VRLTDIIGPAAILFIAGMIGAMMAAIMSTIVGIDQMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVYRYKALSLDGRSIEEERELPDLAAVMRELERRNLVLVAHREIRPKRQLIALTGTVKP
CEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCHHEEEHCCCCCH
VAVTSFLNELALLLRSGLPLVEALDLGAHGLPKPLARAVTSLRGALLEGKSFSQALRQRP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCH
EVFGPLIAALAEVAETVGDLDGMLAAVAKQRASDQALSDKVSAALRYPAFLTISAFLVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
FFLLQVIPQFDGVVSEGSGDPGVLVATVFGLSHWLVEWESWVLIGLPSLVFAGFLISRST
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCC
SAKTWLANICVRLPIIRGLADMRRSAVFFSTLAILVRQGVPMTESLRVIENCLGPTVKQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHH
FALIGDAVRQGKRLHEAVSAVNLLPPVAQRMLRIGEETGELAKVATEAGALYTLKLEQSL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
VRLTDIIGPAAILFIAGMIGAMMAAIMSTIVGIDQMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]