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The map label for this gene is syrD [H]

Identifier: 182678507

GI number: 182678507

Start: 1734006

End: 1735670

Strand: Reverse

Name: syrD [H]

Synonym: Bind_1531

Alternate gene names: 182678507

Gene position: 1735670-1734006 (Counterclockwise)

Preceding gene: 182678508

Following gene: 182678505

Centisome position: 41.62

GC content: 54.29

Gene sequence:

>1665_bases
ATGTTCGATAAACGGAACCTCGTTTTCACGGCATTCTCGCTGTTGCGCCCTTTTTGGCTCATCAGCTTGCTCTCGACACT
CATAGGCGCGCTGGGTGGTCTGACCACAGCCTGGTTGCTCGCCACTATCAATCAAGCTCTTTATGCCGATGCTATCGAGT
CCTCGCTAGCGTGGATTTTTGCGGGCCTGGTCGTCCTGAAACTCGTCGGCGAAAGCACCGCCAATCTCAGCAACGGCTTT
GTCGGGCAGCAGATCATCGCGCGCCTGCGCAAGGACCTCTCCGACAAAATCCTGACGGCGCCGATCGATCGCCTCGAACG
CTTTCAGGTTCATCGACTTTCCGCCGCACTAAATCATGATCTCGGACTCATCTCTGCCTTTACCTTTCAAGTTTCGACGC
TGGCGATATCAGCCTCAATAGTGTTTGGCTGCATCGTTTACTTGCTTCTTCTGTCACCCACGCTGTTCCTGATCGCGGCG
GCCGGCATTGGTGCGGGTGCCGCGGCCAACCTTTATGCGCGCCATTTGACTGCCAAGAGGGTGGAACGGATCCGCATGGC
TCATGAAGATCTCCACAAGCATTTTCGCTGCCTTACCCAAGGGGCGAAGGAGTTGCGTCTCAACCGGCTACGCCGCTCCG
CTTTGCGTGAGAACCAGCTTGGGTCGGCAGTCAATCGCATCCGCGATGAGACCTTGTCGTCCACGCGGATCTTCATGGCC
GCGAATACCTTCGCCACCTTGATGTTCTTTGCCGCCATCGGTTTGTTGATCGCTCTCAGGTTCGGCCTCAAGCTCGATAA
ATCCGTATTGTCCGGCTTTATTCTGGTGCTGCTCTTCGTGAAGGGACCGATCGACCAAATTCTCAGTCTTTTGCCCCTCA
TCGGACAAGCGCAAGTCGCATTCAGGAAACTGGTGGAACTCGCGACGGAATTCTCAAATTCCGAACAATATCTACTGCTT
GAACCACAAAAACCTATCTCTCCCATCATCACATCGATCGAACTTTCCGGTGTTCTTTACGCATTTCCAGCCGAGAAGGG
CCCGTCGCCTTTTTCACTTGGCCCGGTCGATCTCACCATCAAGGGCGGCGAGATCTTGTTCATCGTCGGTGAGAACGGCT
CCGGCAAGACGACCTTGATCAAGCTCATTCTTGGCCTTTATACGCCGCAAGAAGGAGCGGTTCTGCTCAATGGCGAGGCC
GTGACGACCGAGACGTGTGACGATTACCGTCAGATCTTCTCGACCGTCTTTTTCGATTATTATCTTTTCGAGGACCTTGC
GACGCCGGACGGTTTTGGATTGGAAAAAGTTACGACTTATCTCGAAAAGCTCGATATTGCGCATAAGGTTAGGATCGAAG
GTGGCGCCTTTTCCACGACCGACCTTTCAGCCGGCCAGCGCAAAAGGCTCGCCTTGATCCATTGCTATCTGGAAAATCGT
CCGGTTCTAGTCTTTGATGAATGGGCCGCCGAACAAGATCCGACCTTCCGGACCATTTTTTATCGGGAATTGCTGCCGGA
CCTCAAACGGCAGGGCAAAACGCTGATCGTCATTTCGCATGATGATCGCTATTTTGACGCGGCCGACCGGCTGATCCGGC
TCAAAGAAGGCCAGATCGTCGAGGCCTGGACCGAGGAAAGTGCCGCTCAGGCTCTCAGAGGGTGA

Upstream 100 bases:

>100_bases
AACGGGAATAACGCCAGATATCCGAGGATCCGGCAATCGACTATTTGCGCCGATGAATATAAATCAGGACATAGGATAAT
CGGCCCGAACGGGGCGTCCC

Downstream 100 bases:

>100_bases
GCTTTGTTTCGCCCACGCCTAATTCGATGAAACATGAAAAGGATCTATGTGGGAATAGGCAAAGCCTGGGCATTCTTGAT
CTGGCCGAGCGCGAAACTGG

Product: cyclic peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MFDKRNLVFTAFSLLRPFWLISLLSTLIGALGGLTTAWLLATINQALYADAIESSLAWIFAGLVVLKLVGESTANLSNGF
VGQQIIARLRKDLSDKILTAPIDRLERFQVHRLSAALNHDLGLISAFTFQVSTLAISASIVFGCIVYLLLLSPTLFLIAA
AGIGAGAAANLYARHLTAKRVERIRMAHEDLHKHFRCLTQGAKELRLNRLRRSALRENQLGSAVNRIRDETLSSTRIFMA
ANTFATLMFFAAIGLLIALRFGLKLDKSVLSGFILVLLFVKGPIDQILSLLPLIGQAQVAFRKLVELATEFSNSEQYLLL
EPQKPISPIITSIELSGVLYAFPAEKGPSPFSLGPVDLTIKGGEILFIVGENGSGKTTLIKLILGLYTPQEGAVLLNGEA
VTTETCDDYRQIFSTVFFDYYLFEDLATPDGFGLEKVTTYLEKLDIAHKVRIEGGAFSTTDLSAGQRKRLALIHCYLENR
PVLVFDEWAAEQDPTFRTIFYRELLPDLKRQGKTLIVISHDDRYFDAADRLIRLKEGQIVEAWTEESAAQALRG

Sequences:

>Translated_554_residues
MFDKRNLVFTAFSLLRPFWLISLLSTLIGALGGLTTAWLLATINQALYADAIESSLAWIFAGLVVLKLVGESTANLSNGF
VGQQIIARLRKDLSDKILTAPIDRLERFQVHRLSAALNHDLGLISAFTFQVSTLAISASIVFGCIVYLLLLSPTLFLIAA
AGIGAGAAANLYARHLTAKRVERIRMAHEDLHKHFRCLTQGAKELRLNRLRRSALRENQLGSAVNRIRDETLSSTRIFMA
ANTFATLMFFAAIGLLIALRFGLKLDKSVLSGFILVLLFVKGPIDQILSLLPLIGQAQVAFRKLVELATEFSNSEQYLLL
EPQKPISPIITSIELSGVLYAFPAEKGPSPFSLGPVDLTIKGGEILFIVGENGSGKTTLIKLILGLYTPQEGAVLLNGEA
VTTETCDDYRQIFSTVFFDYYLFEDLATPDGFGLEKVTTYLEKLDIAHKVRIEGGAFSTTDLSAGQRKRLALIHCYLENR
PVLVFDEWAAEQDPTFRTIFYRELLPDLKRQGKTLIVISHDDRYFDAADRLIRLKEGQIVEAWTEESAAQALRG
>Mature_554_residues
MFDKRNLVFTAFSLLRPFWLISLLSTLIGALGGLTTAWLLATINQALYADAIESSLAWIFAGLVVLKLVGESTANLSNGF
VGQQIIARLRKDLSDKILTAPIDRLERFQVHRLSAALNHDLGLISAFTFQVSTLAISASIVFGCIVYLLLLSPTLFLIAA
AGIGAGAAANLYARHLTAKRVERIRMAHEDLHKHFRCLTQGAKELRLNRLRRSALRENQLGSAVNRIRDETLSSTRIFMA
ANTFATLMFFAAIGLLIALRFGLKLDKSVLSGFILVLLFVKGPIDQILSLLPLIGQAQVAFRKLVELATEFSNSEQYLLL
EPQKPISPIITSIELSGVLYAFPAEKGPSPFSLGPVDLTIKGGEILFIVGENGSGKTTLIKLILGLYTPQEGAVLLNGEA
VTTETCDDYRQIFSTVFFDYYLFEDLATPDGFGLEKVTTYLEKLDIAHKVRIEGGAFSTTDLSAGQRKRLALIHCYLENR
PVLVFDEWAAEQDPTFRTIFYRELLPDLKRQGKTLIVISHDDRYFDAADRLIRLKEGQIVEAWTEESAAQALRG

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=343, Percent_Identity=24.7813411078717, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI255708477, Length=235, Percent_Identity=26.3829787234043, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI9961252, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI4505771, Length=236, Percent_Identity=26.6949152542373, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI9961250, Length=236, Percent_Identity=26.6949152542373, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI9665248, Length=301, Percent_Identity=25.2491694352159, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI171184400, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI148612844, Length=232, Percent_Identity=24.5689655172414, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788540, Length=472, Percent_Identity=34.5338983050847, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1786654, Length=488, Percent_Identity=22.9508196721311, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=31.1320754716981, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786253, Length=196, Percent_Identity=31.1224489795918, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787143, Length=243, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=221, Percent_Identity=30.316742081448, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787112, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787370, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=31.1320754716981, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787105, Length=220, Percent_Identity=25.9090909090909, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994943, Length=202, Percent_Identity=28.2178217821782, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=211, Percent_Identity=26.0663507109005, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790467, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786563, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789672, Length=210, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788225, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786698, Length=210, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788761, Length=232, Percent_Identity=28.0172413793103, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786872, Length=185, Percent_Identity=27.5675675675676, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=28.5, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787164, Length=190, Percent_Identity=29.4736842105263, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=225, Percent_Identity=32, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193202349, Length=238, Percent_Identity=25.6302521008403, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115535101, Length=238, Percent_Identity=24.3697478991597, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=241, Percent_Identity=24.4813278008299, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=228, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=228, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=228, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=228, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996550, Length=223, Percent_Identity=27.3542600896861, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=290, Percent_Identity=24.1379310344828, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=225, Percent_Identity=25.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=221, Percent_Identity=24.8868778280543, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=572, Percent_Identity=21.6783216783217, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=291, Percent_Identity=26.1168384879725, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=251, Percent_Identity=27.4900398406374, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322640, Length=235, Percent_Identity=24.6808510638298, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363262, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653245, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24659289, Length=599, Percent_Identity=22.7045075125209, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI85726357, Length=243, Percent_Identity=24.6913580246914, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666092, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 61315; Mature: 61315

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKRNLVFTAFSLLRPFWLISLLSTLIGALGGLTTAWLLATINQALYADAIESSLAWIF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLVVLKLVGESTANLSNGFVGQQIIARLRKDLSDKILTAPIDRLERFQVHRLSAALNHD
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGLISAFTFQVSTLAISASIVFGCIVYLLLLSPTLFLIAAAGIGAGAAANLYARHLTAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VERIRMAHEDLHKHFRCLTQGAKELRLNRLRRSALRENQLGSAVNRIRDETLSSTRIFMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
ANTFATLMFFAAIGLLIALRFGLKLDKSVLSGFILVLLFVKGPIDQILSLLPLIGQAQVA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
FRKLVELATEFSNSEQYLLLEPQKPISPIITSIELSGVLYAFPAEKGPSPFSLGPVDLTI
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEE
KGGEILFIVGENGSGKTTLIKLILGLYTPQEGAVLLNGEAVTTETCDDYRQIFSTVFFDY
ECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHHHHH
YLFEDLATPDGFGLEKVTTYLEKLDIAHKVRIEGGAFSTTDLSAGQRKRLALIHCYLENR
HHHHHHCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCHHCEEEEEEEECCC
PVLVFDEWAAEQDPTFRTIFYRELLPDLKRQGKTLIVISHDDRYFDAADRLIRLKEGQIV
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEE
EAWTEESAAQALRG
EHHHHHHHHHHHCC
>Mature Secondary Structure
MFDKRNLVFTAFSLLRPFWLISLLSTLIGALGGLTTAWLLATINQALYADAIESSLAWIF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLVVLKLVGESTANLSNGFVGQQIIARLRKDLSDKILTAPIDRLERFQVHRLSAALNHD
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGLISAFTFQVSTLAISASIVFGCIVYLLLLSPTLFLIAAAGIGAGAAANLYARHLTAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VERIRMAHEDLHKHFRCLTQGAKELRLNRLRRSALRENQLGSAVNRIRDETLSSTRIFMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
ANTFATLMFFAAIGLLIALRFGLKLDKSVLSGFILVLLFVKGPIDQILSLLPLIGQAQVA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
FRKLVELATEFSNSEQYLLLEPQKPISPIITSIELSGVLYAFPAEKGPSPFSLGPVDLTI
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEE
KGGEILFIVGENGSGKTTLIKLILGLYTPQEGAVLLNGEAVTTETCDDYRQIFSTVFFDY
ECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHHHHH
YLFEDLATPDGFGLEKVTTYLEKLDIAHKVRIEGGAFSTTDLSAGQRKRLALIHCYLENR
HHHHHHCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCHHCEEEEEEEECCC
PVLVFDEWAAEQDPTFRTIFYRELLPDLKRQGKTLIVISHDDRYFDAADRLIRLKEGQIV
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEE
EAWTEESAAQALRG
EHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]