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The map label for this gene is hfq

Identifier: 182678501

GI number: 182678501

Start: 1727075

End: 1727329

Strand: Direct

Name: hfq

Synonym: Bind_1525

Alternate gene names: 182678501

Gene position: 1727075-1727329 (Clockwise)

Preceding gene: 182678500

Following gene: 182678502

Centisome position: 41.42

GC content: 50.98

Gene sequence:

>255_bases
ATGGCTGTTGATCGCCCGCAGAACCTGCAAGACACTTTTCTCAATTTTGTCCGTAAAAACAAGGTTCCACTTACGATCTT
TCTCGTCAATGGTGTGAAGCTTCAGGGAGTGGTGACCTGGTTCGATAATTTTTGTGTGCTCCTCCGTCGCGATGGACACT
CGCAACTCGTCTACAAGCACGCCATATCTACGATCATGCCGGGAGCACCTATTCAGATGTTCGAACCCGGCGATGAAGCC
GGACATGCCGGCTAG

Upstream 100 bases:

>100_bases
GCGACTTTGGCTTTCGGCCGTTCTAATGGCGCCGTTTATTTTGCCCAAGGACGTTTTTTGTTCCACCAATATGTCACGAC
AACAAGAACAGGACTCGATA

Downstream 100 bases:

>100_bases
AGCATAACCCCGAAAGTCGGAAGCTTTTGGGAGAATCGGCTTCTACCGGTTTATTTTTGCGGACACAGGAGTTTCCCATA
GACGCACCGACCGTTTCACC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 83

Protein sequence:

>84_residues
MAVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGAPIQMFEPGDEA
GHAG

Sequences:

>Translated_84_residues
MAVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGAPIQMFEPGDEA
GHAG
>Mature_83_residues
AVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGAPIQMFEPGDEAG
HAG

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=82, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_BEII9 (B2IB74)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832647.1
- GeneID:   6200304
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1525
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- ProtClustDB:   CLSK2405506
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9410; Mature: 9279

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKH
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHEEECCCEEEEEEECCCCHHHHHH
AISTIMPGAPIQMFEPGDEAGHAG
HHHHHCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
AVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKH
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHEEECCCEEEEEEECCCCHHHHHH
AISTIMPGAPIQMFEPGDEAGHAG
HHHHHCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA