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The map label for this gene is yjcE [H]

Identifier: 182678213

GI number: 182678213

Start: 1425234

End: 1426874

Strand: Direct

Name: yjcE [H]

Synonym: Bind_1228

Alternate gene names: 182678213

Gene position: 1425234-1426874 (Clockwise)

Preceding gene: 182678212

Following gene: 182678219

Centisome position: 34.18

GC content: 59.41

Gene sequence:

>1641_bases
GTGGAAACGGTTGTCAGTATCCTGATTTTTCTTGTGGCTGTTGTGGTCAGCGGCTCGCTCTCGCGCCTGTTACCCCTTCC
AGTTCCGCTGCCCCTCGTGCAGATCGCGCTTGGCGCTTTGATCACGGATGTGACCAGCCTTGGTGTCACTCTCGATCCAG
AAATTTTCTTTTTGCTGTTCCTGCCGCCGCTATTGTTCCTGGATGGCTGGCGCATTCCCAAGGAAGGCCTGTTCCGCGAC
AAGGGCACAATTCTCGAACTGGCCCTGGGGCTCGTCGTCTTCACGGTGGTCCTTGTCGGTTTCTTCGTCAATTGGATGAT
CCCGGCCATGCCGCTGGCCGTTGCTTTCGCGCTTGCCGCCATCGTCTCGCCGACAGATCCGATTGCCGTCTCGGCTCTCG
CCTCCAGGGTGCCGATCCCCAATCGCATGATGCATATTCTCGAAGGCGAATCCCTGCTCAATGACGCCTCGGGCCTCGTT
TGCATGCGTTTTGCCGTGGCGGCGGCGCTGACCGGCCAATTCTCGCTGACCCAGGCTTTTGGCACTTTTCTCTGGCTGGC
GATTGGCGGTATCGCGATCGGGGTCGGCGTGACCTGGATCGTCACCAAGGTGAAATATTGGATAGCGCGTCTGGTTGGCG
AGGATACCGGGGCACAAATCCTGATCAGCCTCTTGATCCCCTTTGGCGCCTATCTGCTCGCTGAACATTTCCATTGTTCC
GGCATTCTGGCGGCCGTCGCCGCCGGCATCACCATGAGCTATGTCGAGCAGTCCGGGCACATTCTCGCCATTACCCGCGT
CCGCCGCAGCACGGTTTGGGATACGGTGCAATTTACCGCCAATGGCATTATTTTCGTTTTGCTTGGCGAGCAATTGCCGG
AAATCGTCAATGGCGCCACGCGGGTCGTGCGTGAGACGGGCCATCACGATCCGATCTGGCTGCTGGTCTATATTTTGGCG
ATCAATCTCGCCTTGGGGGTCTTGCGTTTCGCCTGGGTCTGGTTGTCCCTGCGTTTCACTTTGTTTCGGGCTTCCCGCCA
GGGTTATCCCGTCAAGATCCAAACCATGCGTGTGGTGTCCTGCGTCTCGTTAGCCGGTGTACGCGGGACGATTACACTTG
CTGGTGTTCTGACCCTGCCGTTATCGATGCCGGACTGGTCACCCTTTCCGGCGCGCGATCTTGCCATCTGCCTGGCCGCC
GGCGTGATTGTCATTTCCCTGATCGTGGCGGGTGTGGGTCTGCCGCCACTGCTCAAGGGGCTGGAACTGCCGCCCGAAAC
GTCGCATCGAGAAGAAGAAGATCACGCCCGTATTGCCGCCGCGGAGGCCGCGATCAGGGCGATCGAGCGCGGGCAACATG
ATTTGAGCCAGGGCCGTACCGACGCGGATCTTTATACGAGCGCGGGCTCCCGCATCATGGCCTTGTATCGTCAGCGTATC
GAGGGGCGTTCCAAGAAGGGTGCGGAAGCCGATCTCGTCAAAAAGACCGAGGAGGTCGAACGCCAGCTCCGCCTCGCGGG
CCTGCGGGCTGAGCGAGACGAGCTCTATCGTATCGCGCGTGCACGCAAACTATCAGATGAAACCGTCCGCAGATTGGTGC
GGGAAATCGACTTGCAGGAAACGCGTTTCAGCGCGTCATGA

Upstream 100 bases:

>100_bases
GTCGATCTCATGGCTCGCTATGCCGCCCGCCTGACCGAAACATCGTAAATTTTTTAAGAAAATGGCGTTAAAGCGGGAGG
GATAAGAAGAGAGGCGGCGC

Downstream 100 bases:

>100_bases
CCGGCTTCGTTGCGGAATGGCCGCGCTTGTCAGGAGTAGACAGCCGCGACCTTGATCTGTCCCTCGTTGTTCAAGACCTG
GAGCGACACATCATTGTCGT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
METVVSILIFLVAVVVSGSLSRLLPLPVPLPLVQIALGALITDVTSLGVTLDPEIFFLLFLPPLLFLDGWRIPKEGLFRD
KGTILELALGLVVFTVVLVGFFVNWMIPAMPLAVAFALAAIVSPTDPIAVSALASRVPIPNRMMHILEGESLLNDASGLV
CMRFAVAAALTGQFSLTQAFGTFLWLAIGGIAIGVGVTWIVTKVKYWIARLVGEDTGAQILISLLIPFGAYLLAEHFHCS
GILAAVAAGITMSYVEQSGHILAITRVRRSTVWDTVQFTANGIIFVLLGEQLPEIVNGATRVVRETGHHDPIWLLVYILA
INLALGVLRFAWVWLSLRFTLFRASRQGYPVKIQTMRVVSCVSLAGVRGTITLAGVLTLPLSMPDWSPFPARDLAICLAA
GVIVISLIVAGVGLPPLLKGLELPPETSHREEEDHARIAAAEAAIRAIERGQHDLSQGRTDADLYTSAGSRIMALYRQRI
EGRSKKGAEADLVKKTEEVERQLRLAGLRAERDELYRIARARKLSDETVRRLVREIDLQETRFSAS

Sequences:

>Translated_546_residues
METVVSILIFLVAVVVSGSLSRLLPLPVPLPLVQIALGALITDVTSLGVTLDPEIFFLLFLPPLLFLDGWRIPKEGLFRD
KGTILELALGLVVFTVVLVGFFVNWMIPAMPLAVAFALAAIVSPTDPIAVSALASRVPIPNRMMHILEGESLLNDASGLV
CMRFAVAAALTGQFSLTQAFGTFLWLAIGGIAIGVGVTWIVTKVKYWIARLVGEDTGAQILISLLIPFGAYLLAEHFHCS
GILAAVAAGITMSYVEQSGHILAITRVRRSTVWDTVQFTANGIIFVLLGEQLPEIVNGATRVVRETGHHDPIWLLVYILA
INLALGVLRFAWVWLSLRFTLFRASRQGYPVKIQTMRVVSCVSLAGVRGTITLAGVLTLPLSMPDWSPFPARDLAICLAA
GVIVISLIVAGVGLPPLLKGLELPPETSHREEEDHARIAAAEAAIRAIERGQHDLSQGRTDADLYTSAGSRIMALYRQRI
EGRSKKGAEADLVKKTEEVERQLRLAGLRAERDELYRIARARKLSDETVRRLVREIDLQETRFSAS
>Mature_546_residues
METVVSILIFLVAVVVSGSLSRLLPLPVPLPLVQIALGALITDVTSLGVTLDPEIFFLLFLPPLLFLDGWRIPKEGLFRD
KGTILELALGLVVFTVVLVGFFVNWMIPAMPLAVAFALAAIVSPTDPIAVSALASRVPIPNRMMHILEGESLLNDASGLV
CMRFAVAAALTGQFSLTQAFGTFLWLAIGGIAIGVGVTWIVTKVKYWIARLVGEDTGAQILISLLIPFGAYLLAEHFHCS
GILAAVAAGITMSYVEQSGHILAITRVRRSTVWDTVQFTANGIIFVLLGEQLPEIVNGATRVVRETGHHDPIWLLVYILA
INLALGVLRFAWVWLSLRFTLFRASRQGYPVKIQTMRVVSCVSLAGVRGTITLAGVLTLPLSMPDWSPFPARDLAICLAA
GVIVISLIVAGVGLPPLLKGLELPPETSHREEEDHARIAAAEAAIRAIERGQHDLSQGRTDADLYTSAGSRIMALYRQRI
EGRSKKGAEADLVKKTEEVERQLRLAGLRAERDELYRIARARKLSDETVRRLVREIDLQETRFSAS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=464, Percent_Identity=24.3534482758621, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI5454070, Length=445, Percent_Identity=26.2921348314607, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI27734935, Length=430, Percent_Identity=24.8837209302326, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI294997330, Length=423, Percent_Identity=26.4775413711584, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI110227626, Length=423, Percent_Identity=26.4775413711584, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI15529998, Length=441, Percent_Identity=23.3560090702948, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI41872703, Length=468, Percent_Identity=23.5042735042735, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI14211919, Length=412, Percent_Identity=25.2427184466019, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI27777632, Length=561, Percent_Identity=25.3119429590018, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI194239733, Length=422, Percent_Identity=27.2511848341232, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4759144, Length=398, Percent_Identity=25.6281407035176, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1790501, Length=546, Percent_Identity=41.7582417582418, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25150332, Length=422, Percent_Identity=23.9336492890995, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71999817, Length=558, Percent_Identity=23.1182795698925, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71999819, Length=558, Percent_Identity=23.1182795698925, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71999821, Length=558, Percent_Identity=23.1182795698925, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987535, Length=436, Percent_Identity=25.4587155963303, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71987537, Length=436, Percent_Identity=25.4587155963303, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71980847, Length=478, Percent_Identity=22.3849372384937, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25147678, Length=518, Percent_Identity=23.3590733590734, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993590, Length=282, Percent_Identity=28.0141843971631, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71993582, Length=282, Percent_Identity=28.0141843971631, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990932, Length=404, Percent_Identity=22.029702970297, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71990924, Length=432, Percent_Identity=21.5277777777778, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71987559, Length=398, Percent_Identity=23.3668341708543, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71987545, Length=398, Percent_Identity=23.3668341708543, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=279, Percent_Identity=25.089605734767, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221473215, Length=447, Percent_Identity=23.489932885906, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281364513, Length=442, Percent_Identity=23.9819004524887, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221473222, Length=442, Percent_Identity=23.9819004524887, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221473212, Length=459, Percent_Identity=23.0936819172113, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221510738, Length=415, Percent_Identity=26.5060240963855, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221510734, Length=415, Percent_Identity=26.5060240963855, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI221510732, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221510736, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221510740, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24585580, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24585578, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360447, Length=407, Percent_Identity=24.5700245700246, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 59463; Mature: 59463

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCC
>Mature Secondary Structure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HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]