Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 182678123

GI number: 182678123

Start: 1319396

End: 1319992

Strand: Direct

Name: pabA [H]

Synonym: Bind_1138

Alternate gene names: 182678123

Gene position: 1319396-1319992 (Clockwise)

Preceding gene: 182678122

Following gene: 182678124

Centisome position: 31.64

GC content: 57.96

Gene sequence:

>597_bases
ATGATCCTCATCATCGACAATTACGATTCCTTCGTCTTCAATATTGCGCGCTATTTCGAAAATCTTGGCGCGGCGATACG
CGTTGAGCGCAACGACTCTCTGGATCTTGCTGAAATCGAGAAGCTTGCACCAAAAGCCATCGTTTTGTCGCCTGGCCCCT
GTGGCCCGGCCGAGGCGGGAGTGTCGCTTCAGGTCTTGACGCGCCTTGCCGGTCGCATGCCGATCCTCGGCATTTGCCTT
GGCCATCAATGTCTCGGCATGGCCTTCGGCGGTCAGATCACCCGGGCACGCGAACCGATCCATGGGCGAATCCTGCGCCT
TGCGCATGGCGGGCAGGGTCTCTTCGTCGGCCTTCCCTCGCCGATCGAGGCCGGCTGCTACCATTCTTTGATCGTCGAGG
CGACGCCAGCCATGGACGCGGCCCTGCACGTTGATGCTTGGTCCGAGGCGGGAGAAATTCTCGCGCTCTCCCACCGTATC
TGGCCGCTGTTTGGCGTCCAGTTTCATCCAGAATCCGTCCTGACTCCTTGGGGAGACACAATTTTTCGCAATTTTTTAAA
TGTGGTTGAGGCTTGGCATGCCCCTGTTTTGGAGTGA

Upstream 100 bases:

>100_bases
TCAACGCGGGCGGCGGTATCACGCTCCTTTCCGATCCAGAAGCCGAATATGCCGAAAGCCTCGCCAAGCTTGAACGGATT
TTCGAGCGGGAGGGTTCGGC

Downstream 100 bases:

>100_bases
TGGCGCACTTTTCGAAACGGCGGTCCATCCCTACGATCTAACCGATCGCGGCTTGCTGCTCGGTGACGGCCTGTTTGACA
CCGCTCTGGTCCTGCGGGGA

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MILIIDNYDSFVFNIARYFENLGAAIRVERNDSLDLAEIEKLAPKAIVLSPGPCGPAEAGVSLQVLTRLAGRMPILGICL
GHQCLGMAFGGQITRAREPIHGRILRLAHGGQGLFVGLPSPIEAGCYHSLIVEATPAMDAALHVDAWSEAGEILALSHRI
WPLFGVQFHPESVLTPWGDTIFRNFLNVVEAWHAPVLE

Sequences:

>Translated_198_residues
MILIIDNYDSFVFNIARYFENLGAAIRVERNDSLDLAEIEKLAPKAIVLSPGPCGPAEAGVSLQVLTRLAGRMPILGICL
GHQCLGMAFGGQITRAREPIHGRILRLAHGGQGLFVGLPSPIEAGCYHSLIVEATPAMDAALHVDAWSEAGEILALSHRI
WPLFGVQFHPESVLTPWGDTIFRNFLNVVEAWHAPVLE
>Mature_198_residues
MILIIDNYDSFVFNIARYFENLGAAIRVERNDSLDLAEIEKLAPKAIVLSPGPCGPAEAGVSLQVLTRLAGRMPILGICL
GHQCLGMAFGGQITRAREPIHGRILRLAHGGQGLFVGLPSPIEAGCYHSLIVEATPAMDAALHVDAWSEAGEILALSHRI
WPLFGVQFHPESVLTPWGDTIFRNFLNVVEAWHAPVLE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=52.4064171122995, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1787517, Length=200, Percent_Identity=39.5, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=38.8297872340425, Blast_Score=152, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=31.7535545023697, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21523; Mature: 21523

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIIDNYDSFVFNIARYFENLGAAIRVERNDSLDLAEIEKLAPKAIVLSPGPCGPAEAG
CEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCHHCC
VSLQVLTRLAGRMPILGICLGHQCLGMAFGGQITRAREPIHGRILRLAHGGQGLFVGLPS
CHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHCCCCHHHEEEEEEECCCEEEEECCC
PIEAGCYHSLIVEATPAMDAALHVDAWSEAGEILALSHRIWPLFGVQFHPESVLTPWGDT
CCCCCCHHHHEEECCCCCCCEEEECCCCCCCCEEEEECCCCEEECEEECCCCCCCCCHHH
IFRNFLNVVEAWHAPVLE
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MILIIDNYDSFVFNIARYFENLGAAIRVERNDSLDLAEIEKLAPKAIVLSPGPCGPAEAG
CEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCHHCC
VSLQVLTRLAGRMPILGICLGHQCLGMAFGGQITRAREPIHGRILRLAHGGQGLFVGLPS
CHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHCCCCHHHEEEEEEECCCEEEEECCC
PIEAGCYHSLIVEATPAMDAALHVDAWSEAGEILALSHRIWPLFGVQFHPESVLTPWGDT
CCCCCCHHHHEEECCCCCCCEEEECCCCCCCCEEEEECCCCEEECEEECCCCCCCCCHHH
IFRNFLNVVEAWHAPVLE
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]