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The map label for this gene is pabB [H]

Identifier: 182678122

GI number: 182678122

Start: 1317969

End: 1319399

Strand: Direct

Name: pabB [H]

Synonym: Bind_1137

Alternate gene names: 182678122

Gene position: 1317969-1319399 (Clockwise)

Preceding gene: 182678116

Following gene: 182678123

Centisome position: 31.6

GC content: 58.84

Gene sequence:

>1431_bases
TTGTCTTCACTCGACCCTTTGATCCTGCATGTCGCGCCTCTCGATTCGATCGCGCCCCTCGAAGCGGCGGAACGGCTTGT
CGGCCTGCCGGGATTGGCGTTTCTCGACAGCGCCCTCCCCATGCCGCGGCTCGGACGTTATTCCTATCTCGCTGCCGATC
CGTTTGGCTGGCTGACCGTAGAAAATGGGATCGCCTTTTGGAATGGCCAACCTTGCCCTGAGCCGCCGCTTGCGGCGCTG
CGTGCCCGGCTCGCAGCCCATGCACTGCCCAAAGACGAGCGTTTGCTACCTCTCCAGACCGGTGTGATCGGTTATTTCGC
CTATGATTTCGCTCCTTGCCTTGATCCGGCGGCTAAGGTCGTCCGTTCTCAAGGGGTTCAGGCGAGCCTGGGTTTCTATG
ATGTCGTGCTCGCCTTCGATCACGAGACGGGCAAGGGCTGGCTGATGGCCTCGGGCCTGCCGGAAACGGAACCCGAGGCG
CGCCATCGACGCGCGGAGCAGCGTCTTGCTCAGTTCAAGAGCCTGCTTGAGCGCCCACTTGAAAATCCCATGCAGGGAGC
CTCACATCGTGATTCTCCTGTGCCGACCTCCTTGGCTTGGCGCCAGCATTGGCGAAAGGCGGACTATCTCTCCGCTGTGC
GGCGGGTCAAGGAGCATATTCTGGCGGGTGATCTCTATCAGGCGAATATAGCACAATGTTTCGAGGCTGATGTGCCACGT
GGCTTCGATTCCTGGCGATTCTATAAGGACTTGCGTTCACGCAATCCCGCGCCTTATGCCGCCTTTCTCGCGCAGGAGGG
CCGGCACACGGGCGATGCCATTGCCTCGAGTTCGCCCGAGGCTTTTCTCTCCCTTATCGACGGCATGGTGGAAACGCGCC
CGATCAAGGGGACCCAAAAACGCCTTGAAGAGCCGGAGCTCGACGCTGCTTGTCGCGATAATTTGGCTCGATCCGAGAAG
GATCGAGCCGAAAATATTATGATCGTCGATCTCTTGCGCAATGATCTTTCGAAAGTTTGCACGGCCGCTTCAATCGAAGT
GCCGGACCTGTGCGTCGTTGAAACTTATGCGGGCGTGCATCACCTCGTTTCATCGGTGACAGGCCGTTTACGGCCAGGGT
GCGACGCGCTCGATCTGTTTGCCGCCTGTTTTCCGGGCGGCTCGATTACCGGTGCTCCGAAGCTCAAGGCGATGGAAATT
ATCGCCGCGATCGAAAACAGGGCGCGAGGACCTTATTGCGGCGCCATTGGCTTTATCGCCTTCAATGGCGATATGGCGCT
CAATATTGCGATCCGAACAATCGTCTTTGCTGGCGATAAGGCCTGTCTCAACGCGGGCGGCGGTATCACGCTCCTTTCCG
ATCCAGAAGCCGAATATGCCGAAAGCCTCGCCAAGCTTGAACGGATTTTCGAGCGGGAGGGTTCGGCATGA

Upstream 100 bases:

>100_bases
TATGGGAAGGGATTAGAACAGGTTTGTTGCGTGTTGAACCGCTGTCAGGCAATTTGACGCGCAAATTCATCGGCCATAAT
GGCGAAACGGCGCCGATCCC

Downstream 100 bases:

>100_bases
TCCTCATCATCGACAATTACGATTCCTTCGTCTTCAATATTGCGCGCTATTTCGAAAATCTTGGCGCGGCGATACGCGTT
GAGCGCAACGACTCTCTGGA

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSSLDPLILHVAPLDSIAPLEAAERLVGLPGLAFLDSALPMPRLGRYSYLAADPFGWLTVENGIAFWNGQPCPEPPLAAL
RARLAAHALPKDERLLPLQTGVIGYFAYDFAPCLDPAAKVVRSQGVQASLGFYDVVLAFDHETGKGWLMASGLPETEPEA
RHRRAEQRLAQFKSLLERPLENPMQGASHRDSPVPTSLAWRQHWRKADYLSAVRRVKEHILAGDLYQANIAQCFEADVPR
GFDSWRFYKDLRSRNPAPYAAFLAQEGRHTGDAIASSSPEAFLSLIDGMVETRPIKGTQKRLEEPELDAACRDNLARSEK
DRAENIMIVDLLRNDLSKVCTAASIEVPDLCVVETYAGVHHLVSSVTGRLRPGCDALDLFAACFPGGSITGAPKLKAMEI
IAAIENRARGPYCGAIGFIAFNGDMALNIAIRTIVFAGDKACLNAGGGITLLSDPEAEYAESLAKLERIFEREGSA

Sequences:

>Translated_476_residues
MSSLDPLILHVAPLDSIAPLEAAERLVGLPGLAFLDSALPMPRLGRYSYLAADPFGWLTVENGIAFWNGQPCPEPPLAAL
RARLAAHALPKDERLLPLQTGVIGYFAYDFAPCLDPAAKVVRSQGVQASLGFYDVVLAFDHETGKGWLMASGLPETEPEA
RHRRAEQRLAQFKSLLERPLENPMQGASHRDSPVPTSLAWRQHWRKADYLSAVRRVKEHILAGDLYQANIAQCFEADVPR
GFDSWRFYKDLRSRNPAPYAAFLAQEGRHTGDAIASSSPEAFLSLIDGMVETRPIKGTQKRLEEPELDAACRDNLARSEK
DRAENIMIVDLLRNDLSKVCTAASIEVPDLCVVETYAGVHHLVSSVTGRLRPGCDALDLFAACFPGGSITGAPKLKAMEI
IAAIENRARGPYCGAIGFIAFNGDMALNIAIRTIVFAGDKACLNAGGGITLLSDPEAEYAESLAKLERIFEREGSA
>Mature_475_residues
SSLDPLILHVAPLDSIAPLEAAERLVGLPGLAFLDSALPMPRLGRYSYLAADPFGWLTVENGIAFWNGQPCPEPPLAALR
ARLAAHALPKDERLLPLQTGVIGYFAYDFAPCLDPAAKVVRSQGVQASLGFYDVVLAFDHETGKGWLMASGLPETEPEAR
HRRAEQRLAQFKSLLERPLENPMQGASHRDSPVPTSLAWRQHWRKADYLSAVRRVKEHILAGDLYQANIAQCFEADVPRG
FDSWRFYKDLRSRNPAPYAAFLAQEGRHTGDAIASSSPEAFLSLIDGMVETRPIKGTQKRLEEPELDAACRDNLARSEKD
RAENIMIVDLLRNDLSKVCTAASIEVPDLCVVETYAGVHHLVSSVTGRLRPGCDALDLFAACFPGGSITGAPKLKAMEII
AAIENRARGPYCGAIGFIAFNGDMALNIAIRTIVFAGDKACLNAGGGITLLSDPEAEYAESLAKLERIFEREGSA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=455, Percent_Identity=35.8241758241758, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1787518, Length=392, Percent_Identity=30.3571428571429, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786809, Length=277, Percent_Identity=23.1046931407942, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=478, Percent_Identity=32.6359832635983, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=427, Percent_Identity=26.6978922716628, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51846; Mature: 51715

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLDPLILHVAPLDSIAPLEAAERLVGLPGLAFLDSALPMPRLGRYSYLAADPFGWLTV
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCCEEEE
ENGIAFWNGQPCPEPPLAALRARLAAHALPKDERLLPLQTGVIGYFAYDFAPCLDPAAKV
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
VRSQGVQASLGFYDVVLAFDHETGKGWLMASGLPETEPEARHRRAEQRLAQFKSLLERPL
HHHCCCEEECCCEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ENPMQGASHRDSPVPTSLAWRQHWRKADYLSAVRRVKEHILAGDLYQANIAQCFEADVPR
CCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GFDSWRFYKDLRSRNPAPYAAFLAQEGRHTGDAIASSSPEAFLSLIDGMVETRPIKGTQK
CCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RLEEPELDAACRDNLARSEKDRAENIMIVDLLRNDLSKVCTAASIEVPDLCVVETYAGVH
HCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
HLVSSVTGRLRPGCDALDLFAACFPGGSITGAPKLKAMEIIAAIENRARGPYCGAIGFIA
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
FNGDMALNIAIRTIVFAGDKACLNAGGGITLLSDPEAEYAESLAKLERIFEREGSA
ECCCEEEEEEEEEEEEECCHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSLDPLILHVAPLDSIAPLEAAERLVGLPGLAFLDSALPMPRLGRYSYLAADPFGWLTV
CCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCCEEEE
ENGIAFWNGQPCPEPPLAALRARLAAHALPKDERLLPLQTGVIGYFAYDFAPCLDPAAKV
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
VRSQGVQASLGFYDVVLAFDHETGKGWLMASGLPETEPEARHRRAEQRLAQFKSLLERPL
HHHCCCEEECCCEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ENPMQGASHRDSPVPTSLAWRQHWRKADYLSAVRRVKEHILAGDLYQANIAQCFEADVPR
CCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GFDSWRFYKDLRSRNPAPYAAFLAQEGRHTGDAIASSSPEAFLSLIDGMVETRPIKGTQK
CCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RLEEPELDAACRDNLARSEKDRAENIMIVDLLRNDLSKVCTAASIEVPDLCVVETYAGVH
HCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
HLVSSVTGRLRPGCDALDLFAACFPGGSITGAPKLKAMEIIAAIENRARGPYCGAIGFIA
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
FNGDMALNIAIRTIVFAGDKACLNAGGGITLLSDPEAEYAESLAKLERIFEREGSA
ECCCEEEEEEEEEEEEECCHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]