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The map label for this gene is gpt [H]

Identifier: 182678116

GI number: 182678116

Start: 1309502

End: 1309981

Strand: Direct

Name: gpt [H]

Synonym: Bind_1131

Alternate gene names: 182678116

Gene position: 1309502-1309981 (Clockwise)

Preceding gene: 182678115

Following gene: 182678122

Centisome position: 31.4

GC content: 56.88

Gene sequence:

>480_bases
ATGAGTCAGAAAAATTATCAAGTGTCCTGGGATCAGTTCCATCGCGACGCCAGGACGCTCGCCCGGCGTTTGATGGATCT
TGGACCTTTCCGTGGCATGGCCGCCGTGACGCGCGGCGGTCTTGTGCCGGCGGCGATCGTCGCGCGTGAACTTAATCTGC
GCCTGATTGATACATTTTGCGTGGCGAGCTATGGCGCCGATAATGATCTCGCGCAGACCAAGATCCTGAAAAGGATCACG
GCTGAACTTGCAGGAGAAGAGGGCCAAGGGCTTCTCGTCATCGACGATCTTGTCGATACCGGCACCACGGCGCGGCTCAT
CAGAGAACAATTGCCGAAGGCGCATATAGCGACACTCTATGCCAAACCGATGGGTCTGCCGCTCGTCGACACGTTTGTCA
TGGAAGTCGCACAGGAAACCTGGATCGATTTTCCGTGGGATCTCGGATTGGATTTTCAGGCGCCCCTGGTGCCGCGGTAA

Upstream 100 bases:

>100_bases
CAGATCGTTGTGCGCGGCAAGGATGCGGAGCTGGTCGGCCAGGTTGTCGAAAAGGTCCGCGCGATGATTACACGCCTTTC
CGCAGGCTGACGCCCACACC

Downstream 100 bases:

>100_bases
TTTTGACACATGCTTCGCCAAGGCTTGATCATGTAGAGAGTAATGGCATTTCCCCTGGCGGCATTTTGTTCTAAGCAGAG
TGCAGTTATTCCGGCTTTGG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSQKNYQVSWDQFHRDARTLARRLMDLGPFRGMAAVTRGGLVPAAIVARELNLRLIDTFCVASYGADNDLAQTKILKRIT
AELAGEEGQGLLVIDDLVDTGTTARLIREQLPKAHIATLYAKPMGLPLVDTFVMEVAQETWIDFPWDLGLDFQAPLVPR

Sequences:

>Translated_159_residues
MSQKNYQVSWDQFHRDARTLARRLMDLGPFRGMAAVTRGGLVPAAIVARELNLRLIDTFCVASYGADNDLAQTKILKRIT
AELAGEEGQGLLVIDDLVDTGTTARLIREQLPKAHIATLYAKPMGLPLVDTFVMEVAQETWIDFPWDLGLDFQAPLVPR
>Mature_158_residues
SQKNYQVSWDQFHRDARTLARRLMDLGPFRGMAAVTRGGLVPAAIVARELNLRLIDTFCVASYGADNDLAQTKILKRITA
ELAGEEGQGLLVIDDLVDTGTTARLIREQLPKAHIATLYAKPMGLPLVDTFVMEVAQETWIDFPWDLGLDFQAPLVPR

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=159, Percent_Identity=51.5723270440252, Blast_Score=159, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17695; Mature: 17563

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKNYQVSWDQFHRDARTLARRLMDLGPFRGMAAVTRGGLVPAAIVARELNLRLIDTFC
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCHHHHHHHH
VASYGADNDLAQTKILKRITAELAGEEGQGLLVIDDLVDTGTTARLIREQLPKAHIATLY
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHH
AKPMGLPLVDTFVMEVAQETWIDFPWDLGLDFQAPLVPR
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQKNYQVSWDQFHRDARTLARRLMDLGPFRGMAAVTRGGLVPAAIVARELNLRLIDTFC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCHHHHHHHH
VASYGADNDLAQTKILKRITAELAGEEGQGLLVIDDLVDTGTTARLIREQLPKAHIATLY
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHH
AKPMGLPLVDTFVMEVAQETWIDFPWDLGLDFQAPLVPR
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA