Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 182678085

GI number: 182678085

Start: 1265907

End: 1266599

Strand: Direct

Name: kdpE [H]

Synonym: Bind_1100

Alternate gene names: 182678085

Gene position: 1265907-1266599 (Clockwise)

Preceding gene: 182678084

Following gene: 182678086

Centisome position: 30.36

GC content: 55.56

Gene sequence:

>693_bases
ATGAATGCGTTTCGGCCCCGGGTTCTTGTTATTGACGATGAGCCGCAGATTCATCGCTTTTTGCGGCCAGCTCTGGATGC
GGCGGGCTATGAGCCGGTCCGTGCCGATAATGCCACTGATGGTCTCAAGGAAATAGCCCGCAAGGTTCCCGATGCGGTCG
TGCTCGATCTTGGTCTGCCCGACATGGACGGCAAGGACGTTTTGCAAAAAGCGCGCGATTTCTATGATGGTCCGATCATC
ATTCTGTCCGCTCGCGATCGCGAGACGGAAAAGATTACCGCTCTCGATATGGGTGCGGATGATTATGTGGAAAAGCCTTT
TGGCATCGGCGAGTTGCTGGCGCGTTTGCGCGTTGCGATGCGCCACAGATTGATCCGGAATGAAGCCTCGCCAGTCGTAC
AAGCCGGAGACGTTTCGGTTGATCTTGTGAACCGGCTTGTCACACGGGGTGGCGAGGTGATCCGCCTTTCTCCCAAGGAA
TATGATCTGCTGGCCAAACTGCTTGAAGCGGGTGGCAAGGTCGTCACCCACAAACAGCTTCTCACGGCGGTGTGGGGACC
GGCCCATGCGGAAGACGTGCAATATCTCCGTGTATTCGTTGGTCAGCTCAGGCAAAAGTTGGAGAACGATCCTGCATCAC
CCAAATTGATCACGACCGAACCGGGCGTGGGCTACCGCTTTTATATCCCTTAA

Upstream 100 bases:

>100_bases
TGGGGGGCCGCATCGCCGCTGCCAGTCCCATCCATGGCGATAAAGGCACCCGTGTTTTGATTAGCCTTCCAAAGATGGCT
GTGATTCCGCAAGGCAGCAC

Downstream 100 bases:

>100_bases
TCATCATACGGTCGCCGAAAGGCACATTCTGTCTCTTTCGTATTTATACAACGCTTATGTTCACCAAAAGAAGACGTATG
GATAATTGATGTCGTCCCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNAFRPRVLVIDDEPQIHRFLRPALDAAGYEPVRADNATDGLKEIARKVPDAVVLDLGLPDMDGKDVLQKARDFYDGPII
ILSARDRETEKITALDMGADDYVEKPFGIGELLARLRVAMRHRLIRNEASPVVQAGDVSVDLVNRLVTRGGEVIRLSPKE
YDLLAKLLEAGGKVVTHKQLLTAVWGPAHAEDVQYLRVFVGQLRQKLENDPASPKLITTEPGVGYRFYIP

Sequences:

>Translated_230_residues
MNAFRPRVLVIDDEPQIHRFLRPALDAAGYEPVRADNATDGLKEIARKVPDAVVLDLGLPDMDGKDVLQKARDFYDGPII
ILSARDRETEKITALDMGADDYVEKPFGIGELLARLRVAMRHRLIRNEASPVVQAGDVSVDLVNRLVTRGGEVIRLSPKE
YDLLAKLLEAGGKVVTHKQLLTAVWGPAHAEDVQYLRVFVGQLRQKLENDPASPKLITTEPGVGYRFYIP
>Mature_230_residues
MNAFRPRVLVIDDEPQIHRFLRPALDAAGYEPVRADNATDGLKEIARKVPDAVVLDLGLPDMDGKDVLQKARDFYDGPII
ILSARDRETEKITALDMGADDYVEKPFGIGELLARLRVAMRHRLIRNEASPVVQAGDVSVDLVNRLVTRGGEVIRLSPKE
YDLLAKLLEAGGKVVTHKQLLTAVWGPAHAEDVQYLRVFVGQLRQKLENDPASPKLITTEPGVGYRFYIP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=50.9009009009009, Blast_Score=224, Evalue=3e-60,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.2445414847162, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.375, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=32.1266968325792, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.6306306306306, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=30.8035714285714, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=34.0909090909091, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.9559471365639, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=30.3571428571429, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.6375545851528, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.3185840707965, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=195, Percent_Identity=30.2564102564103, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=24.8888888888889, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=159, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25585; Mature: 25585

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFRPRVLVIDDEPQIHRFLRPALDAAGYEPVRADNATDGLKEIARKVPDAVVLDLGLP
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
DMDGKDVLQKARDFYDGPIIILSARDRETEKITALDMGADDYVEKPFGIGELLARLRVAM
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHHH
RHRLIRNEASPVVQAGDVSVDLVNRLVTRGGEVIRLSPKEYDLLAKLLEAGGKVVTHKQL
HHHHHHCCCCCCEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEEHHHHH
LTAVWGPAHAEDVQYLRVFVGQLRQKLENDPASPKLITTEPGVGYRFYIP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECC
>Mature Secondary Structure
MNAFRPRVLVIDDEPQIHRFLRPALDAAGYEPVRADNATDGLKEIARKVPDAVVLDLGLP
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
DMDGKDVLQKARDFYDGPIIILSARDRETEKITALDMGADDYVEKPFGIGELLARLRVAM
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHHH
RHRLIRNEASPVVQAGDVSVDLVNRLVTRGGEVIRLSPKEYDLLAKLLEAGGKVVTHKQL
HHHHHHCCCCCCEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEEHHHHH
LTAVWGPAHAEDVQYLRVFVGQLRQKLENDPASPKLITTEPGVGYRFYIP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]