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The map label for this gene is cysQ [H]

Identifier: 182678006

GI number: 182678006

Start: 1169523

End: 1170389

Strand: Direct

Name: cysQ [H]

Synonym: Bind_1020

Alternate gene names: 182678006

Gene position: 1169523-1170389 (Clockwise)

Preceding gene: 182678002

Following gene: 182678007

Centisome position: 28.05

GC content: 59.4

Gene sequence:

>867_bases
ATGAACGGCACGAAAATTCAAATGCCTCCTGCCGCGCAACAAAAGGTCGCGTGCGAAGACCGCGATACCATAGCCGAAAT
TTTCGCGGCCATTGCCCTTCGCGCCTCAGTCGAGGTCATGCGGATCTATGCTTCCGATTGCCACGCGAGACGCAAGCCGG
ATCAAAGCCCTGTCTGCGACGCGGATGAACAGGCTGAAGCGATCATTCTCGAACAATTGGCCGTTCGCCTGCCGCATCTG
CCGGTCGTGGCGGAGGAAGCCTCCGCGCGGGGTGACCGGCCGCGTTGCGGTTCGTCTTTCATTCTGGTCGATCCGGTCGA
TGGTACGAAGGAATTTTTGAGCCATACTGGTGAATTCACGATCAATATTGCTTTAATCGAGGCGGGGACACCGATTGCCG
GGGTGGTCTATGCCCCAGCGCTCGACCGGCTGTGGCTCGGCGGCACAAAAGCCTTTGTCTGCACGGTTGCTCCCGGCGGT
GTCTTGCCGCCTGTTTCAGCCCGCCATGCCATTCATGTGCGGCGGGCTCCATCCCATGGCCTGACGGCATTGGCTAGTCG
CTCGCATTCCAATGCCGAGACCGAGGCTTTTCTTGGCCGGCTTGCCATTGCGGAGCGACATTCCGCCGGGTCCTCGCTTA
AATTTTGCGCCGTCGCCGAAGGCGAAGCCGATGTCTATCCCCGTTTCGGTCCGACAATGGAATGGGATACAGCCGCAGGC
GATGCGGTTTTGCGTGCGGCGGGCGGACTCGTCCTTGGCCTCGATAATCAGCCGCTGCATTATGGCAAGGCGACGGAGCT
TTATCGTAATGATTTCTTCATTGCCTGGGGGGATCGCGCGCTCGTTCCCGAAAAGCCGATCGCATGA

Upstream 100 bases:

>100_bases
TTCATATTAACGTTACGCAGTGGCGCGGGATGCATCAGGTCAAAATTCAAGGGGCGAACCAAGGCCTGAAGAGAGACCGG
GTCGAAGCGTGGGGAGCATA

Downstream 100 bases:

>100_bases
GGGGCGGGCCTAGCTTATGGGTTGGGCTCAAGGGCCAAGCTCAAGGGCTTTGGCATATGCGTGAAAATTCATTCTCGTTA
TAATCATTCGTTAACCGTTT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNGTKIQMPPAAQQKVACEDRDTIAEIFAAIALRASVEVMRIYASDCHARRKPDQSPVCDADEQAEAIILEQLAVRLPHL
PVVAEEASARGDRPRCGSSFILVDPVDGTKEFLSHTGEFTINIALIEAGTPIAGVVYAPALDRLWLGGTKAFVCTVAPGG
VLPPVSARHAIHVRRAPSHGLTALASRSHSNAETEAFLGRLAIAERHSAGSSLKFCAVAEGEADVYPRFGPTMEWDTAAG
DAVLRAAGGLVLGLDNQPLHYGKATELYRNDFFIAWGDRALVPEKPIA

Sequences:

>Translated_288_residues
MNGTKIQMPPAAQQKVACEDRDTIAEIFAAIALRASVEVMRIYASDCHARRKPDQSPVCDADEQAEAIILEQLAVRLPHL
PVVAEEASARGDRPRCGSSFILVDPVDGTKEFLSHTGEFTINIALIEAGTPIAGVVYAPALDRLWLGGTKAFVCTVAPGG
VLPPVSARHAIHVRRAPSHGLTALASRSHSNAETEAFLGRLAIAERHSAGSSLKFCAVAEGEADVYPRFGPTMEWDTAAG
DAVLRAAGGLVLGLDNQPLHYGKATELYRNDFFIAWGDRALVPEKPIA
>Mature_288_residues
MNGTKIQMPPAAQQKVACEDRDTIAEIFAAIALRASVEVMRIYASDCHARRKPDQSPVCDADEQAEAIILEQLAVRLPHL
PVVAEEASARGDRPRCGSSFILVDPVDGTKEFLSHTGEFTINIALIEAGTPIAGVVYAPALDRLWLGGTKAFVCTVAPGG
VLPPVSARHAIHVRRAPSHGLTALASRSHSNAETEAFLGRLAIAERHSAGSSLKFCAVAEGEADVYPRFGPTMEWDTAAG
DAVLRAAGGLVLGLDNQPLHYGKATELYRNDFFIAWGDRALVPEKPIA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=238, Percent_Identity=42.0168067226891, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995905, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=248, Percent_Identity=26.2096774193548, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320493, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30752; Mature: 30752

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTKIQMPPAAQQKVACEDRDTIAEIFAAIALRASVEVMRIYASDCHARRKPDQSPVCD
CCCCEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ADEQAEAIILEQLAVRLPHLPVVAEEASARGDRPRCGSSFILVDPVDGTKEFLSHTGEFT
CCHHHHHHHHHHHHHHCCCCCEEECHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEE
INIALIEAGTPIAGVVYAPALDRLWLGGTKAFVCTVAPGGVLPPVSARHAIHVRRAPSHG
EEEEEEECCCCEEEEEECCHHHHEEECCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCC
LTALASRSHSNAETEAFLGRLAIAERHSAGSSLKFCAVAEGEADVYPRFGPTMEWDTAAG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
DAVLRAAGGLVLGLDNQPLHYGKATELYRNDFFIAWGDRALVPEKPIA
HHHHHHCCCEEEECCCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNGTKIQMPPAAQQKVACEDRDTIAEIFAAIALRASVEVMRIYASDCHARRKPDQSPVCD
CCCCEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ADEQAEAIILEQLAVRLPHLPVVAEEASARGDRPRCGSSFILVDPVDGTKEFLSHTGEFT
CCHHHHHHHHHHHHHHCCCCCEEECHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEE
INIALIEAGTPIAGVVYAPALDRLWLGGTKAFVCTVAPGGVLPPVSARHAIHVRRAPSHG
EEEEEEECCCCEEEEEECCHHHHEEECCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCC
LTALASRSHSNAETEAFLGRLAIAERHSAGSSLKFCAVAEGEADVYPRFGPTMEWDTAAG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
DAVLRAAGGLVLGLDNQPLHYGKATELYRNDFFIAWGDRALVPEKPIA
HHHHHHCCCEEEECCCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]