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The map label for this gene is pqqL [C]

Identifier: 182677995

GI number: 182677995

Start: 1157789

End: 1159195

Strand: Direct

Name: pqqL [C]

Synonym: Bind_1009

Alternate gene names: 182677995

Gene position: 1157789-1159195 (Clockwise)

Preceding gene: 182677994

Following gene: 182677996

Centisome position: 27.76

GC content: 59.63

Gene sequence:

>1407_bases
ATGAAAGCGATGGTCTGCATGTCTCAGGGTCAGTCGAGCGCGGCATCACCTGTTCAAGGTTCTTTCGGCCTCACCCCTTC
GCCAGCCAATCCGGCCAAGGCCCATGGGCCGCAAGTCAGTCAGGCGAAGCTCGCCAATGGCATGGACATTGTGGTCATTC
CTGACCATCGCGCGCCTGTCATCACCCATATGGTCTGGTATCGTAACGGGTCCGCCGATGATCCAGTGGGCAAGTCCGGC
ATTGCGCATTTCCTTGAACATCTCATGTTCAAGGGCACCAAGGATCACAAACAGGGCGAATTTTCCGAAGTGATCGCCGA
TTTCGGCGGTCAGGAAAACGCCTTCACCTCGAATGATTATACCGCCTATTTCCAGCGGGTCGCCAAGGACCATCTCCGCG
TCTGCATGAATTACGAGGCTGACCGGATGAAAAATCTGGTCCTCTCCGATGAAGTGGTCGCCCCCGAGCGCGATGTCGTG
CTCGAGGAGCGCCGCATGCGCACGGATTCCGATCCCTCGGACCTTCTGAACGAGGCAGTCCAGGCCGCCCTTTATACGCA
TCATCCCTATGGCAAGCCGATCATCGGTTGGAGCCATGAGATCGAAACCCTCGATCGCCAGGATGCGTTTGCCTATTACG
ATCGTTTCTATACGCCAGAAAATGCGATTCTCGTCGTCGCCGGCGATGTCGAGCCCGATGAGGTTCTGGCGCTTGCCGAG
GATGTCTATGGCAAGATCCCGGCCCATGGCGAGGCGCCGCGTCGCTCGCGTCCCCGTGAGCCCGAGCCGCGCGCTCATCG
GCTCGTCAAGCTCGTCGATGAAAAGGTCGAACAGCCGACGCATCAGGGGGTCTTCCTCGTCCCGTCCTACAAGACGGCCG
CGCCTGGCGAAGCGGAAGCGCTTGAAGTTCTCGGCCATTTGCTGGGCGGCGGTCAGACCAGCCTGTTGTTCAAAAAGCTC
GTCGTGGCCGATAAAGTCGCCGTTGCCGCCGGCGCCCATTACCAGGGGACGGCTGTCGATCAGACGCGCTTCTATGTTTA
TGGCATCCCGGCGCCAGGCATTACGCTCGAGGAAATCGACAATGCCATTGACGCCGTCATTGCCCATGTGGCCAAGGAAG
GCGTCTCGGAAGCGGATCTGCGTCGCACCAAGACCCGACTCGTCGCAGAGGCGATCTATGCCCAGGATAATCAATCGACA
TTGGCGCGGTGGTATGGCGCTTCGCTCAGCGTTGGCCTGACCCTGAACGATATTGCCGAATGGCCGGCGCGAATCGAGGC
CGTTACCCTGGAGGATGTCAAGAAAGCCACGCGCTGGCTCGCCAAAAGGCGCGGCGTTACGGGTTTCCTCCTGCCGGCCC
ATGCCCCAGGAGAACATACGATCGAGGTCGAGACCGAGGCCAGTTGA

Upstream 100 bases:

>100_bases
AAGGTTGCAATGAATGGTCCCGCGAAGGATGCGCGGGAAGATGCATAACAGGCAGGTAACAGCCTCGTGCCACAAGCGTG
GCGTAGGCGCCTGCGAGTGA

Downstream 100 bases:

>100_bases
ACCGGCCTTCTGGTTGCGCCCGCTTCCTGTTGATGCCAGGGTCAGATGATCCGTGCTGATCGGGTGCATAATTCGTAGCT
CCTCATGGCAGGTCGCCATC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKAMVCMSQGQSSAASPVQGSFGLTPSPANPAKAHGPQVSQAKLANGMDIVVIPDHRAPVITHMVWYRNGSADDPVGKSG
IAHFLEHLMFKGTKDHKQGEFSEVIADFGGQENAFTSNDYTAYFQRVAKDHLRVCMNYEADRMKNLVLSDEVVAPERDVV
LEERRMRTDSDPSDLLNEAVQAALYTHHPYGKPIIGWSHEIETLDRQDAFAYYDRFYTPENAILVVAGDVEPDEVLALAE
DVYGKIPAHGEAPRRSRPREPEPRAHRLVKLVDEKVEQPTHQGVFLVPSYKTAAPGEAEALEVLGHLLGGGQTSLLFKKL
VVADKVAVAAGAHYQGTAVDQTRFYVYGIPAPGITLEEIDNAIDAVIAHVAKEGVSEADLRRTKTRLVAEAIYAQDNQST
LARWYGASLSVGLTLNDIAEWPARIEAVTLEDVKKATRWLAKRRGVTGFLLPAHAPGEHTIEVETEAS

Sequences:

>Translated_468_residues
MKAMVCMSQGQSSAASPVQGSFGLTPSPANPAKAHGPQVSQAKLANGMDIVVIPDHRAPVITHMVWYRNGSADDPVGKSG
IAHFLEHLMFKGTKDHKQGEFSEVIADFGGQENAFTSNDYTAYFQRVAKDHLRVCMNYEADRMKNLVLSDEVVAPERDVV
LEERRMRTDSDPSDLLNEAVQAALYTHHPYGKPIIGWSHEIETLDRQDAFAYYDRFYTPENAILVVAGDVEPDEVLALAE
DVYGKIPAHGEAPRRSRPREPEPRAHRLVKLVDEKVEQPTHQGVFLVPSYKTAAPGEAEALEVLGHLLGGGQTSLLFKKL
VVADKVAVAAGAHYQGTAVDQTRFYVYGIPAPGITLEEIDNAIDAVIAHVAKEGVSEADLRRTKTRLVAEAIYAQDNQST
LARWYGASLSVGLTLNDIAEWPARIEAVTLEDVKKATRWLAKRRGVTGFLLPAHAPGEHTIEVETEAS
>Mature_468_residues
MKAMVCMSQGQSSAASPVQGSFGLTPSPANPAKAHGPQVSQAKLANGMDIVVIPDHRAPVITHMVWYRNGSADDPVGKSG
IAHFLEHLMFKGTKDHKQGEFSEVIADFGGQENAFTSNDYTAYFQRVAKDHLRVCMNYEADRMKNLVLSDEVVAPERDVV
LEERRMRTDSDPSDLLNEAVQAALYTHHPYGKPIIGWSHEIETLDRQDAFAYYDRFYTPENAILVVAGDVEPDEVLALAE
DVYGKIPAHGEAPRRSRPREPEPRAHRLVKLVDEKVEQPTHQGVFLVPSYKTAAPGEAEALEVLGHLLGGGQTSLLFKKL
VVADKVAVAAGAHYQGTAVDQTRFYVYGIPAPGITLEEIDNAIDAVIAHVAKEGVSEADLRRTKTRLVAEAIYAQDNQST
LARWYGASLSVGLTLNDIAEWPARIEAVTLEDVKKATRWLAKRRGVTGFLLPAHAPGEHTIEVETEAS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=211, Percent_Identity=28.9099526066351, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI94538354, Length=219, Percent_Identity=29.2237442922374, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI155969707, Length=326, Percent_Identity=24.8466257668712, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787770, Length=243, Percent_Identity=27.9835390946502, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI2367164, Length=218, Percent_Identity=25.2293577981651, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=417, Percent_Identity=23.5011990407674, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17553678, Length=248, Percent_Identity=28.2258064516129, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=386, Percent_Identity=23.8341968911917, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323421, Length=306, Percent_Identity=24.5098039215686, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357875, Length=212, Percent_Identity=28.3018867924528, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646943, Length=212, Percent_Identity=28.3018867924528, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51286; Mature: 51286

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMVCMSQGQSSAASPVQGSFGLTPSPANPAKAHGPQVSQAKLANGMDIVVIPDHRAPV
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCH
ITHMVWYRNGSADDPVGKSGIAHFLEHLMFKGTKDHKQGEFSEVIADFGGQENAFTSNDY
HHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
TAYFQRVAKDHLRVCMNYEADRMKNLVLSDEVVAPERDVVLEERRMRTDSDPSDLLNEAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
QAALYTHHPYGKPIIGWSHEIETLDRQDAFAYYDRFYTPENAILVVAGDVEPDEVLALAE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
DVYGKIPAHGEAPRRSRPREPEPRAHRLVKLVDEKVEQPTHQGVFLVPSYKTAAPGEAEA
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHH
LEVLGHLLGGGQTSLLFKKLVVADKVAVAAGAHYQGTAVDQTRFYVYGIPAPGITLEEID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEECCCCCCCHHHHH
NAIDAVIAHVAKEGVSEADLRRTKTRLVAEAIYAQDNQSTLARWYGASLSVGLTLNDIAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHH
WPARIEAVTLEDVKKATRWLAKRRGVTGFLLPAHAPGEHTIEVETEAS
CCHHEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MKAMVCMSQGQSSAASPVQGSFGLTPSPANPAKAHGPQVSQAKLANGMDIVVIPDHRAPV
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCH
ITHMVWYRNGSADDPVGKSGIAHFLEHLMFKGTKDHKQGEFSEVIADFGGQENAFTSNDY
HHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
TAYFQRVAKDHLRVCMNYEADRMKNLVLSDEVVAPERDVVLEERRMRTDSDPSDLLNEAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
QAALYTHHPYGKPIIGWSHEIETLDRQDAFAYYDRFYTPENAILVVAGDVEPDEVLALAE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
DVYGKIPAHGEAPRRSRPREPEPRAHRLVKLVDEKVEQPTHQGVFLVPSYKTAAPGEAEA
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHH
LEVLGHLLGGGQTSLLFKKLVVADKVAVAAGAHYQGTAVDQTRFYVYGIPAPGITLEEID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEECCCCCCCHHHHH
NAIDAVIAHVAKEGVSEADLRRTKTRLVAEAIYAQDNQSTLARWYGASLSVGLTLNDIAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHH
WPARIEAVTLEDVKKATRWLAKRRGVTGFLLPAHAPGEHTIEVETEAS
CCHHEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]