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The map label for this gene is murB

Identifier: 182677687

GI number: 182677687

Start: 776915

End: 777847

Strand: Direct

Name: murB

Synonym: Bind_0694

Alternate gene names: 182677687

Gene position: 776915-777847 (Clockwise)

Preceding gene: 182677686

Following gene: 182677688

Centisome position: 18.63

GC content: 57.66

Gene sequence:

>933_bases
ATGTTTGCCGATCTCATTCCGCGTCTGAGGGACGCCATGCCGGAATTGCGCGGTGAATTGCAGACCAATGTGCCGCTTGC
GCCCTGGACATGGTTCAAAACCGGCGGGCCGGCGCAATGTGTCTATGTCGCGCCGGATGTCGAGGATCTCGCTTATTTCC
TCGGCAATCTCGACCCGGATATTTCAATCTTCGTCTTAGGGCTCGGCTCGAATATTCTTGTGCGCGATGGCGGCATTGAA
GGTGTCGTCATCAGTTTCGGTCCGTCTTTCCACAAAATCGTGATTGAAGGCGATACGATCAGCGCCGGTGCCGCTGTTGC
TGATGTGAAACTTGCCAGCGCCGCCGCCATGGCGGGTCTCGGCGGTTTCGCTTTTTTGCGTGGCATTCCGGGTACGATCG
GCGGTGCCTTGCGCATGAATGCAGGGGCTTTTGGTGGGACGATCGCTGATATTCTCGTCTCTTGCGAAGGCCTCGACCGG
CGTGGCGCCTTGCACCATTTCACGCCGGAGGAAATGGGCTTTTCCTACCGCCATTGCGCCGTGGAAGGCATTATTTTCAC
GCAAGGACTGTTTGCGGGCTGGCCGGAAAATCCCGAAAAGATCCGCGAGGATATGGGAAAGATCGCGCAGGAGCGCGCCA
AGACGCAGCCGGTCAATACGCGGACCGGCGGTTCGACCTTCAAGAATCCCAATGGTGCGAAAGCCTGGGAATTGATTGAT
CGCGCCGGCTGCCGTGGCCTGACGCTAGGTGATGCGCAAGTCTCTGAGCTGCATTGTAATTTTCTCGTCAATCGCGGCAA
GGCGAGCGCCGCGGATATCGAAAATCTTGGTGAGATGGTGCGCCAGAAGGTGCTGGCCGAAACGGGTGTGGAACTCGAAT
GGGAAATCCTGCGGGTTGGTCGGCCGCCCGTTGCTCATAAAACTTCACGCTGA

Upstream 100 bases:

>100_bases
CCCGGTGACTATGTCGTGTGTTTAGGGGCCGGCAATATTACGCAATGGGCCTATGCGCTTCCTGGTCAGCTTGCCGCGCC
TGTCAGCAAGGCCTCCTGAA

Downstream 100 bases:

>100_bases
CTGAAGGAGAAGCGGATCGTGGCGAAACATGTGGCCGTGCTGATGGGCGGTCTTTCGGCCGAGCGCGAGGTCTCGCTGTG
CTCGGGGGCGGCTTGTGCTG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFADLIPRLRDAMPELRGELQTNVPLAPWTWFKTGGPAQCVYVAPDVEDLAYFLGNLDPDISIFVLGLGSNILVRDGGIE
GVVISFGPSFHKIVIEGDTISAGAAVADVKLASAAAMAGLGGFAFLRGIPGTIGGALRMNAGAFGGTIADILVSCEGLDR
RGALHHFTPEEMGFSYRHCAVEGIIFTQGLFAGWPENPEKIREDMGKIAQERAKTQPVNTRTGGSTFKNPNGAKAWELID
RAGCRGLTLGDAQVSELHCNFLVNRGKASAADIENLGEMVRQKVLAETGVELEWEILRVGRPPVAHKTSR

Sequences:

>Translated_310_residues
MFADLIPRLRDAMPELRGELQTNVPLAPWTWFKTGGPAQCVYVAPDVEDLAYFLGNLDPDISIFVLGLGSNILVRDGGIE
GVVISFGPSFHKIVIEGDTISAGAAVADVKLASAAAMAGLGGFAFLRGIPGTIGGALRMNAGAFGGTIADILVSCEGLDR
RGALHHFTPEEMGFSYRHCAVEGIIFTQGLFAGWPENPEKIREDMGKIAQERAKTQPVNTRTGGSTFKNPNGAKAWELID
RAGCRGLTLGDAQVSELHCNFLVNRGKASAADIENLGEMVRQKVLAETGVELEWEILRVGRPPVAHKTSR
>Mature_310_residues
MFADLIPRLRDAMPELRGELQTNVPLAPWTWFKTGGPAQCVYVAPDVEDLAYFLGNLDPDISIFVLGLGSNILVRDGGIE
GVVISFGPSFHKIVIEGDTISAGAAVADVKLASAAAMAGLGGFAFLRGIPGTIGGALRMNAGAFGGTIADILVSCEGLDR
RGALHHFTPEEMGFSYRHCAVEGIIFTQGLFAGWPENPEKIREDMGKIAQERAKTQPVNTRTGGSTFKNPNGAKAWELID
RAGCRGLTLGDAQVSELHCNFLVNRGKASAADIENLGEMVRQKVLAETGVELEWEILRVGRPPVAHKTSR

Specific function: Cell wall formation

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURB_BEII9 (B2IGG2)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831833.1
- GeneID:   6198673
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0694
- HOGENOM:   HBG686573
- OMA:   LESSKIP
- GO:   GO:0005737
- HAMAP:   MF_00037
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094
- Gene3D:   G3DSA:3.30.465.10
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.90.78.10
- PANTHER:   PTHR21071
- TIGRFAMs:   TIGR00179

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C; SSF56176 FAD-binding_2; SSF56194 MurB_C

EC number: =1.1.1.158

Molecular weight: Translated: 33141; Mature: 33141

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS51387 FAD_PCMH

Important sites: ACT_SITE 177-177 ACT_SITE 225-225 ACT_SITE 295-295

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFADLIPRLRDAMPELRGELQTNVPLAPWTWFKTGGPAQCVYVAPDVEDLAYFLGNLDPD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHCCCCCC
ISIFVLGLGSNILVRDGGIEGVVISFGPSFHKIVIEGDTISAGAAVADVKLASAAAMAGL
EEEEEEEECCEEEEECCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHC
GGFAFLRGIPGTIGGALRMNAGAFGGTIADILVSCEGLDRRGALHHFTPEEMGFSYRHCA
CHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHH
VEGIIFTQGLFAGWPENPEKIREDMGKIAQERAKTQPVNTRTGGSTFKNPNGAKAWELID
HHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
RAGCRGLTLGDAQVSELHCNFLVNRGKASAADIENLGEMVRQKVLAETGVELEWEILRVG
HCCCCCEEECCCHHHHHHEEHEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
RPPVAHKTSR
CCCCCCCCCC
>Mature Secondary Structure
MFADLIPRLRDAMPELRGELQTNVPLAPWTWFKTGGPAQCVYVAPDVEDLAYFLGNLDPD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHCCCCCC
ISIFVLGLGSNILVRDGGIEGVVISFGPSFHKIVIEGDTISAGAAVADVKLASAAAMAGL
EEEEEEEECCEEEEECCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHC
GGFAFLRGIPGTIGGALRMNAGAFGGTIADILVSCEGLDRRGALHHFTPEEMGFSYRHCA
CHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHH
VEGIIFTQGLFAGWPENPEKIREDMGKIAQERAKTQPVNTRTGGSTFKNPNGAKAWELID
HHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
RAGCRGLTLGDAQVSELHCNFLVNRGKASAADIENLGEMVRQKVLAETGVELEWEILRVG
HCCCCCEEECCCHHHHHHEEHEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
RPPVAHKTSR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA