| Definition | Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome. |
|---|---|
| Accession | NC_010581 |
| Length | 4,170,153 |
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The map label for this gene is murE [H]
Identifier: 182677680
GI number: 182677680
Start: 767634
End: 769094
Strand: Direct
Name: murE [H]
Synonym: Bind_0687
Alternate gene names: 182677680
Gene position: 767634-769094 (Clockwise)
Preceding gene: 182677679
Following gene: 182677681
Centisome position: 18.41
GC content: 62.22
Gene sequence:
>1461_bases ATGCGGCTTGATGCACTCTTCCCCGATGCATTAATCGAACCGCCGGCTTTTGGTGCGCGTGAGATCGCTGGCCTTGCCTG TGACAGCCGATTGGTTGCCAAGGATCAAGTCTTTTTCGCCGTTCCTGGCACCAAGGCGGATGGTTTGACCTATGCGCCCG AGGCGGTGCGGCGTGGTGCCTTGGCCGTCGTCACGGAACAATCCGCATCGGTGCCGTTCGAAACGGCGGCTCTGGTCAAA GTCGCGGATGTTCGTTCCGCGCTCGCGATTGCCTCGGCCCGTTTCTATGCGCGCCAGCCTGAAACCGTGGTTGCGGTGAC GGGGACCAGCGGCAAGACATCGGTCGCAGCCTTTGCCCGGCAGATCTGGGCCAGCCTGGGGTTCAAGGCCGCTTCTGTCG GCACTTTGGGCGTCGTGGCCCCGGATGGCGCGAGCTATGGCGGTCTGACGACGCCTGATCCGATCAGCCTGCATCGCACG CTCGATGAATTGGCCGGCGCCGGCGTGACGCATCTTGCCTTGGAAGCGTCCTCGCACGGGCTCGATCAGCATCGGCTGGA TTATGTGCGGCTGAAGGCGGCGGGTTTCACCAATCTCTCGCGCGATCATCTCGATTATCATCCGACCCTCGAAGCCTATT TCCAGGCGAAGCTCCTGCTCTTCACCCATGTCTTGCCGGCTGACGGCACGGTGGTGGTCGATGCCGACAGTTCCGCCGGC CATGAGGTGATCGATGTCGCCAAGGCGCGCGGGCTGAAGGTCTTTTCCTTAGGGTTTGCGGGCGAGACACTGCACCTCCT CGAGGCCAGACCCGAGGCGGCGGCGACTTTGCTGCGCTTGACCTTCGCAGGCAAGGATTGGGCCTTGCGCCTGCCTCTGG TTGGGAGTTTCCAAGCTGCCAATGCCTTGATGGCGGCTGGCCTTTGCATCAGCACCGGCGCTGCGCCGGACGCGGTTTTT GCCGCGCTTGAAAGGCTCGAAGGTGCCCCTGGCCGCCTCGAAAAGGTCGGTGAACGGCGTGGTGCGTCCATTTTCGTCGA TTATGCCCACAAGCCCGATGCGCTGGAAAAAGCCTTGCAGGCCTTGCGGCCCTTCACGCAAAAGAGGCTGATCGTGATTT TCGGGTGTGGTGGCGATCGCGATGCCGGCAAGCGGCCCCTGATGGGTGAAATCGCTGCGCGGCTCGCCGATCATGTCATT GTCACCGATGACAATCCGCGCAGCGAGGATCCAGATCTCATTCGCAAGGCCATTCTGCAAGGGGCTGGTTCAGGTCCTCA TATTCGCGAGATCGGCGATCGCGAGGCGGCGATCAAAAGCGGAATTGGCATGCTGGAGCCCGGCGATCTTCTGCTGATTG CTGGCAAGGGCCATGAAACCGGCCAGATCCTGGCTGACAGGACGCTGCCCTTTTCCGATCGCGATTGCGCCCGCGCGGCG CTTGAGGACCATGCTGCATGA
Upstream 100 bases:
>100_bases TTCCGCCGCGTCTCGAATTGCCGACACAGCCTTTCCCGCTGCTCGCCAAGCTCGGCTATGGCATCGCCAATGTTCCCCAG ACGAGTCGGGGAGAGCATTG
Downstream 100 bases:
>100_bases ACGAGATTTTGATGCCCGAAAGCGTCGATAAGGAGATTTTGTGGACGCCGCTCGGTCTCGTCACGCCTTTGCAGGCCCGT GTCAGTGGTCATGTTCCGTT
Product: UDP-N-acetylmuramyl-tripeptide synthetase
Products: NA
Alternate protein names: Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase [H]
Number of amino acids: Translated: 486; Mature: 486
Protein sequence:
>486_residues MRLDALFPDALIEPPAFGAREIAGLACDSRLVAKDQVFFAVPGTKADGLTYAPEAVRRGALAVVTEQSASVPFETAALVK VADVRSALAIASARFYARQPETVVAVTGTSGKTSVAAFARQIWASLGFKAASVGTLGVVAPDGASYGGLTTPDPISLHRT LDELAGAGVTHLALEASSHGLDQHRLDYVRLKAAGFTNLSRDHLDYHPTLEAYFQAKLLLFTHVLPADGTVVVDADSSAG HEVIDVAKARGLKVFSLGFAGETLHLLEARPEAAATLLRLTFAGKDWALRLPLVGSFQAANALMAAGLCISTGAAPDAVF AALERLEGAPGRLEKVGERRGASIFVDYAHKPDALEKALQALRPFTQKRLIVIFGCGGDRDAGKRPLMGEIAARLADHVI VTDDNPRSEDPDLIRKAILQGAGSGPHIREIGDREAAIKSGIGMLEPGDLLLIAGKGHETGQILADRTLPFSDRDCARAA LEDHAA
Sequences:
>Translated_486_residues MRLDALFPDALIEPPAFGAREIAGLACDSRLVAKDQVFFAVPGTKADGLTYAPEAVRRGALAVVTEQSASVPFETAALVK VADVRSALAIASARFYARQPETVVAVTGTSGKTSVAAFARQIWASLGFKAASVGTLGVVAPDGASYGGLTTPDPISLHRT LDELAGAGVTHLALEASSHGLDQHRLDYVRLKAAGFTNLSRDHLDYHPTLEAYFQAKLLLFTHVLPADGTVVVDADSSAG HEVIDVAKARGLKVFSLGFAGETLHLLEARPEAAATLLRLTFAGKDWALRLPLVGSFQAANALMAAGLCISTGAAPDAVF AALERLEGAPGRLEKVGERRGASIFVDYAHKPDALEKALQALRPFTQKRLIVIFGCGGDRDAGKRPLMGEIAARLADHVI VTDDNPRSEDPDLIRKAILQGAGSGPHIREIGDREAAIKSGIGMLEPGDLLLIAGKGHETGQILADRTLPFSDRDCARAA LEDHAA >Mature_486_residues MRLDALFPDALIEPPAFGAREIAGLACDSRLVAKDQVFFAVPGTKADGLTYAPEAVRRGALAVVTEQSASVPFETAALVK VADVRSALAIASARFYARQPETVVAVTGTSGKTSVAAFARQIWASLGFKAASVGTLGVVAPDGASYGGLTTPDPISLHRT LDELAGAGVTHLALEASSHGLDQHRLDYVRLKAAGFTNLSRDHLDYHPTLEAYFQAKLLLFTHVLPADGTVVVDADSSAG HEVIDVAKARGLKVFSLGFAGETLHLLEARPEAAATLLRLTFAGKDWALRLPLVGSFQAANALMAAGLCISTGAAPDAVF AALERLEGAPGRLEKVGERRGASIFVDYAHKPDALEKALQALRPFTQKRLIVIFGCGGDRDAGKRPLMGEIAARLADHVI VTDDNPRSEDPDLIRKAILQGAGSGPHIREIGDREAAIKSGIGMLEPGDLLLIAGKGHETGQILADRTLPFSDRDCARAA LEDHAA
Specific function: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan [H]
COG id: COG0769
COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family. MurE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786273, Length=477, Percent_Identity=34.3815513626834, Blast_Score=226, Evalue=2e-60,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005761 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.13 [H]
Molecular weight: Translated: 51130; Mature: 51130
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLDALFPDALIEPPAFGAREIAGLACDSRLVAKDQVFFAVPGTKADGLTYAPEAVRRGA CCCCCCCCHHHCCCCCCCHHHHHHHCCCCCEEECCEEEEEECCCCCCCCEECHHHHHCCE LAVVTEQSASVPFETAALVKVADVRSALAIASARFYARQPETVVAVTGTSGKTSVAAFAR EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH QIWASLGFKAASVGTLGVVAPDGASYGGLTTPDPISLHRTLDELAGAGVTHLALEASSHG HHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCC LDQHRLDYVRLKAAGFTNLSRDHLDYHPTLEAYFQAKLLLFTHVLPADGTVVVDADSSAG CCHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC HEVIDVAKARGLKVFSLGFAGETLHLLEARPEAAATLLRLTFAGKDWALRLPLVGSFQAA HHHHHHHHHCCCEEEEECCCCCEEEEHHCCCHHHHHEEHEEECCCCEEEECCCCCCHHHH NALMAAGLCISTGAAPDAVFAALERLEGAPGRLEKVGERRGASIFVDYAHKPDALEKALQ HHHHHHCHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHH ALRPFTQKRLIVIFGCGGDRDAGKRPLMGEIAARLADHVIVTDDNPRSEDPDLIRKAILQ HHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHH GAGSGPHIREIGDREAAIKSGIGMLEPGDLLLIAGKGHETGQILADRTLPFSDRDCARAA CCCCCCCHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHH LEDHAA HHHCCC >Mature Secondary Structure MRLDALFPDALIEPPAFGAREIAGLACDSRLVAKDQVFFAVPGTKADGLTYAPEAVRRGA CCCCCCCCHHHCCCCCCCHHHHHHHCCCCCEEECCEEEEEECCCCCCCCEECHHHHHCCE LAVVTEQSASVPFETAALVKVADVRSALAIASARFYARQPETVVAVTGTSGKTSVAAFAR EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH QIWASLGFKAASVGTLGVVAPDGASYGGLTTPDPISLHRTLDELAGAGVTHLALEASSHG HHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCC LDQHRLDYVRLKAAGFTNLSRDHLDYHPTLEAYFQAKLLLFTHVLPADGTVVVDADSSAG CCHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC HEVIDVAKARGLKVFSLGFAGETLHLLEARPEAAATLLRLTFAGKDWALRLPLVGSFQAA HHHHHHHHHCCCEEEEECCCCCEEEEHHCCCHHHHHEEHEEECCCCEEEECCCCCCHHHH NALMAAGLCISTGAAPDAVFAALERLEGAPGRLEKVGERRGASIFVDYAHKPDALEKALQ HHHHHHCHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHH ALRPFTQKRLIVIFGCGGDRDAGKRPLMGEIAARLADHVIVTDDNPRSEDPDLIRKAILQ HHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHH GAGSGPHIREIGDREAAIKSGIGMLEPGDLLLIAGKGHETGQILADRTLPFSDRDCARAA CCCCCCCHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHH LEDHAA HHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12597275 [H]