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The map label for this gene is namA [H]

Identifier: 182677648

GI number: 182677648

Start: 737765

End: 738868

Strand: Direct

Name: namA [H]

Synonym: Bind_0655

Alternate gene names: 182677648

Gene position: 737765-738868 (Clockwise)

Preceding gene: 182677647

Following gene: 182677649

Centisome position: 17.69

GC content: 60.96

Gene sequence:

>1104_bases
ATGAGCACGCCATACCTCTTCACGCCTTTTCAGGTCGGTTCCTTGGCGCTGACCAATCGCATTATCATCGCGCCAATGTG
CCAATATTCGGCCGTGGATGGCGTCGCGCAGGATTGGCATCTCATCCATCTCGGCAATCTGGCTCTGTCTGGCGCCGCCC
TATTGACCATTGAGGCGACGGCGGTTTTGCCCGAGGGCCGCATTTCCTATGCGGATATTGGCCTCTGGGACGATGTGACA
GAAGCCGCCCTGCGCCGCACGCTGGACGGTGTTCGCCGCTATTCCGATATGCCGATCGGGATGCAGCTTGCACATGCGGG
ACGCAAGGCTTCGACCGATCTGCCCTGGAAGGGTGGGGCCAAAATCGCCGCCGATAAACCCAATGGCTGGCAAACGGTCG
CGCCCTCGGCCGTCGCTCTTCATAAAGGCGACACGCCACCCACAGCGCTCGACAAGGATGGACTGATCCGTGTCCGCGAG
GCCTTTGCGGAGGCCGCGAAGCGCGCCGGCCGTCTTGGCATCGATCTCGTGCAGATCCATGCCGCGCATGGCTATTTGCT
GCACCAATTTCTGTCGCCGATTTCCAACCAGCGCACGGATGACTATGGCGGCAGTCTCGAAAACCGGATGCGTTTCCCCC
TGGAAGTGTTCGATGCCGTGCGGGCGGCCTTTCCGGCCGGACGGCCGGTGAGCGTTCGGGTTTCTGGCACGGATTGGGTC
GAGGGTGGCTGGGAGGTCGAGCAGACCATTGCTTTCGCCAAGGCGCTCGAAGCGCGGGGATGCGACGCCATTCATGTTTC
GAGTGGCGGTCTCGCCGCGGAACAGAAGATCCCGATCGGTCCGAGCTATCAGGTGCCGCTTGCTCGAGCTGTCAAGGCGG
CCGTCAAAATACCGGTTGTCGCGGTCGGTCTCATCACCGGCTATGAACAGGCCGAGGCAATTGTCAGTACGGGCGACGCG
GATCTGATCGCGCTCGCAAGGGCTATTCTTTATAATCCGCGTTGGCCTTGGCATGCGGCCGCCTATTTCGGCGCCCATGT
CAAAGCGCCGCCGCAATATTTGCGTTCGCAGCCGCATCAATTTCGCGACTTGTTTCTCAGTTGA

Upstream 100 bases:

>100_bases
ATTCGCACGGCCTTGTCTCTTCACGGAATCCTGACTACCGGACCTCGTGCTGATCATGCGATCCTTCCACAAATGAAACA
GGGAACATCCAGGGAAAGCC

Downstream 100 bases:

>100_bases
GAGGAACGACTGGGCCGTAACTGACTTTAATACAAGTGGCCAAAAGACTGAAAGAAGAAGCCCGGGGGGGGGGGGGATAT
GGCGGAAATGATCGTCGTTG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSTPYLFTPFQVGSLALTNRIIIAPMCQYSAVDGVAQDWHLIHLGNLALSGAALLTIEATAVLPEGRISYADIGLWDDVT
EAALRRTLDGVRRYSDMPIGMQLAHAGRKASTDLPWKGGAKIAADKPNGWQTVAPSAVALHKGDTPPTALDKDGLIRVRE
AFAEAAKRAGRLGIDLVQIHAAHGYLLHQFLSPISNQRTDDYGGSLENRMRFPLEVFDAVRAAFPAGRPVSVRVSGTDWV
EGGWEVEQTIAFAKALEARGCDAIHVSSGGLAAEQKIPIGPSYQVPLARAVKAAVKIPVVAVGLITGYEQAEAIVSTGDA
DLIALARAILYNPRWPWHAAAYFGAHVKAPPQYLRSQPHQFRDLFLS

Sequences:

>Translated_367_residues
MSTPYLFTPFQVGSLALTNRIIIAPMCQYSAVDGVAQDWHLIHLGNLALSGAALLTIEATAVLPEGRISYADIGLWDDVT
EAALRRTLDGVRRYSDMPIGMQLAHAGRKASTDLPWKGGAKIAADKPNGWQTVAPSAVALHKGDTPPTALDKDGLIRVRE
AFAEAAKRAGRLGIDLVQIHAAHGYLLHQFLSPISNQRTDDYGGSLENRMRFPLEVFDAVRAAFPAGRPVSVRVSGTDWV
EGGWEVEQTIAFAKALEARGCDAIHVSSGGLAAEQKIPIGPSYQVPLARAVKAAVKIPVVAVGLITGYEQAEAIVSTGDA
DLIALARAILYNPRWPWHAAAYFGAHVKAPPQYLRSQPHQFRDLFLS
>Mature_366_residues
STPYLFTPFQVGSLALTNRIIIAPMCQYSAVDGVAQDWHLIHLGNLALSGAALLTIEATAVLPEGRISYADIGLWDDVTE
AALRRTLDGVRRYSDMPIGMQLAHAGRKASTDLPWKGGAKIAADKPNGWQTVAPSAVALHKGDTPPTALDKDGLIRVREA
FAEAAKRAGRLGIDLVQIHAAHGYLLHQFLSPISNQRTDDYGGSLENRMRFPLEVFDAVRAAFPAGRPVSVRVSGTDWVE
GGWEVEQTIAFAKALEARGCDAIHVSSGGLAAEQKIPIGPSYQVPLARAVKAAVKIPVVAVGLITGYEQAEAIVSTGDAD
LIALARAILYNPRWPWHAAAYFGAHVKAPPQYLRSQPHQFRDLFLS

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=351, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789463, Length=338, Percent_Identity=28.4023668639053, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=249, Percent_Identity=34.5381526104418, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=250, Percent_Identity=29.2, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=191, Percent_Identity=34.5549738219895, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=280, Percent_Identity=31.0714285714286, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=174, Percent_Identity=35.632183908046, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=192, Percent_Identity=32.8125, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=218, Percent_Identity=30.7339449541284, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=220, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39537; Mature: 39405

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPYLFTPFQVGSLALTNRIIIAPMCQYSAVDGVAQDWHLIHLGNLALSGAALLTIEAT
CCCCEEECCCCCCCEEHHCCEEEEECHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEE
AVLPEGRISYADIGLWDDVTEAALRRTLDGVRRYSDMPIGMQLAHAGRKASTDLPWKGGA
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCC
KIAADKPNGWQTVAPSAVALHKGDTPPTALDKDGLIRVREAFAEAAKRAGRLGIDLVQIH
EEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
AAHGYLLHQFLSPISNQRTDDYGGSLENRMRFPLEVFDAVRAAFPAGRPVSVRVSGTDWV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
EGGWEVEQTIAFAKALEARGCDAIHVSSGGLAAEQKIPIGPSYQVPLARAVKAAVKIPVV
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
AVGLITGYEQAEAIVSTGDADLIALARAILYNPRWPWHAAAYFGAHVKAPPQYLRSQPHQ
EEEHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHCCCHH
FRDLFLS
HHHHHCC
>Mature Secondary Structure 
STPYLFTPFQVGSLALTNRIIIAPMCQYSAVDGVAQDWHLIHLGNLALSGAALLTIEAT
CCCEEECCCCCCCEEHHCCEEEEECHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEE
AVLPEGRISYADIGLWDDVTEAALRRTLDGVRRYSDMPIGMQLAHAGRKASTDLPWKGGA
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCC
KIAADKPNGWQTVAPSAVALHKGDTPPTALDKDGLIRVREAFAEAAKRAGRLGIDLVQIH
EEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
AAHGYLLHQFLSPISNQRTDDYGGSLENRMRFPLEVFDAVRAAFPAGRPVSVRVSGTDWV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
EGGWEVEQTIAFAKALEARGCDAIHVSSGGLAAEQKIPIGPSYQVPLARAVKAAVKIPVV
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
AVGLITGYEQAEAIVSTGDADLIALARAILYNPRWPWHAAAYFGAHVKAPPQYLRSQPHQ
EEEHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHCCCHH
FRDLFLS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA