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The map label for this gene is kdkA

Identifier: 182681827

GI number: 182681827

Start: 1423852

End: 1424601

Strand: Reverse

Name: kdkA

Synonym: XfasM23_1292

Alternate gene names: 182681827

Gene position: 1424601-1423852 (Counterclockwise)

Preceding gene: 182681829

Following gene: 182681814

Centisome position: 56.18

GC content: 53.6

Gene sequence:

>750_bases
ATGGTTGCATTTGACGCCAACGAAATCCTGACGCCATTCTGCGAGGGTCACAGGGAAGGAGCTATTTTGTTCGATTGCCA
GCGTATGCGGCAAGTCGAGTATGGTCTATTTGTGCCTGCTTGGTGGGGGGAGCGAGCCCATCCGATATCTGAGGGAGGAC
GTGGTAGTGCTTGGTTCGTGGAGGCGTCGTTTGGGAATGCGGTATTGCGTCAGTACCGACGTGGCGGAATGATCGCTATG
CTTAATCGTGATCGTTACTTCTGGTGTGGTGGTCACCGTACTCGAAGTGTCCTTGAGTTCCGCTTGATGCGTGAGTTGAT
CTCGCGAGGGTTGCCGGTTCCAACTCCCTTGGCTGCTTGTTACGTGCGGCATGGTGTGCAATATCGAGCAGCGATCTTGA
TGGAGCGACTGGAGGGAGTGTCTTCGCTTGCTATGTGCGTACGTGGGAACAGCAAAGAGATACATTGGGAGCAGATTGGG
CGGATGATTTCGCGCTTTCATCGCGAGGGGCTGGACCATGCGGATCTTAATGCTCACAACATTCTGTTAGACCAAGCTGG
CCAGTGCTGGTTGATTGATTTCGATCGTGGTGCGCTACGTATTCCTGCGACCAAGTGGCGAGAGCACAATTTAGCCCGCT
TACTGCGCTCATTGCTGAAAATACGGGGGGAACGTAGTGTGGATGCAGTGTATAGGGACTTTGAGCGTTTGTGTCGTGCT
TATGACTTGGCTTGGGGTCGGGGGTGTTGA

Upstream 100 bases:

>100_bases
GCACCAGCGGTAACACGTGAGTGATGTCTCCAAGTGCTGATAAGCGTAACAGGCATAGAGAATAGGGTCTTTGCTCCATC
GTATTGTTACACTTGAACGC

Downstream 100 bases:

>100_bases
TGTTTTGTGATATCTGGGTGCACTGCCTCTCACTGTGGAGTTGGGTTACTCGCAGGTACGGATGAACTCGTGTTTGATGC
GTGTGGTCAGGCTCAGTATG

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLRQYRRGGMIAM
LNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIG
RMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAVYRDFERLCRA
YDLAWGRGC

Sequences:

>Translated_249_residues
MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLRQYRRGGMIAM
LNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIG
RMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAVYRDFERLCRA
YDLAWGRGC
>Mature_249_residues
MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLRQYRRGGMIAM
LNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIG
RMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAVYRDFERLCRA
YDLAWGRGC

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDKA_XYLF2 (B2I5R8)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829987.1
- ProteinModelPortal:   B2I5R8
- GeneID:   6202123
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1292
- HOGENOM:   HBG353234
- OMA:   VYHADLN
- ProtClustDB:   PRK01723
- HAMAP:   MF_00521
- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440

Pfam domain/function: PF06293 Kdo; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 28765; Mature: 28765

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: ACT_SITE 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFV
CCEECCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCEEEE
EASFGNAVLRQYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAAC
EECCCHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
YVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIGRMISRFHREGLDHADLNAHN
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCCCCCCHHH
ILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAVYRDFERLCRA
EEEECCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YDLAWGRGC
HHCCCCCCC
>Mature Secondary Structure
MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFV
CCEECCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCEEEE
EASFGNAVLRQYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAAC
EECCCHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
YVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIGRMISRFHREGLDHADLNAHN
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCCCCCCHHH
ILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAVYRDFERLCRA
EEEECCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YDLAWGRGC
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA