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The map label for this gene is dhmA [H]

Identifier: 182681434

GI number: 182681434

Start: 1046307

End: 1047212

Strand: Direct

Name: dhmA [H]

Synonym: XfasM23_0885

Alternate gene names: 182681434

Gene position: 1046307-1047212 (Clockwise)

Preceding gene: 182681433

Following gene: 182681436

Centisome position: 41.26

GC content: 54.64

Gene sequence:

>906_bases
ATGAGCTATCACGATTACCCCTTTCTCTCGCAGTGTTTTGAGGTCCGTCCGGGAATCAGGATGCGTTATCTGGACGAAGG
TCCGCGTGACGCAGCGGTGGTGGTCATGCTGCATGGCAATCCTTCGTGGAGTTATTACTGGCGTCACTTGGTGGCAGCGT
TGCGTGATGGGTATCGTTGTATCGTTCCGGATCACATTGGTATGGGGCTGTCAGATAAGCCGGGGGACGCGCCGGGTGTG
GTGCCACGTTACGATTACACGTTGCAATCTCGCGTGGATGATTTGGATGCGTTGTTGCGTCATGTGGGTATTGACGATGT
CACGCCGTTGACGCTGGCAGTACACGATTGGGGGGGCATGATCGGGTTTGGCTGGGCGTTGGCGCATGCTGTGCAAGTGC
GGCGCTTGGTGATTACCAACACGGCAGTATTTCCGATGCCGATGTCTAAGAAGATGCCGTGGCAGATTGCCTTGGGGCGT
GATTGGAGGTTTGGTGAATGGATGGTTCGTGGGTTGAATGCTTTTGCACTGGGTGCGGCCTGGTTGGGGGTGGAAACACG
GTTGCCGCGTGCGGTGCGCCGTGCCTATTTGGCACCCTATAACAGTTGGGCCAATCGGATTTCGATCATCCGTTTTATGC
AGGATATTCCGTGTGCTCCAGGTGATCGTGCTTGGCCGTTGTTAGAGGCTACCGGCAAGGCACTGCCCAACTTTGCTGAT
CGTCCTGCGTTCATTGGTTGGGGGATGCAGGATATTGTGTTTGATCATCATTTTTTGGATGAATTCTGCGCTGCTTTGCC
GGGTGCGCAGGTGCAAGTTTTTGATGATGCCGGTCACTATGTTCTGGAAGATAAGAGCAGTGTCCTGGTGCCGGCGATTC
GTGCGTTTCTTGATGCGCACCCATAG

Upstream 100 bases:

>100_bases
TGGGCCGACAGCGCGGTGAGCGGGTGTTCCATCACTTGCGAGTATTAGAGCATCGTCTAGAAACAGACGGCGTTTTCACA
TTGGATCGGTTACGTCACGT

Downstream 100 bases:

>100_bases
TAATAGGTGCAATTGCATGTGTGGCGGATTGTGTTTATTTGCGGGCAATCCTGTCGGTAGTGCTTGTGTGCCGCGCCATG
CAGTGTCGTGATTAAGTAAG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHLVAALRDGYRCIVPDHIGMGLSDKPGDAPGV
VPRYDYTLQSRVDDLDALLRHVGIDDVTPLTLAVHDWGGMIGFGWALAHAVQVRRLVITNTAVFPMPMSKKMPWQIALGR
DWRFGEWMVRGLNAFALGAAWLGVETRLPRAVRRAYLAPYNSWANRISIIRFMQDIPCAPGDRAWPLLEATGKALPNFAD
RPAFIGWGMQDIVFDHHFLDEFCAALPGAQVQVFDDAGHYVLEDKSSVLVPAIRAFLDAHP

Sequences:

>Translated_301_residues
MSYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHLVAALRDGYRCIVPDHIGMGLSDKPGDAPGV
VPRYDYTLQSRVDDLDALLRHVGIDDVTPLTLAVHDWGGMIGFGWALAHAVQVRRLVITNTAVFPMPMSKKMPWQIALGR
DWRFGEWMVRGLNAFALGAAWLGVETRLPRAVRRAYLAPYNSWANRISIIRFMQDIPCAPGDRAWPLLEATGKALPNFAD
RPAFIGWGMQDIVFDHHFLDEFCAALPGAQVQVFDDAGHYVLEDKSSVLVPAIRAFLDAHP
>Mature_300_residues
SYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHLVAALRDGYRCIVPDHIGMGLSDKPGDAPGVV
PRYDYTLQSRVDDLDALLRHVGIDDVTPLTLAVHDWGGMIGFGWALAHAVQVRRLVITNTAVFPMPMSKKMPWQIALGRD
WRFGEWMVRGLNAFALGAAWLGVETRLPRAVRRAYLAPYNSWANRISIIRFMQDIPCAPGDRAWPLLEATGKALPNFADR
PAFIGWGMQDIVFDHHFLDEFCAALPGAQVQVFDDAGHYVLEDKSSVLVPAIRAFLDAHP

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes mono- and di- chlorinated

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=130, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562298, Length=296, Percent_Identity=26.0135135135135, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17554012, Length=297, Percent_Identity=20.5387205387205, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33914; Mature: 33783

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHLVAALRDGYRC
CCCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEE
IVPDHIGMGLSDKPGDAPGVVPRYDYTLQSRVDDLDALLRHVGIDDVTPLTLAVHDWGGM
EECHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCH
IGFGWALAHAVQVRRLVITNTAVFPMPMSKKMPWQIALGRDWRFGEWMVRGLNAFALGAA
HHHHHHHHHHHHHHHHHEECCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
WLGVETRLPRAVRRAYLAPYNSWANRISIIRFMQDIPCAPGDRAWPLLEATGKALPNFAD
HHCHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
RPAFIGWGMQDIVFDHHFLDEFCAALPGAQVQVFDDAGHYVLEDKSSVLVPAIRAFLDAH
CCCEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCC
P
C
>Mature Secondary Structure 
SYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHLVAALRDGYRC
CCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEE
IVPDHIGMGLSDKPGDAPGVVPRYDYTLQSRVDDLDALLRHVGIDDVTPLTLAVHDWGGM
EECHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCH
IGFGWALAHAVQVRRLVITNTAVFPMPMSKKMPWQIALGRDWRFGEWMVRGLNAFALGAA
HHHHHHHHHHHHHHHHHEECCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
WLGVETRLPRAVRRAYLAPYNSWANRISIIRFMQDIPCAPGDRAWPLLEATGKALPNFAD
HHCHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
RPAFIGWGMQDIVFDHHFLDEFCAALPGAQVQVFDDAGHYVLEDKSSVLVPAIRAFLDAH
CCCEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12147465 [H]