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The map label for this gene is ptrB [H]

Identifier: 182681287

GI number: 182681287

Start: 861786

End: 864005

Strand: Direct

Name: ptrB [H]

Synonym: XfasM23_0732

Alternate gene names: 182681287

Gene position: 861786-864005 (Clockwise)

Preceding gene: 182681286

Following gene: 182681288

Centisome position: 33.99

GC content: 50.68

Gene sequence:

>2220_bases
ATGGAACTAGAGTGTCTCGACTGTTTCCCCTTGCGTGAAAGGCTGAAATCCATTGAAACTTCAGCTATGACGATCAAACT
TCCCTTCTTATTTTTCGGCCTGATGAACGTGACTACTGCTGTTGTAAGTGCTCCTCTCCCTCCTGATATCGCTAAGCATG
CCCATGCGATCAAAGCGCCGTTTGGCGCAATCCGCAATGATAATTATTACTGGTTACGTGATGACACGCGTACGAACAAG
GTGGTGTTGAGTTATTTGAACGCTGAAAATGCGTATGCCGACAAGGTGTTGGAACCACTCAAGCCGTTACAGCAGACCTT
GTATAAGGAGATTGTTGCTCGCATCAAGAAGGATGATGCCAGTGTTCCGTACCGGAAACACGGTTGGTTTTACTATTCCA
GGTTTGAATCCGGTAAGGATTATCCGATTCATGCGCGTCGCAAAGATGGTTCTGGGCTTGATGCTGCCGTGATTCTGGCG
GCGAATGCGTCCGGTGACTTTGCTGGTGAACAAGTATTACTGGACGTTAACGCGTTGGCTGCAGGTAAGAGTTACTTCAG
TGTGGCTCATGCTGAGGTGAGTCCTAATACTCATCTGTTGGCTTGGGCCGAGGACGGTGTGGGTCGACGTCAGTATACGG
TTCGCTTCAAAAATCTGGAGACTGGGGTGCTTTATCAGGATGAAATCCATGGTGCGTCGTCTAGCGTGGTTTGGGCTGAC
GATAATAAGACGTTGTTCTACATTGAGAATGATCCTAAAACGCTGCTGACTAAGCGTGTTAAAAAGCATGTGCTTGGTAC
CCCTGTCAGTACCGATGTGGTGGTTTATGAGGAGCACGACGATAGTTTCTATATGGACATCGAACGTACGCGTGATGAGA
AATACATTGTGGTTTCTATGGAAAGCACGGTTTCTTCCGAAATGCGTTATGCACCTGCGGATCTGTCGAAGGGGTTTGTC
GTGTTGGCTCGGCGTGAGCGCGACGTGAAATATGGGGGAGATCATTTTGACAGTCGTTGGGTGATCCGCACGAATGCCGA
CGGTGCCAAAAATTACAAGTTGGTCACTGCACCCAGTGATGCGACTTTGCGTAGTCAGTGGCGTGACTTGGTCGTGCACG
ATCCAGCAGTCTTTATTGAGGATTTTGAGCTGTTCGACGGTTTTACTGCGATCCAAGAGCGTTCTCAGGGCTTGGAGCGG
GTGCGTCTGCTCAAGGCTGATGGCCAACACACTGATGTTGCTGCGGATGAGCCGGCGTACTCAATGGGTCTTTCTGAGAA
TCCCGAGCCGGACAATCCGTGGCTGCGTTATACCTATACTTCGTTAACGACTCCGGCGACGACTTATGAGTTCAACGTGC
GTACTGGTGAGCGTCGTCAACTCAAGCAGCAGCCTGTGATTGGTTACGATCCGTCGCAGTACGTCACGGAGCGTCTGTGG
GTGACTGCGCGGGATGGTGTGAAGGTGCCAGTGTCGCTGGTGTATCGCAAAGGTTTTAAGAAAGACGGCACTGCTGCGCT
GTATCAGTACGCGTATGGCAGTTACGGTTTGTCCACAGATCCAGGGTTTAATTTGCCAGTGGTCAGCTTGCTTGATCGTG
GTGTTGTCTACGCGATTGCGCACATCCGTGGTGGTCAGGAGATGGGCCGGCAGTGGTATGACGATGGTAAGTTGCTGCAT
AAGCAGAATACGTTTAATGATTTTATTGATGTGACGCGGGAATTGGTTGCGCAGGGATATGCCGCCAAGGGACGTGTGGC
CGCGGCCGGTGGTAGTGCCGGTGGTTTGTTGATGGGTGTGGTGGCTAATCAGGCGCCGAGTGATTACCGTGTGATCGTGG
CGCAGGTGCCATTTGTTGATGTAGTGACGACGATGTTGGACCCGAGTATTCCGTTGACCACCAATGAGTACGATGAGTGG
GGTAATCCTGAGCAGAAGACTTATTACGATTACATGTTGACGTATTCGCCTTACGACAACGTGGTGCATCAGGCTTATCC
AGCGTTGTTTGTTGGCACGGGGTTATGGGATTCACAGGTGCAGTATTGGGAGCCGGCTAAATGGGTGGCTAAGCTGCGTG
ATGAGAATACGGGGACTTTTCCGATTGTATTCAGAGTCAATATGGATGCCGGTCATGGTGGGAAGTCTGGGCGTTTCAGG
CGTTACCAGGAATTGGCTGAGTCCTATGCTTTCGTACTTCACCATCTTGAAGTGAAGTGA

Upstream 100 bases:

>100_bases
ATTTTAATTCGGAAAAGTGTGTTTATTAAGAGCGGTGAAGAGCGAGGCCGTTGCAGTGTGCAATGTGGTTCCGGTTCGTT
ATCGGAACGAGGATCGTTTA

Downstream 100 bases:

>100_bases
AGTGAAGTGAAGTGGGAGGACGTTGTTGCATGTTGTGATGCTTGGCGTCTTTCTTCATTGTATGCTCGTCGGGTTGCGCT
TGGTTTCCGTAGATATACTT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MELECLDCFPLRERLKSIETSAMTIKLPFLFFGLMNVTTAVVSAPLPPDIAKHAHAIKAPFGAIRNDNYYWLRDDTRTNK
VVLSYLNAENAYADKVLEPLKPLQQTLYKEIVARIKKDDASVPYRKHGWFYYSRFESGKDYPIHARRKDGSGLDAAVILA
ANASGDFAGEQVLLDVNALAAGKSYFSVAHAEVSPNTHLLAWAEDGVGRRQYTVRFKNLETGVLYQDEIHGASSSVVWAD
DNKTLFYIENDPKTLLTKRVKKHVLGTPVSTDVVVYEEHDDSFYMDIERTRDEKYIVVSMESTVSSEMRYAPADLSKGFV
VLARRERDVKYGGDHFDSRWVIRTNADGAKNYKLVTAPSDATLRSQWRDLVVHDPAVFIEDFELFDGFTAIQERSQGLER
VRLLKADGQHTDVAADEPAYSMGLSENPEPDNPWLRYTYTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLW
VTARDGVKVPVSLVYRKGFKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLH
KQNTFNDFIDVTRELVAQGYAAKGRVAAAGGSAGGLLMGVVANQAPSDYRVIVAQVPFVDVVTTMLDPSIPLTTNEYDEW
GNPEQKTYYDYMLTYSPYDNVVHQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDENTGTFPIVFRVNMDAGHGGKSGRFR
RYQELAESYAFVLHHLEVK

Sequences:

>Translated_739_residues
MELECLDCFPLRERLKSIETSAMTIKLPFLFFGLMNVTTAVVSAPLPPDIAKHAHAIKAPFGAIRNDNYYWLRDDTRTNK
VVLSYLNAENAYADKVLEPLKPLQQTLYKEIVARIKKDDASVPYRKHGWFYYSRFESGKDYPIHARRKDGSGLDAAVILA
ANASGDFAGEQVLLDVNALAAGKSYFSVAHAEVSPNTHLLAWAEDGVGRRQYTVRFKNLETGVLYQDEIHGASSSVVWAD
DNKTLFYIENDPKTLLTKRVKKHVLGTPVSTDVVVYEEHDDSFYMDIERTRDEKYIVVSMESTVSSEMRYAPADLSKGFV
VLARRERDVKYGGDHFDSRWVIRTNADGAKNYKLVTAPSDATLRSQWRDLVVHDPAVFIEDFELFDGFTAIQERSQGLER
VRLLKADGQHTDVAADEPAYSMGLSENPEPDNPWLRYTYTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLW
VTARDGVKVPVSLVYRKGFKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLH
KQNTFNDFIDVTRELVAQGYAAKGRVAAAGGSAGGLLMGVVANQAPSDYRVIVAQVPFVDVVTTMLDPSIPLTTNEYDEW
GNPEQKTYYDYMLTYSPYDNVVHQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDENTGTFPIVFRVNMDAGHGGKSGRFR
RYQELAESYAFVLHHLEVK
>Mature_739_residues
MELECLDCFPLRERLKSIETSAMTIKLPFLFFGLMNVTTAVVSAPLPPDIAKHAHAIKAPFGAIRNDNYYWLRDDTRTNK
VVLSYLNAENAYADKVLEPLKPLQQTLYKEIVARIKKDDASVPYRKHGWFYYSRFESGKDYPIHARRKDGSGLDAAVILA
ANASGDFAGEQVLLDVNALAAGKSYFSVAHAEVSPNTHLLAWAEDGVGRRQYTVRFKNLETGVLYQDEIHGASSSVVWAD
DNKTLFYIENDPKTLLTKRVKKHVLGTPVSTDVVVYEEHDDSFYMDIERTRDEKYIVVSMESTVSSEMRYAPADLSKGFV
VLARRERDVKYGGDHFDSRWVIRTNADGAKNYKLVTAPSDATLRSQWRDLVVHDPAVFIEDFELFDGFTAIQERSQGLER
VRLLKADGQHTDVAADEPAYSMGLSENPEPDNPWLRYTYTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLW
VTARDGVKVPVSLVYRKGFKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLH
KQNTFNDFIDVTRELVAQGYAAKGRVAAAGGSAGGLLMGVVANQAPSDYRVIVAQVPFVDVVTTMLDPSIPLTTNEYDEW
GNPEQKTYYDYMLTYSPYDNVVHQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDENTGTFPIVFRVNMDAGHGGKSGRFR
RYQELAESYAFVLHHLEVK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=732, Percent_Identity=24.8633879781421, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI284172420, Length=427, Percent_Identity=25.5269320843091, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI284172413, Length=427, Percent_Identity=25.5269320843091, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI70778815, Length=427, Percent_Identity=25.5269320843091, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI284172438, Length=427, Percent_Identity=25.5269320843091, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI284172431, Length=427, Percent_Identity=25.5269320843091, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI108860686, Length=218, Percent_Identity=32.1100917431193, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI108860692, Length=214, Percent_Identity=31.7757009345794, Blast_Score=120, Evalue=6e-27,
Organism=Escherichia coli, GI1788150, Length=689, Percent_Identity=44.9927431059507, Blast_Score=600, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24583414, Length=744, Percent_Identity=22.7150537634409, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI221510989, Length=717, Percent_Identity=22.8730822873082, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 83378; Mature: 83378

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELECLDCFPLRERLKSIETSAMTIKLPFLFFGLMNVTTAVVSAPLPPDIAKHAHAIKAP
CCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
FGAIRNDNYYWLRDDTRTNKVVLSYLNAENAYADKVLEPLKPLQQTLYKEIVARIKKDDA
CCCEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVPYRKHGWFYYSRFESGKDYPIHARRKDGSGLDAAVILAANASGDFAGEQVLLDVNALA
CCCCHHCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEHHHH
AGKSYFSVAHAEVSPNTHLLAWAEDGVGRRQYTVRFKNLETGVLYQDEIHGASSSVVWAD
CCCHHHEEEEEEECCCCEEEEECCCCCCCEEEEEEEECCCCCEEEEHHCCCCCCEEEEEC
DNKTLFYIENDPKTLLTKRVKKHVLGTPVSTDVVVYEEHDDSFYMDIERTRDEKYIVVSM
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEEE
ESTVSSEMRYAPADLSKGFVVLARRERDVKYGGDHFDSRWVIRTNADGAKNYKLVTAPSD
CCHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCC
ATLRSQWRDLVVHDPAVFIEDFELFDGFTAIQERSQGLERVRLLKADGQHTDVAADEPAY
CHHHHHHHHEEEECCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SMGLSENPEPDNPWLRYTYTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLW
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHEE
VTARDGVKVPVSLVYRKGFKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIA
EEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEE
HIRGGQEMGRQWYDDGKLLHKQNTFNDFIDVTRELVAQGYAAKGRVAAAGGSAGGLLMGV
HHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEE
VANQAPSDYRVIVAQVPFVDVVTTMLDPSIPLTTNEYDEWGNPEQKTYYDYMLTYSPYDN
ECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHH
VVHQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDENTGTFPIVFRVNMDAGHGGKSGRFR
HHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHH
RYQELAESYAFVLHHLEVK
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELECLDCFPLRERLKSIETSAMTIKLPFLFFGLMNVTTAVVSAPLPPDIAKHAHAIKAP
CCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
FGAIRNDNYYWLRDDTRTNKVVLSYLNAENAYADKVLEPLKPLQQTLYKEIVARIKKDDA
CCCEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVPYRKHGWFYYSRFESGKDYPIHARRKDGSGLDAAVILAANASGDFAGEQVLLDVNALA
CCCCHHCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEHHHH
AGKSYFSVAHAEVSPNTHLLAWAEDGVGRRQYTVRFKNLETGVLYQDEIHGASSSVVWAD
CCCHHHEEEEEEECCCCEEEEECCCCCCCEEEEEEEECCCCCEEEEHHCCCCCCEEEEEC
DNKTLFYIENDPKTLLTKRVKKHVLGTPVSTDVVVYEEHDDSFYMDIERTRDEKYIVVSM
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEEE
ESTVSSEMRYAPADLSKGFVVLARRERDVKYGGDHFDSRWVIRTNADGAKNYKLVTAPSD
CCHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCC
ATLRSQWRDLVVHDPAVFIEDFELFDGFTAIQERSQGLERVRLLKADGQHTDVAADEPAY
CHHHHHHHHEEEECCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SMGLSENPEPDNPWLRYTYTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLW
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHEE
VTARDGVKVPVSLVYRKGFKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIA
EEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEE
HIRGGQEMGRQWYDDGKLLHKQNTFNDFIDVTRELVAQGYAAKGRVAAAGGSAGGLLMGV
HHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEE
VANQAPSDYRVIVAQVPFVDVVTTMLDPSIPLTTNEYDEWGNPEQKTYYDYMLTYSPYDN
ECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHH
VVHQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDENTGTFPIVFRVNMDAGHGGKSGRFR
HHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHH
RYQELAESYAFVLHHLEVK
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]