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The map label for this gene is pyrH [H]

Identifier: 197294562

GI number: 197294562

Start: 510210

End: 510926

Strand: Reverse

Name: pyrH [H]

Synonym: PAa_0517

Alternate gene names: 197294562

Gene position: 510926-510210 (Counterclockwise)

Preceding gene: 197294563

Following gene: 197294561

Centisome position: 58.06

GC content: 34.31

Gene sequence:

>717_bases
ATGTATAAAAAAATTCTTTTAAAATTAAGCGGTGAGTCTCTTAAAGGAAATATTCCTTACGGAATAGATCCTATCACCAT
TAAAAAAATCGCTTTAGAAATTAAAGAAATTAAAGATTTAGGAATTGAAATTGCAATCATTGTGGGAGCAGGAAATCTTT
GGCGTGGCCTAATTGGTGAAGAACTTGGTATGGACCGGTCTCAAGCTGATTACATGGGGATGTTAGGAACTATCATGAAT
TCTTTAGCGCTTCAAGATGCTTTAGAACAAACAAACACCGTCACTCGCGTTATGACAGCTTTTCCTGTTGCTACAGTAGC
AGAACCTTATATTCGCAGAAAAGCTATGCATCATCTAGAAAAAGGTAGAGTAGTTATTTTGGGTGCTGGTTCTGGTTCGC
CATATTTTTCAACTGATACCGCTGCCGCTCAAAGAGCAGCTGAATTAAACATCGATGTCATTTTGATGGCTAAAAATAAC
ATTGAAGGGGTTTATGATAAAGATCCTAAAAAATATGACAACGCTGTTTTAATCAAAAAAATGAAACACGAACAGATCTT
ATCAGAAAGACTTTCTGTTATGGATATCACAGCGGCTTCCCTTTGTTTAGAAAACAATATCGATATTTTAGTTTTTAATA
TGCTAAAACCAGGAAACATAAAAAAAGCTGTTTTACAAAAAGAAATTGGTACTATTATTAGCTCAAAAGGAGAATAA

Upstream 100 bases:

>100_bases
AACAATAATACAAATGTTGTTTCTTATTTTCGTTGGTCAATCGCTAATCAATAATTTTCAGTTTTTTGAATAAAAATTAT
TCATGAAAAAAGGTCGTCAA

Downstream 100 bases:

>100_bases
AGGTGGAGCAAAAAGCGCAAGAAACAATTTTATTAATTGAAAAAAAAATGTCTCAAGCACAAGAGGTCATGCTCAAGAAT
TTTTTAGAAATTCGAACGGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MYKKILLKLSGESLKGNIPYGIDPITIKKIALEIKEIKDLGIEIAIIVGAGNLWRGLIGEELGMDRSQADYMGMLGTIMN
SLALQDALEQTNTVTRVMTAFPVATVAEPYIRRKAMHHLEKGRVVILGAGSGSPYFSTDTAAAQRAAELNIDVILMAKNN
IEGVYDKDPKKYDNAVLIKKMKHEQILSERLSVMDITAASLCLENNIDILVFNMLKPGNIKKAVLQKEIGTIISSKGE

Sequences:

>Translated_238_residues
MYKKILLKLSGESLKGNIPYGIDPITIKKIALEIKEIKDLGIEIAIIVGAGNLWRGLIGEELGMDRSQADYMGMLGTIMN
SLALQDALEQTNTVTRVMTAFPVATVAEPYIRRKAMHHLEKGRVVILGAGSGSPYFSTDTAAAQRAAELNIDVILMAKNN
IEGVYDKDPKKYDNAVLIKKMKHEQILSERLSVMDITAASLCLENNIDILVFNMLKPGNIKKAVLQKEIGTIISSKGE
>Mature_238_residues
MYKKILLKLSGESLKGNIPYGIDPITIKKIALEIKEIKDLGIEIAIIVGAGNLWRGLIGEELGMDRSQADYMGMLGTIMN
SLALQDALEQTNTVTRVMTAFPVATVAEPYIRRKAMHHLEKGRVVILGAGSGSPYFSTDTAAAQRAAELNIDVILMAKNN
IEGVYDKDPKKYDNAVLIKKMKHEQILSERLSVMDITAASLCLENNIDILVFNMLKPGNIKKAVLQKEIGTIISSKGE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=234, Percent_Identity=41.8803418803419, Blast_Score=200, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26100; Mature: 26100

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKKILLKLSGESLKGNIPYGIDPITIKKIALEIKEIKDLGIEIAIIVGAGNLWRGLIGE
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHH
ELGMDRSQADYMGMLGTIMNSLALQDALEQTNTVTRVMTAFPVATVAEPYIRRKAMHHLE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRVVILGAGSGSPYFSTDTAAAQRAAELNIDVILMAKNNIEGVYDKDPKKYDNAVLIKK
CCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHCCHHHHHH
MKHEQILSERLSVMDITAASLCLENNIDILVFNMLKPGNIKKAVLQKEIGTIISSKGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYKKILLKLSGESLKGNIPYGIDPITIKKIALEIKEIKDLGIEIAIIVGAGNLWRGLIGE
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHH
ELGMDRSQADYMGMLGTIMNSLALQDALEQTNTVTRVMTAFPVATVAEPYIRRKAMHHLE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRVVILGAGSGSPYFSTDTAAAQRAAELNIDVILMAKNNIEGVYDKDPKKYDNAVLIKK
CCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHCCHHHHHH
MKHEQILSERLSVMDITAASLCLENNIDILVFNMLKPGNIKKAVLQKEIGTIISSKGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA