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The map label for this gene is insK [H]

Identifier: 197294459

GI number: 197294459

Start: 395386

End: 396555

Strand: Direct

Name: insK [H]

Synonym: PAa_0384

Alternate gene names: 197294459

Gene position: 395386-396555 (Clockwise)

Preceding gene: 197294458

Following gene: 197294481

Centisome position: 44.93

GC content: 27.01

Gene sequence:

>1170_bases
ATGAGCTTAGAAATGGAGAAAAAAATAAAATTATATTCTTTGGATGTTAAATTAAAGGCTGTTTTTGCGAAACAAGAAGG
CAAAAGATGTAAAGAAATACAGCAAAATTTTAATATTAAAAATCGGAGTCAGATTTATCAATGGGTGGAGTGGTATGAAT
TAAAAGGCGCAGAAAGGCTAGAACAATCAATTAGAGGAAAAAGAAAGGTTGTTGAAAAAGGAATTAATCCAATTAAAACG
GAAATCAAAAAACAACTTAAAAATAGTTTCAAGAAAAATAGAAAATTATATTTAGATATTATTAATAAATATCAAAAAGA
AGTTTCGTTAAAACAATTGATTAAATGGTTGTCTATTTCAAAAACTAGTTATTTTCGGTGGATTAAACAAAGTCTTCATC
CTAGACCTCAAAGTGAATTGGAAAAAGCCTTGTTTCAAATATGTCAGCAAGGTTCATATATCACAACTGATGGCAAGAGA
AAAAGAAGGCTCGGTTATCGCGTGGTTCATCAAAAACTAATTGACCTTAAATTTAAGATAAACTCTAAGACTGTTTTAAA
GCTAATGCATCAATTTGGGTTATTATCACAAAGAATACAAAGAAAAAATCAATATTATTATGATTTAGCTATTCAAAAAG
AAAATAATTTAAAAAATCTAATTCAAAACAATTATCACGCCACAAGACCGTTTGAAAAATTATGTACTGATATTACTTAT
ATACCTTTTGGAAAAAATAACCAAAAATTATTTGTTTCTGCGATAATGGATTTGTATAACCGTGAAATTATTGGTTACAA
CATTTCTAAAATCGCTGATGTTGATTTTGTAATTAATACTTTAAAAGTTATTCCTGCATTAATAATCCCTTGCATTCTTC
ATTGTGATAGAGCAAGTGTTTATACTTCTAAAAAATATCAAACTGAGTTAAAAGCTAATAATCTAATAACTAGTTTCTCA
GCTAAATCCATGCCAACTGATAATGCTTGCATGGAGGCATTTTGGGCCAACATGAAACGAGAAACTATCCATTATGAAAA
AATGCAAAATCTAGGCGAACATCAAATTATAGAAATTATTCCTGATTACATTGAATATTATAATATTTATCGTAAAATGA
AAGTTCTAAATTATTTATCACCCAAAGAATTTAAAATAAAAAAATATTAA

Upstream 100 bases:

>100_bases
TTTAAAAGATTTTATTGTTGTTTTTTTTATAAAACCCGACAAAACTAGTTTTTTTAACAATAAAGGCTTAAAAAAATAAA
GCTATGTTAACAAAACAGAA

Downstream 100 bases:

>100_bases
TTAATAATTAAAATTATAAGCCCTTCATAACGGAGGGCAATTTGTGTAGGTTTTTTTAAGTTCTTTAAAAAAATAACTTT
TTAAAAAACCATAACACCTC

Product: Putative phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSLEMEKKIKLYSLDVKLKAVFAKQEGKRCKEIQQNFNIKNRSQIYQWVEWYELKGAERLEQSIRGKRKVVEKGINPIKT
EIKKQLKNSFKKNRKLYLDIINKYQKEVSLKQLIKWLSISKTSYFRWIKQSLHPRPQSELEKALFQICQQGSYITTDGKR
KRRLGYRVVHQKLIDLKFKINSKTVLKLMHQFGLLSQRIQRKNQYYYDLAIQKENNLKNLIQNNYHATRPFEKLCTDITY
IPFGKNNQKLFVSAIMDLYNREIIGYNISKIADVDFVINTLKVIPALIIPCILHCDRASVYTSKKYQTELKANNLITSFS
AKSMPTDNACMEAFWANMKRETIHYEKMQNLGEHQIIEIIPDYIEYYNIYRKMKVLNYLSPKEFKIKKY

Sequences:

>Translated_389_residues
MSLEMEKKIKLYSLDVKLKAVFAKQEGKRCKEIQQNFNIKNRSQIYQWVEWYELKGAERLEQSIRGKRKVVEKGINPIKT
EIKKQLKNSFKKNRKLYLDIINKYQKEVSLKQLIKWLSISKTSYFRWIKQSLHPRPQSELEKALFQICQQGSYITTDGKR
KRRLGYRVVHQKLIDLKFKINSKTVLKLMHQFGLLSQRIQRKNQYYYDLAIQKENNLKNLIQNNYHATRPFEKLCTDITY
IPFGKNNQKLFVSAIMDLYNREIIGYNISKIADVDFVINTLKVIPALIIPCILHCDRASVYTSKKYQTELKANNLITSFS
AKSMPTDNACMEAFWANMKRETIHYEKMQNLGEHQIIEIIPDYIEYYNIYRKMKVLNYLSPKEFKIKKY
>Mature_388_residues
SLEMEKKIKLYSLDVKLKAVFAKQEGKRCKEIQQNFNIKNRSQIYQWVEWYELKGAERLEQSIRGKRKVVEKGINPIKTE
IKKQLKNSFKKNRKLYLDIINKYQKEVSLKQLIKWLSISKTSYFRWIKQSLHPRPQSELEKALFQICQQGSYITTDGKRK
RRLGYRVVHQKLIDLKFKINSKTVLKLMHQFGLLSQRIQRKNQYYYDLAIQKENNLKNLIQNNYHATRPFEKLCTDITYI
PFGKNNQKLFVSAIMDLYNREIIGYNISKIADVDFVINTLKVIPALIIPCILHCDRASVYTSKKYQTELKANNLITSFSA
KSMPTDNACMEAFWANMKRETIHYEKMQNLGEHQIIEIIPDYIEYYNIYRKMKVLNYLSPKEFKIKKY

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=266, Percent_Identity=24.4360902255639, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789981, Length=295, Percent_Identity=28.4745762711864, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788405, Length=303, Percent_Identity=27.0627062706271, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787263, Length=303, Percent_Identity=27.0627062706271, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786753, Length=303, Percent_Identity=27.0627062706271, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786570, Length=303, Percent_Identity=27.0627062706271, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786490, Length=303, Percent_Identity=27.0627062706271, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 46421; Mature: 46290

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEMEKKIKLYSLDVKLKAVFAKQEGKRCKEIQQNFNIKNRSQIYQWVEWYELKGAERL
CCCCHHHCEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHH
EQSIRGKRKVVEKGINPIKTEIKKQLKNSFKKNRKLYLDIINKYQKEVSLKQLIKWLSIS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KTSYFRWIKQSLHPRPQSELEKALFQICQQGSYITTDGKRKRRLGYRVVHQKLIDLKFKI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHEEE
NSKTVLKLMHQFGLLSQRIQRKNQYYYDLAIQKENNLKNLIQNNYHATRPFEKLCTDITY
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHHCCCEE
IPFGKNNQKLFVSAIMDLYNREIIGYNISKIADVDFVINTLKVIPALIIPCILHCDRASV
ECCCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YTSKKYQTELKANNLITSFSAKSMPTDNACMEAFWANMKRETIHYEKMQNLGEHQIIEII
HHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
PDYIEYYNIYRKMKVLNYLSPKEFKIKKY
HHHHHHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure 
SLEMEKKIKLYSLDVKLKAVFAKQEGKRCKEIQQNFNIKNRSQIYQWVEWYELKGAERL
CCCHHHCEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHH
EQSIRGKRKVVEKGINPIKTEIKKQLKNSFKKNRKLYLDIINKYQKEVSLKQLIKWLSIS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KTSYFRWIKQSLHPRPQSELEKALFQICQQGSYITTDGKRKRRLGYRVVHQKLIDLKFKI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHEEE
NSKTVLKLMHQFGLLSQRIQRKNQYYYDLAIQKENNLKNLIQNNYHATRPFEKLCTDITY
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHHCCCEE
IPFGKNNQKLFVSAIMDLYNREIIGYNISKIADVDFVINTLKVIPALIIPCILHCDRASV
ECCCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YTSKKYQTELKANNLITSFSAKSMPTDNACMEAFWANMKRETIHYEKMQNLGEHQIIEII
HHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
PDYIEYYNIYRKMKVLNYLSPKEFKIKKY
HHHHHHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]