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The map label for this gene is dnaC [H]

Identifier: 197294350

GI number: 197294350

Start: 265947

End: 267230

Strand: Direct

Name: dnaC [H]

Synonym: PAa_0225

Alternate gene names: 197294350

Gene position: 265947-267230 (Clockwise)

Preceding gene: 197294346

Following gene: 197294351

Centisome position: 30.22

GC content: 30.53

Gene sequence:

>1284_bases
ATGATTGAAGCCGAACGTGCATTATTGGGAGCACTATTATTAAATCCAGAAAAAATGGATGTTGTTATAAATTTAGTCAA
CACAAACAATTTTTCCAACCCCAAGCATCGTTGTATCTTTGAGACAATGAAGCAATTAAAACTGCAAAATCGCGAAATTG
ATTATGTTACGGTGGGTTCCGTTTTAGATAACAATTTATACAAAATAGGAGGAATTGATTATTTAATTGAATTAGTGGAG
ACGTCCCCTGCAAGTGAATATTTAGAAACTTACATTGATTTAATTAAAGAAAATGCCCTTAAAAGAGATTTGTTGGGATT
AATCAAGCAATTACCTACTGAATTATCAAAAAGTAAAAATATCCATAATTATTTGCAAGCAGTCAAAACCCAAGTAGAAA
GTTTTATGCAAAAAACTAAATCTCCTTTCATTTCTACAAAAAAATTAATTCCTTATATTCGCCAAAGTATAGTTAATGAT
GAAAAAGACAACCAACTTGTAGGAATAAAAACAGGTTTCAAAAATCTAGATGAATTAATTTCTGGTTTCAAACCAAAGGA
ATTAATTATCTTAGGAGCAAGAACTGGGATGGGGAAAACTGCTTTTATGTTAAATTTGGCTTGTAATATTGCAAAAAAAT
TTACTACCAACCCCGAAAACCAAAAAGCAGTTATTTTTAGTTTAGAAATGGCAGCAGAAGAATTAGGAATTAGGCTACTT
TCTTCTGCTTCTCAAATCCCTTTAAAACAACTCCAACACAAAAACTTAACTAAAAATGACAAATTACAGTTACTTATCGC
TGATGACAAAATTACGCAATTAAACATTTTAATTGATGATGATAGAAATAACAAAATTGAAGATATTAAAACCAAATGCC
GTCAAATGAAATATACTAAGGGACTTGATATTGTCTTCATTGATTACCTCCATTTATTAAAAGACGACCAAAGTTTTAAT
TCATACCAAGCAATATCTGTGATTTCACGCAAATTAAAAAAACTAGCAAGTGAACTTAATATTCCAATTGTAGCTTTGAG
TCAAATGAACCGTGCAACCTATGTAAGAGAAGTTAAAAGCCCACAATTAACAGATTTAAGAGATTCGGGAACAATCGAAC
AAGACGCTGATGTTGTGATGTTATTACACCGCGAAAGTTATTATCAAAAACCTGATATTGACCCACATACGAATTTAATT
ATTGCCAAAAACCGTAGCGGTCAATTAGGTGAATGTAGTTTTAATTTTTATAAACAAATCCAAAGATTTGAAGCAAAAGA
ATAA

Upstream 100 bases:

>100_bases
GTACTGGTTGAGAACAACAAATTTATCCAAATTGTTTATTAATTAAAAATAAACAGTTTGGATTTTTTTGTATCCAAACT
GAGAAAAAGGAGTTTGAAAG

Downstream 100 bases:

>100_bases
GAATAAAAAAGGAAATAAAAATATGAAACAAATATCTAATTTAGATTTTAATAATATTAACGTTTTTAATCATAAATCTT
TGTGCGTTAACATAACCAAA

Product: Replicative DNA helicase, prophage

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIEAERALLGALLLNPEKMDVVINLVNTNNFSNPKHRCIFETMKQLKLQNREIDYVTVGSVLDNNLYKIGGIDYLIELVE
TSPASEYLETYIDLIKENALKRDLLGLIKQLPTELSKSKNIHNYLQAVKTQVESFMQKTKSPFISTKKLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPKELIILGARTGMGKTAFMLNLACNIAKKFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIEDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
SYQAISVISRKLKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE

Sequences:

>Translated_427_residues
MIEAERALLGALLLNPEKMDVVINLVNTNNFSNPKHRCIFETMKQLKLQNREIDYVTVGSVLDNNLYKIGGIDYLIELVE
TSPASEYLETYIDLIKENALKRDLLGLIKQLPTELSKSKNIHNYLQAVKTQVESFMQKTKSPFISTKKLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPKELIILGARTGMGKTAFMLNLACNIAKKFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIEDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
SYQAISVISRKLKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE
>Mature_427_residues
MIEAERALLGALLLNPEKMDVVINLVNTNNFSNPKHRCIFETMKQLKLQNREIDYVTVGSVLDNNLYKIGGIDYLIELVE
TSPASEYLETYIDLIKENALKRDLLGLIKQLPTELSKSKNIHNYLQAVKTQVESFMQKTKSPFISTKKLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPKELIILGARTGMGKTAFMLNLACNIAKKFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIEDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
SYQAISVISRKLKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=440, Percent_Identity=31.5909090909091, Blast_Score=218, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48759; Mature: 48759

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAERALLGALLLNPEKMDVVINLVNTNNFSNPKHRCIFETMKQLKLQNREIDYVTVGS
CCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECH
VLDNNLYKIGGIDYLIELVETSPASEYLETYIDLIKENALKRDLLGLIKQLPTELSKSKN
HHCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IHNYLQAVKTQVESFMQKTKSPFISTKKLIPYIRQSIVNDEKDNQLVGIKTGFKNLDELI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
SGFKPKELIILGARTGMGKTAFMLNLACNIAKKFTTNPENQKAVIFSLEMAAEELGIRLL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHH
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIEDIKTKCRQMKYTK
HCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
GLDIVFIDYLHLLKDDQSFNSYQAISVISRKLKKLASELNIPIVALSQMNRATYVREVKS
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHCHHHHHHHHHCC
PQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLIIAKNRSGQLGECSFNFYKQI
CCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
QRFEAKE
HHHHCCC
>Mature Secondary Structure
MIEAERALLGALLLNPEKMDVVINLVNTNNFSNPKHRCIFETMKQLKLQNREIDYVTVGS
CCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECH
VLDNNLYKIGGIDYLIELVETSPASEYLETYIDLIKENALKRDLLGLIKQLPTELSKSKN
HHCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IHNYLQAVKTQVESFMQKTKSPFISTKKLIPYIRQSIVNDEKDNQLVGIKTGFKNLDELI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
SGFKPKELIILGARTGMGKTAFMLNLACNIAKKFTTNPENQKAVIFSLEMAAEELGIRLL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHH
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIEDIKTKCRQMKYTK
HCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
GLDIVFIDYLHLLKDDQSFNSYQAISVISRKLKKLASELNIPIVALSQMNRATYVREVKS
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHCHHHHHHHHHCC
PQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLIIAKNRSGQLGECSFNFYKQI
CCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
QRFEAKE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]