| Definition | Candidatus Phytoplasma australiense, complete genome. |
|---|---|
| Accession | NC_010544 |
| Length | 879,959 |
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The map label for this gene is gyrA [H]
Identifier: 197294339
GI number: 197294339
Start: 252125
End: 254584
Strand: Direct
Name: gyrA [H]
Synonym: PAa_0214
Alternate gene names: 197294339
Gene position: 252125-254584 (Clockwise)
Preceding gene: 197294338
Following gene: 197294340
Centisome position: 28.65
GC content: 30.61
Gene sequence:
>2460_bases ATGATTAACCAAAATCCTAATTTGAATCAAGGAAAGATTAAAGAAGTTAATTTAAGCGCAGAAATGCGAAAATCTTTTTT AAGTTATGCAATGAGCGTGATTGTTGCTCGCGCTTTGCCAGATATCCAAGATGGATTAAAGCCGGTCCAAAGACGTATTT TATACGGAATGAAAGAATTGTCTGTTTATAGTAATTCTAGTTATAAAAAAGCTGCTCGTATTGTCGGTGATGTGATGGGG AAATACCATCCCCATGGTGACTCTAGTATTTACGAAGCGATGGTAAGAATGTCACAAGATTTTAGCTATCGTTATCCTTT AGTTGACGGACATGGTAATTTTGGCTCCATTGATGGCCACAAAGCAGCGGCTATGCGTTACACAGAAGTTAAAATGGCCA AAATCGCAATGGAATTAATTAAAAACATTGACAAAGAAACTATTGAATTTGTAGATAATTATGACGGAAGTGAAAAAGAA CCTTTGGTTTTACCAACAGCGATTCCTAATTTATTAATTAACGGTGCTACCGGTATTGCTGTTGGGATGGCGACAAAAAT CCCTACTCATAATTTAGCTGAAGTGGTTGATGGTTTAATTGCTTATATCAAAGATAAAAATATTTCTATTCTTGGATTGA TGCAATATATTAAAGGTCCTGATTTTCCTACTGGAGGCGAACTTTTAGGTTTGAAAGGACTTGAAAACGCCTACAAAACC GGTCAAGGATCGGTTATTATAAAAGCCAAAACTCATATTTTAGAAGAAAAGGGAAAAACTTTAATTGTTGTTACAGAAAT CCCTTATCAAATTAAAAAAAGTGCTTTAATTGAAAAAATTGCGTTTTTAGTAAAAGATAAAGTTATCGAAGGAATTACAG ACCTTAGAGATGAATCCAGTCGCCAAGGGATGAAAATAGTTATTGAATTAAAAAAAAATGCCAATTCCAAAGTCATTTTA AACCAATTATATAAACATTCTCCATTAAGAATTTCTTTTGGTATTAATATGGTTGCTTTGGTTGACAAAAAACCGCAATT AGTTTCTTTAAAAACAATTTTGGAAGCTTTTTTTAATTTTCGTATTCAAGTCATCAACAAACAAAAATTTTTTGAACTCA AAAAAGCTCAAGCAAGAAAACATTTAGTTTTTGCTTTTTTAACTATTTTAAAAGATATTCAAAATGCTATTAAATTAATT AAAAACTCTTCGGATACTAAAGATGCTCAGCAAAAATTAATGGATCAATATCAATTTGATGCAATCCAAAGTAAAGCCAT TTTAGAAATGAGTTTACAAAGATTATCTAACCAAGAAACTCAAAAATTATTTATTGAAGAACAAAAACTAACAAAAGAAA TCGCAGAATGCCAAAGCATTATTGAGTCTCAACCAAAGAAAGAAAAAATATTAGAAAAAGAACTTTTAGAAATTAAAAAG AAATATCAAGATGAAAGAAGAACTGTTCTTAATTTTGATGCTGCTTTAGATGACAAAGATGAAGATTTAATTGAACAAAA AGAAATTATTATCACAATCACTAATAAAGGCTATATTAAAGTTACGGATGCAGAATTTTACCGTCAACAAAAAAGAGGCG GCAAAGGCGCTGCTGGTATGAAAATTTATGAAGAGGATTTCATCGAACATTTGTTATTCACTTCTACTCATAATTTTCTT TTGTTTTTCACTAATAAAGGTAGAGTTTATCAATTAAAAGGATATCAAATTAATTTAAGCGATAAAAGCTCTAAAGGGAT CCCTTTAGTTAATTTATTAAATTTGAAACCAGGCGAAACTTTAACTTCTTGCGCTAGTGTCAAAAATTTTGATCAACCCG ATAATTATTTATTTTTTGCTACTAAAAAAGGCATAGTTAAAAAAACTTCTTTAAAAGAATACTCTAATATTCGCGAAAAT GGCAAAATTGCCATTGTTTTAAGAGATGATGATGAAGTATTAACGGTTGCAAACACCAATGGACGTCAAAATATTATTTT GGCTTCCAATAACGGTAATGCTATTTGTTTTGATGAATCCCAAACTAGAAAAACTAGCCGACAAAGTCAAGGCGTTATCG GAATGGATTTAAAGAAAGGCGAATTTTTAATTGGTGCTGCTTTGTTTGACCCCAATTCCAAAGATCAAAGTATTTTAGTA ATGACTGAAAAAGGCTATGGAAAAATTACAAGTGTCAATCAATATCGCATTCAATCCCGCAATGGCAAAGGTTCAAAAAC AATTAAAATTAATAGTAAAACAGGAAGACTAATTGCTTTAAAAACTGCCGCTTCTTCACAAGATTTAATTATTTCTTCTG ATAAAGGACAAGTGATAAGAGTGTCTATTTCTGATATCAAAAACACTAAACATAAAGCAACTCAAGGAACTAAAATTATA AAGTTAAAAACCGGTCATAAAGCTGTTTTAGTTGCAGTTGAGTCAAAAATTAATGATTAA
Upstream 100 bases:
>100_bases AGAAAAGAATTCATTTTAAATAATGCTTTAGAAGCGGATTTAGATGTTTAAAAACTATAAAAACAACCAGCTAATTAAAT AAAGTAAAGAGGCAAAAAAC
Downstream 100 bases:
>100_bases TCCCAAAAATCCCTCTTTGTCAAAAACAATTTCTTTAACTAAAATAACTAATTCTTCAGCTCAAACTCAAAAATTAGGTT TTTGGTTGGGAAATCAATTA
Product: DNA gyrase alpha subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 819; Mature: 819
Protein sequence:
>819_residues MINQNPNLNQGKIKEVNLSAEMRKSFLSYAMSVIVARALPDIQDGLKPVQRRILYGMKELSVYSNSSYKKAARIVGDVMG KYHPHGDSSIYEAMVRMSQDFSYRYPLVDGHGNFGSIDGHKAAAMRYTEVKMAKIAMELIKNIDKETIEFVDNYDGSEKE PLVLPTAIPNLLINGATGIAVGMATKIPTHNLAEVVDGLIAYIKDKNISILGLMQYIKGPDFPTGGELLGLKGLENAYKT GQGSVIIKAKTHILEEKGKTLIVVTEIPYQIKKSALIEKIAFLVKDKVIEGITDLRDESSRQGMKIVIELKKNANSKVIL NQLYKHSPLRISFGINMVALVDKKPQLVSLKTILEAFFNFRIQVINKQKFFELKKAQARKHLVFAFLTILKDIQNAIKLI KNSSDTKDAQQKLMDQYQFDAIQSKAILEMSLQRLSNQETQKLFIEEQKLTKEIAECQSIIESQPKKEKILEKELLEIKK KYQDERRTVLNFDAALDDKDEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGGKGAAGMKIYEEDFIEHLLFTSTHNFL LFFTNKGRVYQLKGYQINLSDKSSKGIPLVNLLNLKPGETLTSCASVKNFDQPDNYLFFATKKGIVKKTSLKEYSNIREN GKIAIVLRDDDEVLTVANTNGRQNIILASNNGNAICFDESQTRKTSRQSQGVIGMDLKKGEFLIGAALFDPNSKDQSILV MTEKGYGKITSVNQYRIQSRNGKGSKTIKINSKTGRLIALKTAASSQDLIISSDKGQVIRVSISDIKNTKHKATQGTKII KLKTGHKAVLVAVESKIND
Sequences:
>Translated_819_residues MINQNPNLNQGKIKEVNLSAEMRKSFLSYAMSVIVARALPDIQDGLKPVQRRILYGMKELSVYSNSSYKKAARIVGDVMG KYHPHGDSSIYEAMVRMSQDFSYRYPLVDGHGNFGSIDGHKAAAMRYTEVKMAKIAMELIKNIDKETIEFVDNYDGSEKE PLVLPTAIPNLLINGATGIAVGMATKIPTHNLAEVVDGLIAYIKDKNISILGLMQYIKGPDFPTGGELLGLKGLENAYKT GQGSVIIKAKTHILEEKGKTLIVVTEIPYQIKKSALIEKIAFLVKDKVIEGITDLRDESSRQGMKIVIELKKNANSKVIL NQLYKHSPLRISFGINMVALVDKKPQLVSLKTILEAFFNFRIQVINKQKFFELKKAQARKHLVFAFLTILKDIQNAIKLI KNSSDTKDAQQKLMDQYQFDAIQSKAILEMSLQRLSNQETQKLFIEEQKLTKEIAECQSIIESQPKKEKILEKELLEIKK KYQDERRTVLNFDAALDDKDEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGGKGAAGMKIYEEDFIEHLLFTSTHNFL LFFTNKGRVYQLKGYQINLSDKSSKGIPLVNLLNLKPGETLTSCASVKNFDQPDNYLFFATKKGIVKKTSLKEYSNIREN GKIAIVLRDDDEVLTVANTNGRQNIILASNNGNAICFDESQTRKTSRQSQGVIGMDLKKGEFLIGAALFDPNSKDQSILV MTEKGYGKITSVNQYRIQSRNGKGSKTIKINSKTGRLIALKTAASSQDLIISSDKGQVIRVSISDIKNTKHKATQGTKII KLKTGHKAVLVAVESKIND >Mature_819_residues MINQNPNLNQGKIKEVNLSAEMRKSFLSYAMSVIVARALPDIQDGLKPVQRRILYGMKELSVYSNSSYKKAARIVGDVMG KYHPHGDSSIYEAMVRMSQDFSYRYPLVDGHGNFGSIDGHKAAAMRYTEVKMAKIAMELIKNIDKETIEFVDNYDGSEKE PLVLPTAIPNLLINGATGIAVGMATKIPTHNLAEVVDGLIAYIKDKNISILGLMQYIKGPDFPTGGELLGLKGLENAYKT GQGSVIIKAKTHILEEKGKTLIVVTEIPYQIKKSALIEKIAFLVKDKVIEGITDLRDESSRQGMKIVIELKKNANSKVIL NQLYKHSPLRISFGINMVALVDKKPQLVSLKTILEAFFNFRIQVINKQKFFELKKAQARKHLVFAFLTILKDIQNAIKLI KNSSDTKDAQQKLMDQYQFDAIQSKAILEMSLQRLSNQETQKLFIEEQKLTKEIAECQSIIESQPKKEKILEKELLEIKK KYQDERRTVLNFDAALDDKDEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGGKGAAGMKIYEEDFIEHLLFTSTHNFL LFFTNKGRVYQLKGYQINLSDKSSKGIPLVNLLNLKPGETLTSCASVKNFDQPDNYLFFATKKGIVKKTSLKEYSNIREN GKIAIVLRDDDEVLTVANTNGRQNIILASNNGNAICFDESQTRKTSRQSQGVIGMDLKKGEFLIGAALFDPNSKDQSILV MTEKGYGKITSVNQYRIQSRNGKGSKTIKINSKTGRLIALKTAASSQDLIISSDKGQVIRVSISDIKNTKHKATQGTKII KLKTGHKAVLVAVESKIND
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=424, Percent_Identity=25.9433962264151, Blast_Score=90, Evalue=9e-18, Organism=Homo sapiens, GI19913406, Length=355, Percent_Identity=26.4788732394366, Blast_Score=89, Evalue=2e-17, Organism=Escherichia coli, GI1788562, Length=826, Percent_Identity=43.4624697336562, Blast_Score=697, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=675, Percent_Identity=33.7777777777778, Blast_Score=372, Evalue=1e-104, Organism=Caenorhabditis elegans, GI212645845, Length=500, Percent_Identity=26, Blast_Score=91, Evalue=3e-18, Organism=Caenorhabditis elegans, GI212645657, Length=320, Percent_Identity=26.5625, Blast_Score=79, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17535065, Length=291, Percent_Identity=26.8041237113402, Blast_Score=75, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=369, Percent_Identity=24.390243902439, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI17136538, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=1e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR010235 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV; PF08780 NTase_sub_bind [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 91843; Mature: 91843
Theoretical pI: Translated: 10.08; Mature: 10.08
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MINQNPNLNQGKIKEVNLSAEMRKSFLSYAMSVIVARALPDIQDGLKPVQRRILYGMKEL CCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH SVYSNSSYKKAARIVGDVMGKYHPHGDSSIYEAMVRMSQDFSYRYPLVDGHGNFGSIDGH HEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCEEECCCCCCCCCCC KAAAMRYTEVKMAKIAMELIKNIDKETIEFVDNYDGSEKEPLVLPTAIPNLLINGATGIA HHHHEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCHHEECCCCCEE VGMATKIPTHNLAEVVDGLIAYIKDKNISILGLMQYIKGPDFPTGGELLGLKGLENAYKT EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCHHHHHC GQGSVIIKAKTHILEEKGKTLIVVTEIPYQIKKSALIEKIAFLVKDKVIEGITDLRDESS CCCCEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC RQGMKIVIELKKNANSKVILNQLYKHSPLRISFGINMVALVDKKPQLVSLKTILEAFFNF CCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCEEEEEECCCCCEEHHHHHHHHHHCC RIQVINKQKFFELKKAQARKHLVFAFLTILKDIQNAIKLIKNSSDTKDAQQKLMDQYQFD EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH AIQSKAILEMSLQRLSNQETQKLFIEEQKLTKEIAECQSIIESQPKKEKILEKELLEIKK HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH KYQDERRTVLNFDAALDDKDEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGGKGAAGM HHHHHHCEEEEECCCCCCCCHHHHCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCCCCC KIYEEDFIEHLLFTSTHNFLLFFTNKGRVYQLKGYQINLSDKSSKGIPLVNLLNLKPGET EEHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECEEEEECCCCCCCCCEEEEECCCCCCH LTSCASVKNFDQPDNYLFFATKKGIVKKTSLKEYSNIRENGKIAIVLRDDDEVLTVANTN HHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCC GRQNIILASNNGNAICFDESQTRKTSRQSQGVIGMDLKKGEFLIGAALFDPNSKDQSILV CCEEEEEEECCCCEEEECCHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCCCCEEEE MTEKGYGKITSVNQYRIQSRNGKGSKTIKINSKTGRLIALKTAASSQDLIISSDKGQVIR EEECCCCCEECCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCEEE VSISDIKNTKHKATQGTKIIKLKTGHKAVLVAVESKIND EEHHHCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCC >Mature Secondary Structure MINQNPNLNQGKIKEVNLSAEMRKSFLSYAMSVIVARALPDIQDGLKPVQRRILYGMKEL CCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH SVYSNSSYKKAARIVGDVMGKYHPHGDSSIYEAMVRMSQDFSYRYPLVDGHGNFGSIDGH HEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCEEECCCCCCCCCCC KAAAMRYTEVKMAKIAMELIKNIDKETIEFVDNYDGSEKEPLVLPTAIPNLLINGATGIA HHHHEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCHHEECCCCCEE VGMATKIPTHNLAEVVDGLIAYIKDKNISILGLMQYIKGPDFPTGGELLGLKGLENAYKT EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCHHHHHC GQGSVIIKAKTHILEEKGKTLIVVTEIPYQIKKSALIEKIAFLVKDKVIEGITDLRDESS CCCCEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC RQGMKIVIELKKNANSKVILNQLYKHSPLRISFGINMVALVDKKPQLVSLKTILEAFFNF CCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCEEEEEECCCCCEEHHHHHHHHHHCC RIQVINKQKFFELKKAQARKHLVFAFLTILKDIQNAIKLIKNSSDTKDAQQKLMDQYQFD EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH AIQSKAILEMSLQRLSNQETQKLFIEEQKLTKEIAECQSIIESQPKKEKILEKELLEIKK HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH KYQDERRTVLNFDAALDDKDEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGGKGAAGM HHHHHHCEEEEECCCCCCCCHHHHCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCCCCC KIYEEDFIEHLLFTSTHNFLLFFTNKGRVYQLKGYQINLSDKSSKGIPLVNLLNLKPGET EEHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECEEEEECCCCCCCCCEEEEECCCCCCH LTSCASVKNFDQPDNYLFFATKKGIVKKTSLKEYSNIRENGKIAIVLRDDDEVLTVANTN HHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCC GRQNIILASNNGNAICFDESQTRKTSRQSQGVIGMDLKKGEFLIGAALFDPNSKDQSILV CCEEEEEEECCCCEEEECCHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCCCCEEEE MTEKGYGKITSVNQYRIQSRNGKGSKTIKINSKTGRLIALKTAASSQDLIISSDKGQVIR EEECCCCCEECCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCEEE VSISDIKNTKHKATQGTKIIKLKTGHKAVLVAVESKIND EEHHHCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10427704; 11058132 [H]