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The map label for this gene is codA

Identifier: 170757723

GI number: 170757723

Start: 2213001

End: 2214266

Strand: Reverse

Name: codA

Synonym: CLD_2565

Alternate gene names: 170757723

Gene position: 2214266-2213001 (Counterclockwise)

Preceding gene: 170755152

Following gene: 170757256

Centisome position: 55.94

GC content: 29.78

Gene sequence:

>1266_bases
ATGTTAATAAAAAATGTTAAACTTACAGATAAAAATGAATTAGTTAATATAAGAATTGAAAATGGTATATTTAAAGAAAT
AAAAAATAATTTAGAAGCATATAAAGATGAGGAAATTATAGATGGAAAAGGTAATCTGGCTCTTCCACCTTTTATAGAAC
CCCATGTCCATTTAGATACAACTCTTACAGCAGGAGAACCAAATTGGAATGAAAGTGGAACTTTGTTTGAAGGAATACAA
AGATGGTCTGAAAGAAAAGCTTTTTTAACAAAAGAAGATGTAAAAAAAAGAGCTAAAAAGGCATTAAGCTGGCAAATAGC
TAATGGTATACAACATGTTAGAACTCACGTTGATACAACGGATGAATCATTATTAGCACTAAAGGCTATGTTAGAAGTTA
AAGAAGAAATGAAAGACTATGTGGATATACAAATAGTAGCTTTCCCTCAAGAGGGAATTTTATCTTATCCAAGAGGCTTA
GAACTTTTAGAAGAGGCTTTAAAATTAGGAGCTGATGTAGTTGGAGCTATACCACATTTTGAATTTACTAGAGAATATGG
AGTAGAATCAATTAATAAAATATTTGAACTTGCAAAAAAATATGATGCATTGATAGATGTTCATTGTGATGAAATTGACG
ATGAACAATCAAGATTCTTAGAAACTGTAGCTACTAGGGCATTAGAAACAGGAATGAAAAATAAAGTTACAGCTAGTCAT
ACTACAGCTATGCATTCTTATAACAATGCTTATACATATAAATTGTTTAGACTTTTAAAAATGTCTGATATAAACTTTGT
TGCCAATCCTCTTGTAAATACACATTTACAAGGAAGGTTTGATACATATCCAAAGCGTAGAGGAGTTACTAGAGTAAAAG
AATTAAAAGATGCTAATATTAATGTTTGTTTTGGACATGATGATATTTTTGATCCATGGTATCCACTTGGAACTGGTAAT
ATGCTTCAAGTGTTGCATTTGGGATTACACGTGTGTCAAATTATGGGATATAATGAGATAGATGATTCTATTAAATTTAT
AACAACTAATTCAGCAAAAACTTTAAATATAGAAAATAAGTATGGTATAGAAGTAGGTAAGTCGGGTAATCTTATAATTT
TACCAGCTGAAAATGGCTATGATGCTATAAGACGTCAAGTTCCTGTTTGTTACTCTATAAGAGGTGGGAAAATAATAAGT
AAGACAGAACCATCTTTCACTAAGGTATATTTAGGAGAAGAAATTAACGTGAATTTTAAAAAATAA

Upstream 100 bases:

>100_bases
AAAGCTATCAAAGAAAAAACACAAAAAAATGTACAGTGTGATGAGTACGCTGCTTAATATTAAGATGATTTTTTAGTGAT
ATTAATAAGAGGGTGAATAT

Downstream 100 bases:

>100_bases
ATATGATAATGATAATATTTTAAAGCTCTTGAGGTATTTATTTACACTCAAGGGCTTTTTATTATAAGTATCCGAGAAAC
TGTCTTACGAGTATTAAATG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLIKNVKLTDKNELVNIRIENGIFKEIKNNLEAYKDEEIIDGKGNLALPPFIEPHVHLDTTLTAGEPNWNESGTLFEGIQ
RWSERKAFLTKEDVKKRAKKALSWQIANGIQHVRTHVDTTDESLLALKAMLEVKEEMKDYVDIQIVAFPQEGILSYPRGL
ELLEEALKLGADVVGAIPHFEFTREYGVESINKIFELAKKYDALIDVHCDEIDDEQSRFLETVATRALETGMKNKVTASH
TTAMHSYNNAYTYKLFRLLKMSDINFVANPLVNTHLQGRFDTYPKRRGVTRVKELKDANINVCFGHDDIFDPWYPLGTGN
MLQVLHLGLHVCQIMGYNEIDDSIKFITTNSAKTLNIENKYGIEVGKSGNLIILPAENGYDAIRRQVPVCYSIRGGKIIS
KTEPSFTKVYLGEEINVNFKK

Sequences:

>Translated_421_residues
MLIKNVKLTDKNELVNIRIENGIFKEIKNNLEAYKDEEIIDGKGNLALPPFIEPHVHLDTTLTAGEPNWNESGTLFEGIQ
RWSERKAFLTKEDVKKRAKKALSWQIANGIQHVRTHVDTTDESLLALKAMLEVKEEMKDYVDIQIVAFPQEGILSYPRGL
ELLEEALKLGADVVGAIPHFEFTREYGVESINKIFELAKKYDALIDVHCDEIDDEQSRFLETVATRALETGMKNKVTASH
TTAMHSYNNAYTYKLFRLLKMSDINFVANPLVNTHLQGRFDTYPKRRGVTRVKELKDANINVCFGHDDIFDPWYPLGTGN
MLQVLHLGLHVCQIMGYNEIDDSIKFITTNSAKTLNIENKYGIEVGKSGNLIILPAENGYDAIRRQVPVCYSIRGGKIIS
KTEPSFTKVYLGEEINVNFKK
>Mature_421_residues
MLIKNVKLTDKNELVNIRIENGIFKEIKNNLEAYKDEEIIDGKGNLALPPFIEPHVHLDTTLTAGEPNWNESGTLFEGIQ
RWSERKAFLTKEDVKKRAKKALSWQIANGIQHVRTHVDTTDESLLALKAMLEVKEEMKDYVDIQIVAFPQEGILSYPRGL
ELLEEALKLGADVVGAIPHFEFTREYGVESINKIFELAKKYDALIDVHCDEIDDEQSRFLETVATRALETGMKNKVTASH
TTAMHSYNNAYTYKLFRLLKMSDINFVANPLVNTHLQGRFDTYPKRRGVTRVKELKDANINVCFGHDDIFDPWYPLGTGN
MLQVLHLGLHVCQIMGYNEIDDSIKFITTNSAKTLNIENKYGIEVGKSGNLIILPAENGYDAIRRQVPVCYSIRGGKIIS
KTEPSFTKVYLGEEINVNFKK

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=420, Percent_Identity=67.6190476190476, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1786517, Length=396, Percent_Identity=22.7272727272727, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47839; Mature: 47839

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKNVKLTDKNELVNIRIENGIFKEIKNNLEAYKDEEIIDGKGNLALPPFIEPHVHLDT
CCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEE
TLTAGEPNWNESGTLFEGIQRWSERKAFLTKEDVKKRAKKALSWQIANGIQHVRTHVDTT
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DESLLALKAMLEVKEEMKDYVDIQIVAFPQEGILSYPRGLELLEEALKLGADVVGAIPHF
HHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCH
EFTREYGVESINKIFELAKKYDALIDVHCDEIDDEQSRFLETVATRALETGMKNKVTASH
HHHHHHCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH
TTAMHSYNNAYTYKLFRLLKMSDINFVANPLVNTHLQGRFDTYPKRRGVTRVKELKDANI
HHHHHCCCCHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCCCCCCHHCCCHHHHHHCCCCE
NVCFGHDDIFDPWYPLGTGNMLQVLHLGLHVCQIMGYNEIDDSIKFITTNSAKTLNIENK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCC
YGIEVGKSGNLIILPAENGYDAIRRQVPVCYSIRGGKIISKTEPSFTKVYLGEEINVNFK
CCEEECCCCCEEEEECCCCHHHHHHCCCEEEEECCCEEEECCCCCEEEEEECCEEEEEEC
K
C
>Mature Secondary Structure
MLIKNVKLTDKNELVNIRIENGIFKEIKNNLEAYKDEEIIDGKGNLALPPFIEPHVHLDT
CCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEE
TLTAGEPNWNESGTLFEGIQRWSERKAFLTKEDVKKRAKKALSWQIANGIQHVRTHVDTT
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DESLLALKAMLEVKEEMKDYVDIQIVAFPQEGILSYPRGLELLEEALKLGADVVGAIPHF
HHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCH
EFTREYGVESINKIFELAKKYDALIDVHCDEIDDEQSRFLETVATRALETGMKNKVTASH
HHHHHHCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH
TTAMHSYNNAYTYKLFRLLKMSDINFVANPLVNTHLQGRFDTYPKRRGVTRVKELKDANI
HHHHHCCCCHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCCCCCCHHCCCHHHHHHCCCCE
NVCFGHDDIFDPWYPLGTGNMLQVLHLGLHVCQIMGYNEIDDSIKFITTNSAKTLNIENK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCC
YGIEVGKSGNLIILPAENGYDAIRRQVPVCYSIRGGKIISKTEPSFTKVYLGEEINVNFK
CCEEECCCCCEEEEECCCCHHHHHHCCCEEEEECCCEEEECCCCCEEEEEECCEEEEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]