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The map label for this gene is rpiR [C]

Identifier: 170757634

GI number: 170757634

Start: 346070

End: 346837

Strand: Reverse

Name: rpiR [C]

Synonym: CLD_0483

Alternate gene names: 170757634

Gene position: 346837-346070 (Counterclockwise)

Preceding gene: 170756862

Following gene: 170755946

Centisome position: 8.76

GC content: 26.82

Gene sequence:

>768_bases
ATGATAGAAGGCTTAGATGAAAAAATTTTAAAAGAACTAACTAAAAATGAAAAAGATTTATTAAATTATATTAATTCTAA
TAATTTTAAGATTTATAAAATGAGTATAAATGAATTTGCACAAAGCACCTATGTATCTACTGCAACTGTTTTACGATTGT
GTAAAAAATTAGGTTTTAATGGGTTTAATGAACTAAAATTTAATCTAAAAAAATCTCTAACTTTAAAAAATAATGGCTAT
GATTCTTCTATAGGACTTAATGGATTACTTTCTAGACGTCTTTTAGAATTAAAAGAAACTATGATATCTTTAAATTTGGA
ACAATTAGATAGCATTGTAGACTATCTTTGCAGCGATAAAAATATTCATATATTTGGTAGGGGCCTTACTCAAATGTCTT
TAGAATATCTTTATAACATATTAATATCCTTAAACAGACAATGTATGTTTTACCTTGATCCTCCACTTGTTTACCAAACT
GCTTCTCAAATGGATGAGAATGACGTATTTATAATTGGAAGTTTTGGAGGTTCAACAGACCCTATTGTTAAAGCAGTAGA
AATTAGTAAAGAAAACCCTGGTACTGTTATAGCTATTACTTCTAATCCTAATAGTGAGTTAGCTAAAAAAGCTGATATTG
TTTTAATTGGGGAAACTCAAAATAGATTTTTTTCTGGCATTGATATTAACTCTAGGCTATCCATACAATTCATAGTAGAA
ATAATTGTGGAATTATATATGTCACGTATGAATATTGTTTCTCATTAG

Upstream 100 bases:

>100_bases
AACCTGTATTTTCTATATTGTAGATATGATAATAGAATGTTATATTAAATATTTAGATAAATCAAAATTTAATAATTTAT
ATTAAAAGGAGAACTAGGTC

Downstream 100 bases:

>100_bases
TTTTATAAAAATAGCAACATTTTAAGTTGCTATTTTTATATTTATATAATTTAATATTTCATAGCTTCTTTTACTTGCTT
TGCTACTTTTTCAACTTTAG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIEGLDEKILKELTKNEKDLLNYINSNNFKIYKMSINEFAQSTYVSTATVLRLCKKLGFNGFNELKFNLKKSLTLKNNGY
DSSIGLNGLLSRRLLELKETMISLNLEQLDSIVDYLCSDKNIHIFGRGLTQMSLEYLYNILISLNRQCMFYLDPPLVYQT
ASQMDENDVFIIGSFGGSTDPIVKAVEISKENPGTVIAITSNPNSELAKKADIVLIGETQNRFFSGIDINSRLSIQFIVE
IIVELYMSRMNIVSH

Sequences:

>Translated_255_residues
MIEGLDEKILKELTKNEKDLLNYINSNNFKIYKMSINEFAQSTYVSTATVLRLCKKLGFNGFNELKFNLKKSLTLKNNGY
DSSIGLNGLLSRRLLELKETMISLNLEQLDSIVDYLCSDKNIHIFGRGLTQMSLEYLYNILISLNRQCMFYLDPPLVYQT
ASQMDENDVFIIGSFGGSTDPIVKAVEISKENPGTVIAITSNPNSELAKKADIVLIGETQNRFFSGIDINSRLSIQFIVE
IIVELYMSRMNIVSH
>Mature_255_residues
MIEGLDEKILKELTKNEKDLLNYINSNNFKIYKMSINEFAQSTYVSTATVLRLCKKLGFNGFNELKFNLKKSLTLKNNGY
DSSIGLNGLLSRRLLELKETMISLNLEQLDSIVDYLCSDKNIHIFGRGLTQMSLEYLYNILISLNRQCMFYLDPPLVYQT
ASQMDENDVFIIGSFGGSTDPIVKAVEISKENPGTVIAITSNPNSELAKKADIVLIGETQNRFFSGIDINSRLSIQFIVE
IIVELYMSRMNIVSH

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=229, Percent_Identity=20.9606986899563, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788767, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788159, Length=220, Percent_Identity=25.9090909090909, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28896; Mature: 28896

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGLDEKILKELTKNEKDLLNYINSNNFKIYKMSINEFAQSTYVSTATVLRLCKKLGFN
CCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
GFNELKFNLKKSLTLKNNGYDSSIGLNGLLSRRLLELKETMISLNLEQLDSIVDYLCSDK
CCHHHHEEHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NIHIFGRGLTQMSLEYLYNILISLNRQCMFYLDPPLVYQTASQMDENDVFIIGSFGGSTD
CEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCC
PIVKAVEISKENPGTVIAITSNPNSELAKKADIVLIGETQNRFFSGIDINSRLSIQFIVE
HHEEEEEECCCCCCEEEEEECCCCHHHHHHCCEEEEECCCCCEEECCCCCCCHHHHHHHH
IIVELYMSRMNIVSH
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEGLDEKILKELTKNEKDLLNYINSNNFKIYKMSINEFAQSTYVSTATVLRLCKKLGFN
CCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
GFNELKFNLKKSLTLKNNGYDSSIGLNGLLSRRLLELKETMISLNLEQLDSIVDYLCSDK
CCHHHHEEHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NIHIFGRGLTQMSLEYLYNILISLNRQCMFYLDPPLVYQTASQMDENDVFIIGSFGGSTD
CEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCC
PIVKAVEISKENPGTVIAITSNPNSELAKKADIVLIGETQNRFFSGIDINSRLSIQFIVE
HHEEEEEECCCCCCEEEEEECCCCHHHHHHCCEEEEECCCCCEEECCCCCCCHHHHHHHH
IIVELYMSRMNIVSH
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]