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The map label for this gene is cat

Identifier: 170757539

GI number: 170757539

Start: 2170059

End: 2170724

Strand: Reverse

Name: cat

Synonym: CLD_2604

Alternate gene names: 170757539

Gene position: 2170724-2170059 (Counterclockwise)

Preceding gene: 170754262

Following gene: 170756302

Centisome position: 54.84

GC content: 27.63

Gene sequence:

>666_bases
ATGAAGTTTAATTTAATAGATAAAGAAAATTGGAGTAGAAAACCTTATTTTGATTACTATATGAATAATATCAAATGTAC
TTATAGCATGACTGCTAATATTGAAATTACAGACTTACTTATGAAAATAAAAAGAAATAATATAAAACTATATCCTATAC
TAATTTATATGACTTCAAAGATAATAAACAAGCATGAAGAATTACGTACTTCTTTTGATGAAAAGGGAAACTTAGGTTAT
TGGGAAAGTATGAGCCCTTCCTTCACTATATTTCATAAGGATGATGAGAGTTTTAGCAACATTTGGACAGAGTATTCTGA
TGATTTTAAAACATTTTATAATAATTGTCTTCAGGATATAGAAAAACATAGTGGTGTAAAGAAACTTTTCGCAAAAGAAA
ATCAGCCTAAAAATACATTTCCTGTTTCTTGTGTCCCTTGGTTTAGTTTTACAGGGGCTAATCTTAATATTTATCCAGAT
GAAGAATATCCATATCTTTTGCCAATAATCACTTATAGTAAATATTTTGCACAGAGTGCTAAAGACTTAATACCTATTTC
TCTACAGATGCATCATGCTGTTTGTGATGGTTATCATGTAACTAGATTTTTAAATGAATTACAATCCATGGCACATAATT
TTAAAGAGTGGCTAATAATTAAATGA

Upstream 100 bases:

>100_bases
TCATAATAGACTATACTGCATATATATAGTGTAGGTATAAAATGCTTTTACAAGAGGTGGATAATACTTAGCGTAAGATA
TATGAGTAGGAGTTGATTTT

Downstream 100 bases:

>100_bases
ATGCTATGGGTAAAAATGTAAAACTGCTTAAAATGCAGGGATACACTTTTAGTTATAGAATAAGTAGAATATAATTCTAC
TTAGATATGTTTAAGTAGGA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKFNLIDKENWSRKPYFDYYMNNIKCTYSMTANIEITDLLMKIKRNNIKLYPILIYMTSKIINKHEELRTSFDEKGNLGY
WESMSPSFTIFHKDDESFSNIWTEYSDDFKTFYNNCLQDIEKHSGVKKLFAKENQPKNTFPVSCVPWFSFTGANLNIYPD
EEYPYLLPIITYSKYFAQSAKDLIPISLQMHHAVCDGYHVTRFLNELQSMAHNFKEWLIIK

Sequences:

>Translated_221_residues
MKFNLIDKENWSRKPYFDYYMNNIKCTYSMTANIEITDLLMKIKRNNIKLYPILIYMTSKIINKHEELRTSFDEKGNLGY
WESMSPSFTIFHKDDESFSNIWTEYSDDFKTFYNNCLQDIEKHSGVKKLFAKENQPKNTFPVSCVPWFSFTGANLNIYPD
EEYPYLLPIITYSKYFAQSAKDLIPISLQMHHAVCDGYHVTRFLNELQSMAHNFKEWLIIK
>Mature_221_residues
MKFNLIDKENWSRKPYFDYYMNNIKCTYSMTANIEITDLLMKIKRNNIKLYPILIYMTSKIINKHEELRTSFDEKGNLGY
WESMSPSFTIFHKDDESFSNIWTEYSDDFKTFYNNCLQDIEKHSGVKKLFAKENQPKNTFPVSCVPWFSFTGANLNIYPD
EEYPYLLPIITYSKYFAQSAKDLIPISLQMHHAVCDGYHVTRFLNELQSMAHNFKEWLIIK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 26356; Mature: 26356

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNLIDKENWSRKPYFDYYMNNIKCTYSMTANIEITDLLMKIKRNNIKLYPILIYMTSK
CCCCCCCCCCCCCCCHHHHHHCCEEEEEEEEECCHHHHHHHHHHHCCEEEEEEHHHHHHH
IINKHEELRTSFDEKGNLGYWESMSPSFTIFHKDDESFSNIWTEYSDDFKTFYNNCLQDI
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHH
EKHSGVKKLFAKENQPKNTFPVSCVPWFSFTGANLNIYPDEEYPYLLPIITYSKYFAQSA
HHHCCHHHHHHCCCCCCCCCCCEEECCEEECCCEEEECCCCCCCEEEHHHHHHHHHHHHH
KDLIPISLQMHHAVCDGYHVTRFLNELQSMAHNFKEWLIIK
CCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEC
>Mature Secondary Structure
MKFNLIDKENWSRKPYFDYYMNNIKCTYSMTANIEITDLLMKIKRNNIKLYPILIYMTSK
CCCCCCCCCCCCCCCHHHHHHCCEEEEEEEEECCHHHHHHHHHHHCCEEEEEEHHHHHHH
IINKHEELRTSFDEKGNLGYWESMSPSFTIFHKDDESFSNIWTEYSDDFKTFYNNCLQDI
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHH
EKHSGVKKLFAKENQPKNTFPVSCVPWFSFTGANLNIYPDEEYPYLLPIITYSKYFAQSA
HHHCCHHHHHHCCCCCCCCCCCEEECCEEECCCEEEECCCCCCCEEEHHHHHHHHHHHHH
KDLIPISLQMHHAVCDGYHVTRFLNELQSMAHNFKEWLIIK
CCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1489203 [H]