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The map label for this gene is 170756302

Identifier: 170756302

GI number: 170756302

Start: 2168807

End: 2169946

Strand: Reverse

Name: 170756302

Synonym: CLD_2605

Alternate gene names: NA

Gene position: 2169946-2168807 (Counterclockwise)

Preceding gene: 170757539

Following gene: 170755908

Centisome position: 54.82

GC content: 32.98

Gene sequence:

>1140_bases
ATGAAGGTACCATATGTTATGACACCAGGCCCTACCATGGTAAGAGAAAATGTTAGAATGGCAAGGGTTATGGAAACAAC
AAACCCAGATTTAGATTTACAATTTTATGATTATTATAAAGAAACCTGTGAAAAAATAGGGGGATTTTTAAAAACTAAAA
ATGAAGTAAGGATATTAAGTGGAGAGGGAATATTAGGACTGGAAGCAGCTTGTGCTTCATTAACAGAAAAAGGTGACAGA
ATTCTTGTAATTGACAATGGAATTTTTGGTGAAGGCTTTGCAGATTTTGTAGAAATATATGGAGGAGAAGCAGTATTTTT
TAAAGGAGATAGAAAAAGAGATATAGATATAGAAAAGTTGAAAGAATTTCTAGAAAAGGATAGTAACTTTAAATATGCTA
CTGTTGTACACTGTGATACTCCCTCAGGGGTTATTAATGATGTATCAAAAATATGTCCAATGCTTAAAGAAAAGGGCATA
ATAACTGTAGTAGATTCTGTATCTGCCATGGGTGGACAGGAGCTAAAGGTGGATGAATGGAAAATAGATATGGTACTTGG
TGGATCTCAAAAATGTATGTCAGCCCCTCCAGGCCTTTCATTTCTTAGTATAAGTGAAGATGCCTTTAAAACTATGGAAG
AAAGAAGAACACCTATAGCATCATATTACTGTAATCTCCTTGTATGGAAGGATTATTATAAAAATAAATGGTTCCCATAC
ACTCAACCTATAAGTGATATAGTTGGGTTAAGAGTAGCGGTGGATAATATTTTAAAGGATAGAGACATACTATCAAGACA
CAATAATATAGCAAAAGCTTGTAGAGAGGCTATAGTAGAGAGTGGACTTAAGCTTTATTTAGAAAAGGGTTATTCTAACA
CTGTTACTGTTATAGAACTACCTAAAGAAATAGAGAATAAAGCTTTAAGAACATATATGCAGGATAAATACAATGTAATC
ATAGCAGGTTCCTTTGGATATCTTCATGGTAAGGTTATAAGAATAGGTCATATGGGTGAAAATGCTAAAGTGGATAGAAT
GGCTTATACATTATTTGCACTTAAAAATAGCTTAGAGCATTTAGGATACAAACTAAGGGCTAATATTGGAGAAGTTTTCT
TACAAAAAGTTATGGAGTAA

Upstream 100 bases:

>100_bases
AAAATGTAAAACTGCTTAAAATGCAGGGATACACTTTTAGTTATAGAATAAGTAGAATATAATTCTACTTAGATATGTTT
AAGTAGGAGGAGTTGATTTT

Downstream 100 bases:

>100_bases
GAGTGAATATTATTATTTCAAAAATTATCATTTTTGATCTTATATTAGCTATAATTTATTTTGTACAAGGACTTAAAAAC
TCAAGAGAAAATAGATAGGA

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKVPYVMTPGPTMVRENVRMARVMETTNPDLDLQFYDYYKETCEKIGGFLKTKNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSNFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TQPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIENKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDRMAYTLFALKNSLEHLGYKLRANIGEVFLQKVME

Sequences:

>Translated_379_residues
MKVPYVMTPGPTMVRENVRMARVMETTNPDLDLQFYDYYKETCEKIGGFLKTKNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSNFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TQPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIENKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDRMAYTLFALKNSLEHLGYKLRANIGEVFLQKVME
>Mature_379_residues
MKVPYVMTPGPTMVRENVRMARVMETTNPDLDLQFYDYYKETCEKIGGFLKTKNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSNFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TQPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIENKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDRMAYTLFALKNSLEHLGYKLRANIGEVFLQKVME

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=364, Percent_Identity=26.0989010989011, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17536281, Length=320, Percent_Identity=27.8125, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321079, Length=379, Percent_Identity=26.6490765171504, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17530823, Length=383, Percent_Identity=28.1984334203655, Blast_Score=147, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42828; Mature: 42828

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPYVMTPGPTMVRENVRMARVMETTNPDLDLQFYDYYKETCEKIGGFLKTKNEVRILS
CCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GEGILGLEAACASLTEKGDRILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKL
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KEFLEKDSNFKYATVVHCDTPSGVINDVSKICPMLKEKGIITVVDSVSAMGGQELKVDEW
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCEEECCE
KIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
EEEEEECCCHHHCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHEEEEHHHCCCCCCC
TQPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEEEC
PKEIENKALRTYMQDKYNVIIAGSFGYLHGKVIRIGHMGENAKVDRMAYTLFALKNSLEH
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGYKLRANIGEVFLQKVME
CCCHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MKVPYVMTPGPTMVRENVRMARVMETTNPDLDLQFYDYYKETCEKIGGFLKTKNEVRILS
CCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GEGILGLEAACASLTEKGDRILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKL
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KEFLEKDSNFKYATVVHCDTPSGVINDVSKICPMLKEKGIITVVDSVSAMGGQELKVDEW
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCEEECCE
KIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
EEEEEECCCHHHCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHEEEEHHHCCCCCCC
TQPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEEEC
PKEIENKALRTYMQDKYNVIIAGSFGYLHGKVIRIGHMGENAKVDRMAYTLFALKNSLEH
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGYKLRANIGEVFLQKVME
CCCHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]