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The map label for this gene is sigW [H]

Identifier: 170757425

GI number: 170757425

Start: 2497715

End: 2498230

Strand: Reverse

Name: sigW [H]

Synonym: CLD_2263

Alternate gene names: 170757425

Gene position: 2498230-2497715 (Counterclockwise)

Preceding gene: 170756366

Following gene: 170755174

Centisome position: 63.11

GC content: 29.26

Gene sequence:

>516_bases
GTGGTGATAGTTATTGAAAAAGAACAATTTGCAGACTGTATAAAACAATATGAACGTTTAATTATTACTATTTGTCTATC
CTTTACAAAAAATTACTTTGATGCGGAAGATTTGGCACAGCAAACCTTTTTAGCTGCATATCAAAATTATGAAAGATTTG
ATGATAACAACTTTAAAGCTTGGATTACTACGATTGCTGCAAATAAGTGCAAGGATTATCTTAAGAGTAAAACAAGAACA
AACGTTAGTTTATCAGAGAAAGAGTATGAGAGTTTGAAAGATCATGGAGATTCTCCCGAGGAAACAGTAGTAAAAAAGAA
TACTATTGAGAGAATATATAGATTATGTAATAAGTTAAAAGAGCCTTATAGAACTGTAGCTATAAGCTATTTTTGTAAAG
ATATCAAACTCTCACATTTGGCAAAAGAAACTGGTAAAAATATTAAAACTTTAGAAACGCAACTTTATAGGTCAAAAAAA
TTACTAAAAGATTTATGGAAGGAGGAGTTTATGTGA

Upstream 100 bases:

>100_bases
TAGAAAATGTTATTCAGATAATTTTTAGTATAATTATACTAAATATTGAAGTGTTTTTTATTTCTCAATCGTTATATTAA
ATGTAAGGATATAAAAGAAG

Downstream 100 bases:

>100_bases
AGCCTACATTATTTAATAAAGAAGGACATTTAACTGACGATACAGTAAAGTTACTTAAACGTGGCACTCTTAAGGATGAA
GAATTGATTTCCATATTGGA

Product: ECF subfamily RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MVIVIEKEQFADCIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDDNNFKAWITTIAANKCKDYLKSKTRT
NVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKK
LLKDLWKEEFM

Sequences:

>Translated_171_residues
MVIVIEKEQFADCIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDDNNFKAWITTIAANKCKDYLKSKTRT
NVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKK
LLKDLWKEEFM
>Mature_171_residues
MVIVIEKEQFADCIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDDNNFKAWITTIAANKCKDYLKSKTRT
NVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKK
LLKDLWKEEFM

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20300; Mature: 20300

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVIEKEQFADCIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDDNNFKA
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
WITTIAANKCKDYLKSKTRTNVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKLLKDLWKEEFM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIVIEKEQFADCIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDDNNFKA
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
WITTIAANKCKDYLKSKTRTNVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKLLKDLWKEEFM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]