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The map label for this gene is cat [H]

Identifier: 170757311

GI number: 170757311

Start: 863445

End: 864068

Strand: Direct

Name: cat [H]

Synonym: CLD_0021

Alternate gene names: 170757311

Gene position: 863445-864068 (Clockwise)

Preceding gene: 170754791

Following gene: 170756496

Centisome position: 21.81

GC content: 27.08

Gene sequence:

>624_bases
ATGAATTTTAGAATTATTAACAAAAAAGATTGGGATAGAAAAGAATATTTTGAACATTATTTTTCTGAAGTTTCATGCAC
ATATAGTATGACTGTTAAATTGGATATTACAAAAATTAAAAATTCAAATCAAAAGCTATATCCAACAATATTATATTTTA
TTACAAAAGTAGTCAATAAACATAATGAATTTAGAACATCTTTTAACATGAATGGACAACTAGGTGTTTTTGAAGAAATG
ATTCCATGCTATACAGTATTTCATAAAGACACAGAAACCTTTTCTAATATCTGGACAGAGTACTCTGAGAATTATGATAT
TTTCTGCAAGTCATATGAAAAAGATATGCAGATGTTTAGTTCAGTAAAAGGATTGATAGCAAAACCAGATATACCTGCTA
ATAATTTTCCAGTGTCAATGGTACCATGGACATCATTTGATGGATTTAATCTAAACTTACAAAAAGGATATGAATATTTA
TTACCAATTTTCACTATTGGAAAATATTATAAAGAAAATGGTAGATACCTTTTACCATTAGCAATACAGGTTCATCATGC
TGTATGTGATGGATTTCATGTGTGTCGCTTTGTAAATGAATTACAGGAATTGATAAAAGGATAA

Upstream 100 bases:

>100_bases
TATAATTACTATTAATTAAGTTACGGTAGTATATAACTGTGAAGTAAAGATTATTTATATAATGAGCAGATAAATAGTAA
TTTGAAAGGAAGATACATAA

Downstream 100 bases:

>100_bases
ATTCCAATTTATAGAGTTGAAATAACATAGTTTTAGCTTTAATTATATCATATCTTTCTTATAAGATGACTTATTATAAA
AAACGAATATTTTATGAAAA

Product: chloramphenicol O-acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNKHNEFRTSFNMNGQLGVFEEM
IPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFSSVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYL
LPIFTIGKYYKENGRYLLPLAIQVHHAVCDGFHVCRFVNELQELIKG

Sequences:

>Translated_207_residues
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNKHNEFRTSFNMNGQLGVFEEM
IPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFSSVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYL
LPIFTIGKYYKENGRYLLPLAIQVHHAVCDGFHVCRFVNELQELIKG
>Mature_207_residues
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNKHNEFRTSFNMNGQLGVFEEM
IPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFSSVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYL
LPIFTIGKYYKENGRYLLPLAIQVHHAVCDGFHVCRFVNELQELIKG

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24549; Mature: 24549

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00100 CAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNK
CCEEECCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
HNEFRTSFNMNGQLGVFEEMIPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFS
CHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
SVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYLLPIFTIGKYYKENGRYLLPL
HHHCCEECCCCCCCCCCEEEECCCCCCCCEEEHHHCHHHHHHHHHHHHHHHCCCCEEEEE
AIQVHHAVCDGFHVCRFVNELQELIKG
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNK
CCEEECCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
HNEFRTSFNMNGQLGVFEEMIPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFS
CHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
SVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYLLPIFTIGKYYKENGRYLLPL
HHHCCEECCCCCCCCCCEEEECCCCCCCCEEEHHHCHHHHHHHHHHHHHHHCCCCEEEEE
AIQVHHAVCDGFHVCRFVNELQELIKG
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406372 [H]