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The map label for this gene is yycF [H]

Identifier: 170757250

GI number: 170757250

Start: 729825

End: 730508

Strand: Direct

Name: yycF [H]

Synonym: CLD_0149

Alternate gene names: 170757250

Gene position: 729825-730508 (Clockwise)

Preceding gene: 170755917

Following gene: 170757730

Centisome position: 18.44

GC content: 28.36

Gene sequence:

>684_bases
ATGGAATTTAAGGTTCTAGTAGTTGAAGATGAAATATCTATAAATGATATTTTAGTGTCTGCTCTAAGAGCAGATGGATA
TAAAGTTAAGGGGGTATTTTTAGCTAAAGATGCAAAAGATGCTTTAGATTTTTTTCACCCAGACTTAGTATTGTTGGATA
TAAATTTACCAGATGAAAGTGGTTTTGAATTATGTAGACATATAAATGATAAATGTTGTATTCCAATAATTATGTTAACT
GCCCGTAACGATATTGTGGACAAGGTTTTAGGTTTAGAACTAGGTGCTGATGATTACATTACTAAACCATTTAATATAAA
AGAAGTATTAACTAGGGTAAAGGTTGCAATAAGAAGAGTTAATAAGTATAAAGAAAAATCAGATGAAGAATTTATATATA
TAAATAAATTTGTTAAAGTGAATTTGGAAGGCAGAATTGTATTTAAAGATGATAAAGAAGTTAAACTAAAACCTCAGGAA
TATGAATTGTTAGAATTTTTTGTTAAAAATAGAAACATAGTTTTTTCAAGAGAAATTCTTTTAAATAAAGTCTGGGGATT
TGATTATGAAGGTGAGGTTAGAACAGTGGACGTTCATGTTAGAAGATTAAGAAGTAAGCTTGATAAAGAAAATGCCACAT
CTATCATAGACACTGCTTTTGGAATAGGATATGTAATGAGGTAG

Upstream 100 bases:

>100_bases
AGAGTTAGTAATATTCTTATATGTATTTTTAAAATATTGTATAATTTAGCTTTTTACATAGAGTTACTTATGTAAATGAA
AACAATAGGAGGAATTTATA

Downstream 100 bases:

>100_bases
CTTTATGAAAATAAGATATAAATTTATAACTGGTTTAATATTTATACTGATAGTTTCTATGATAGTAATGAATGTGGCAA
TAACACATGTTTTAAAGTCT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MEFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDEEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTAFGIGYVMR

Sequences:

>Translated_227_residues
MEFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDEEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTAFGIGYVMR
>Mature_227_residues
MEFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDEEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTAFGIGYVMR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=38.8646288209607, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.0869565217391, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=35.5555555555556, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.7826086956522, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=34.4978165938865, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.3333333333333, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=33.7662337662338, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=33.7777777777778, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=34.5132743362832, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=29.8245614035088, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=210, Percent_Identity=28.0952380952381, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=31.0606060606061, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26351; Mature: 26351

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDES
CCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCEEEEEEECCCCC
GFELCRHINDKCCIPIIMLTARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NKYKEKSDEEFIYINKFVKVNLEGRIVFKDDKEVKLKPQEYELLEFFVKNRNIVFSREIL
HHHHCCCCCCEEEEEEEEEEEECEEEEEECCCCEEECCHHHHHHHHHHHCCCEEEEHHHH
LNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTAFGIGYVMR
HHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECC
>Mature Secondary Structure
MEFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDES
CCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCEEEEEEECCCCC
GFELCRHINDKCCIPIIMLTARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NKYKEKSDEEFIYINKFVKVNLEGRIVFKDDKEVKLKPQEYELLEFFVKNRNIVFSREIL
HHHHCCCCCCEEEEEEEEEEEECEEEEEECCCCEEECCHHHHHHHHHHHCCCEEEEHHHH
LNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTAFGIGYVMR
HHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]