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The map label for this gene is clpX

Identifier: 170756735

GI number: 170756735

Start: 3508952

End: 3510241

Strand: Reverse

Name: clpX

Synonym: CLD_1301

Alternate gene names: 170756735

Gene position: 3510241-3508952 (Counterclockwise)

Preceding gene: 170754567

Following gene: 170756440

Centisome position: 88.68

GC content: 30.78

Gene sequence:

>1290_bases
ATGTCTAAATTAGATGAAAAAAAACAGTTGAAATGTTCATTCTGCGGCAAGACACAAGATCAAGTAAGACGACTTATAGC
AGGCCCAGGAGTATATATATGCGATGAATGCATAGAACTTTGCTCTGAAATAATAAATGATGAGTTTGAAGATGATATAC
AAGTGGATTTAACATCACTACCAAAACCCACAGAGATAAAGACTTATCTTGATCAATATGTTATAGGTCAAGAAGATGCT
AAAAAATCATTATCTGTAGCTGTGTATAATCATTACAAAAGGATAAATTCAAATACAAATAATGATGATGTAGAACTTCA
AAAGAGTAATATTCTTCTTTTAGGACCTACAGGTTCAGGAAAAACACTATTAGCACAAACATTAGCTAAGTTTTTAAATG
TACCTTTTGCTATAGCAGATGCTACAACACTTACAGAGGCTGGATATGTAGGAGAAGACGTAGAAAATATTCTTTTAAAG
CTTATTCAAAATGCTGATTATGATATAGAAAAAGCAGAAAAAGGAATAGTATATATAGACGAAATAGATAAGATAGCAAG
AAAATCAGAAAATCCTTCTATTACTAGAGATGTATCAGGTGAAGGGGTGCAACAAGCATTATTAAAAATTCTTGAAGGTA
CCGTAGCAGCTGTTCCACCTCAAGGTGGAAGAAAACATCCGCATCAAGAGTTTATACAAATAAATACTACAAATATATTA
TTTATTTGTGGTGGAGCTTTTGATGGGGTGGATAAGATAATAGAAAGAAGAACAAGAACTAGTTCTTTAGGATTTGGAGC
TGAAATTCAATCTAAGAAAGAAAAAGATTTAGGAAAACTTTTGAAAGATATTATGCCAGGAGATTTATTAAAATTTGGTT
TAATACCTGAATTTATTGGAAGATTACCTATAGTGGTTACTTTAGATAAATTAGATAGAGAAGCTCTAATAAAAATATTA
ACTGAACCTAAAAATGCTCTTGTAAAACAATATAAGAAATTGTTTGAATTAGATGACGTAGAATTAGAGTTTAACCAAGA
GGCATTAAAGGAAATTGCTGATGAAGCAATAAATAGAAACACTGGAGCTAGAGGTCTTAGAGCTATAATAGAAGACATGA
TGAGAGAAATTATGTTTGATATACCATCTCAAGAAAATATAGGTAAGGTAATAGTAAATGAGGATTGTATAAAAACTAAA
AAACCAGAGCTTATAGAGGCTGAAGGTGGTAAAAGATTACCTATTAAACCTAAAAAAGGTAAGAAAAGAAAAGATTCTGA
AACAGCGTAA

Upstream 100 bases:

>100_bases
ACAGAGAGAGATCATTTCTTAAGTGCAGAAGAAGCTAAAGAATATGGTTTAATTGATGAAGTTATTGATAAAAAGAAATA
ACCTTTAGTGAGGTGTAGAA

Downstream 100 bases:

>100_bases
AAATAACACCAAGATTTTATCTTGGTGTTATTTTTTACTATTATATTAAATGAATAAAATGCATTTTTGAATATATAAAG
AGGAAAAAGAACATAATAAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSLPKPTEIKTYLDQYVIGQEDA
KKSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSGKTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLK
LIQNADYDIEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNIL
FICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIGRLPIVVTLDKLDREALIKIL
TEPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRNTGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTK
KPELIEAEGGKRLPIKPKKGKKRKDSETA

Sequences:

>Translated_429_residues
MSKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSLPKPTEIKTYLDQYVIGQEDA
KKSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSGKTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLK
LIQNADYDIEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNIL
FICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIGRLPIVVTLDKLDREALIKIL
TEPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRNTGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTK
KPELIEAEGGKRLPIKPKKGKKRKDSETA
>Mature_428_residues
SKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSLPKPTEIKTYLDQYVIGQEDAK
KSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSGKTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLKL
IQNADYDIEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNILF
ICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIGRLPIVVTLDKLDREALIKILT
EPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRNTGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTKK
PELIEAEGGKRLPIKPKKGKKRKDSETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=337, Percent_Identity=50.4451038575668, Blast_Score=316, Evalue=3e-86,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=64.1791044776119, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=34.7417840375587, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.9807073954984, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=45.8333333333333, Blast_Score=274, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=37.9134860050891, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=430, Percent_Identity=39.7674418604651, Blast_Score=275, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=48.5981308411215, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=48.5981308411215, Blast_Score=300, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_CLOB1 (A7FYI1)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385554.1
- ProteinModelPortal:   A7FYI1
- STRING:   A7FYI1
- GeneID:   5395069
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3267
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   CBOT441770:CLB_3267-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47860; Mature: 47729

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSL
CCCCCCHHCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
PKPTEIKTYLDQYVIGQEDAKKSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCC
KTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDIEKAEKGIVYID
HHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEHH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHEEEECCEEE
FICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIG
EEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
RLPIVVTLDKLDREALIKILTEPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRN
CCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCC
TGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTKKPELIEAEGGKRLPIKPKKG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCCCCEEECCCCCCCCCCCCCC
KKRKDSETA
CCCCCCCCC
>Mature Secondary Structure 
SKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSL
CCCCCHHCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
PKPTEIKTYLDQYVIGQEDAKKSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCC
KTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDIEKAEKGIVYID
HHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEHH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHEEEECCEEE
FICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIG
EEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
RLPIVVTLDKLDREALIKILTEPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRN
CCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCC
TGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTKKPELIEAEGGKRLPIKPKKG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCCCCEEECCCCCCCCCCCCCC
KKRKDSETA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA