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The map label for this gene is fchA

Identifier: 170756609

GI number: 170756609

Start: 1297902

End: 1298534

Strand: Direct

Name: fchA

Synonym: CLD_3398

Alternate gene names: 170756609

Gene position: 1297902-1298534 (Clockwise)

Preceding gene: 170756187

Following gene: 170754644

Centisome position: 32.79

GC content: 29.86

Gene sequence:

>633_bases
GTGTTAGATAAAAGTTGTAAAGAATTTATAGATATTTTATCCTCTAAGGAACCTGTACCAGGTGGAGGCGGTGCTTGTGC
TTATGTAGGAGCTTTAGGTATGGCCTTAGGCAATATGGTAGCAAATCTTACTATAGGGAAGAAAAAATATAAAGATGTAG
AAGAGGATGTAAAAGAAATATTAAAAGAAGGAGAAATCTTAATACAGAAATTAGAGGAATTAGTAAATAAAGATGCTGAA
GTATTTTATCCATTATCTAAAGCTTATGGATTACCTAAAAATACAGAAGAGGAAAAAGCATATAAAGATAAAATTATGGA
AGAGGCATTATATAACGCTAGTTTAGTGCCTCTAGAAATAGCTAAATGTGCAGCAGAGACCATAAATCTTCATTATAAAT
TAGCTAAGATAGGAACTAGAATTGCTATAAGTGATGTAGGTGTAGGAGTGCTATTTTGCAAAACAGCACTAGAAGCTTCT
AAGTTAAATGTATATATAAATACTGGTATGATGAAAAATAATGATATAAAAAATTCTTTGGAAGAAGAAATCAACACCTT
AGTTTCTAAATATTCAACTAAGGCAGATAAAGTTTATAGTTATGTAGAAAATTTAATAAGGGGAAATGAATAA

Upstream 100 bases:

>100_bases
ATGTATAATATATATTAGTATTATAGAAAGTGTAATTAATTTAGTATAGTATTTAGTATTTACTATAATAAGAATAAATT
AATAAGGTAGGTGGATTTTT

Downstream 100 bases:

>100_bases
TGACTAAAATATTATATGGAAATGAAGTAGCTTTAAAAATAAAGGAAGATTTAAATTTAAGAATGGACAAATTAAAAGAA
AAAAATATAATACCTAAGTT

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETINLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE

Sequences:

>Translated_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETINLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE
>Mature_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETINLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=167, Percent_Identity=26.9461077844311, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI11140815, Length=167, Percent_Identity=26.9461077844311, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23142; Mature: 23142

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKEGEILIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETINLHYKLAKIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
EEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKEGEILIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETINLHYKLAKIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
EEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]