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The map label for this gene is yvrG [H]

Identifier: 170756485

GI number: 170756485

Start: 1078335

End: 1079756

Strand: Direct

Name: yvrG [H]

Synonym: CLD_3594

Alternate gene names: 170756485

Gene position: 1078335-1079756 (Clockwise)

Preceding gene: 170755642

Following gene: 170757277

Centisome position: 27.24

GC content: 24.82

Gene sequence:

>1422_bases
ATGAAAAATAATATGAAGTGGAGAATTACAGGAAGGTTCTTAGTAACAGTTATTTGCGTAGTTATAACTGTAGTTATAAT
AAATATTGTATCTTTATCAGGTCTTGTAATTTATAGAAATGTTACTAATATTGGTATGACTAAATATGATATTGAGGGGA
TTGTTAGAAATTTTTCTTCTAATATTAAAGAAATAGATAATAAAATATATATTGATGATAAAGGCAAAGCTATATTAGAT
AGTAAAAATGGGTGGATACAGATTATAGACGCTAATAATAATGAAGTTTACAATTATAAAAAACCTTCATATATAAAAAA
TAAGCCTACTGCTGCAGAAATAGTAAATTTATATAAATATAAAACTTCTGATAAACGAAATGAAGTGTCTACTAATTTTG
TAGCTGAAAAAAATATAGGCAATAAAAGATTAACTTATATTATAGGATTTGGGGATAATGACATAACCAAATATGTAATT
ACTACTAGGAACTCAGAAGTAATCCAAATTATAAAATCTGCTACAATAATAATTATTATAGTAGATGGGATTATAGCTTT
AATTTTTGGATATCTTTTTATTAGAAAATTAACTAATCCTTTAGGAGAGATATTATTAGGCATAAAGAAACTAGAAAATG
AAGAATATGATTTATATTATGAAGCTAAAGGAATGTATAATGATTTGTATTATAGTTTAAATAATTTATCAGATAGATTA
CAAGAAAATAAAAGGAATAGAAAAAAGCTGGATAATATGAGAGAAGAATGGATTTCAAATATTTCTCATGATATAAAAAC
TCCATTAGCTTCTATCCAAGGCTATGCGGAAATAATAAAAGATGAAGATTATGATTTTACAAAAGAGGAGATAGGAGAGT
ATGCTGAAATCATAGAAAATAAATCTAAATATATTAAAGAATTAGTAGAAGATTTAAATTTATCTACTAGATTAAAAAAT
AATACTTTAACTTTAAATAAGGAAAAAATTAATTTAGCTAATTTAATAAAGGATATTATAATAGATATATTAAATGATAC
CAGATATGAAAATAGGGAAATAGATTTTCACTGTGAGAATGACAATATTGAAATAAATGGAGACAGAATTCTTATAAGAA
GGGCTATAATTAATATTTTATTTAATGCCATTGTGCACAATAGTGAGGATGTAAAGATAGATGTTACACTAAAAAAACAG
GATAAGATAAGTATAATTGTTGAAGACAATGGTAGGGGAATAAAAGGAGAAGAGTTAAATAGAATTTTTGATAGATATTA
TAGAGGAACTAATACAGGAGAGAGACATAAAGGTTCTGGATTAGGAATGGCTATATCAAAAGAAACAATTGTTGCCCATG
GAGGGGATATAACTATTGAAAGTGAACTAGGCAAGGGAACCAAAGTAAATATATTAATATAA

Upstream 100 bases:

>100_bases
GTCCACATTAGAAGACTTAGAGAAAAAATTGAAAAAGAACCATCAAGACCAGAATATTTAATAAATGTTAAGGGATTAGG
ATACAAATTGGTGATAAAAA

Downstream 100 bases:

>100_bases
TTAAGAAAATAAATATCTAGAAAAATAATTAGAATACTTTATTTGTGGACTAATATTTAAACGTGAAGTAAACAGGACTT
TTATTTAGAAAAAAGAGTAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKNNMKWRITGRFLVTVICVVITVVIINIVSLSGLVIYRNVTNIGMTKYDIEGIVRNFSSNIKEIDNKIYIDDKGKAILD
SKNGWIQIIDANNNEVYNYKKPSYIKNKPTAAEIVNLYKYKTSDKRNEVSTNFVAEKNIGNKRLTYIIGFGDNDITKYVI
TTRNSEVIQIIKSATIIIIIVDGIIALIFGYLFIRKLTNPLGEILLGIKKLENEEYDLYYEAKGMYNDLYYSLNNLSDRL
QENKRNRKKLDNMREEWISNISHDIKTPLASIQGYAEIIKDEDYDFTKEEIGEYAEIIENKSKYIKELVEDLNLSTRLKN
NTLTLNKEKINLANLIKDIIIDILNDTRYENREIDFHCENDNIEINGDRILIRRAIINILFNAIVHNSEDVKIDVTLKKQ
DKISIIVEDNGRGIKGEELNRIFDRYYRGTNTGERHKGSGLGMAISKETIVAHGGDITIESELGKGTKVNILI

Sequences:

>Translated_473_residues
MKNNMKWRITGRFLVTVICVVITVVIINIVSLSGLVIYRNVTNIGMTKYDIEGIVRNFSSNIKEIDNKIYIDDKGKAILD
SKNGWIQIIDANNNEVYNYKKPSYIKNKPTAAEIVNLYKYKTSDKRNEVSTNFVAEKNIGNKRLTYIIGFGDNDITKYVI
TTRNSEVIQIIKSATIIIIIVDGIIALIFGYLFIRKLTNPLGEILLGIKKLENEEYDLYYEAKGMYNDLYYSLNNLSDRL
QENKRNRKKLDNMREEWISNISHDIKTPLASIQGYAEIIKDEDYDFTKEEIGEYAEIIENKSKYIKELVEDLNLSTRLKN
NTLTLNKEKINLANLIKDIIIDILNDTRYENREIDFHCENDNIEINGDRILIRRAIINILFNAIVHNSEDVKIDVTLKKQ
DKISIIVEDNGRGIKGEELNRIFDRYYRGTNTGERHKGSGLGMAISKETIVAHGGDITIESELGKGTKVNILI
>Mature_473_residues
MKNNMKWRITGRFLVTVICVVITVVIINIVSLSGLVIYRNVTNIGMTKYDIEGIVRNFSSNIKEIDNKIYIDDKGKAILD
SKNGWIQIIDANNNEVYNYKKPSYIKNKPTAAEIVNLYKYKTSDKRNEVSTNFVAEKNIGNKRLTYIIGFGDNDITKYVI
TTRNSEVIQIIKSATIIIIIVDGIIALIFGYLFIRKLTNPLGEILLGIKKLENEEYDLYYEAKGMYNDLYYSLNNLSDRL
QENKRNRKKLDNMREEWISNISHDIKTPLASIQGYAEIIKDEDYDFTKEEIGEYAEIIENKSKYIKELVEDLNLSTRLKN
NTLTLNKEKINLANLIKDIIIDILNDTRYENREIDFHCENDNIEINGDRILIRRAIINILFNAIVHNSEDVKIDVTLKKQ
DKISIIVEDNGRGIKGEELNRIFDRYYRGTNTGERHKGSGLGMAISKETIVAHGGDITIESELGKGTKVNILI

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=28.5087719298246, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=25.6493506493506, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=27.1255060728745, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=23.758865248227, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=23.5537190082645, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=25.9259259259259, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=421, Percent_Identity=23.5154394299287, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789149, Length=336, Percent_Identity=20.2380952380952, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=25.4385964912281, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=25.1063829787234, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789403, Length=306, Percent_Identity=24.1830065359477, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=290, Percent_Identity=23.1034482758621, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=26.2443438914027, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=25.1184834123223, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=214, Percent_Identity=28.0373831775701, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=23.8907849829352, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789808, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54359; Mature: 54359

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNMKWRITGRFLVTVICVVITVVIINIVSLSGLVIYRNVTNIGMTKYDIEGIVRNFSS
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHH
NIKEIDNKIYIDDKGKAILDSKNGWIQIIDANNNEVYNYKKPSYIKNKPTAAEIVNLYKY
HHHHHCCEEEECCCCCEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHH
KTSDKRNEVSTNFVAEKNIGNKRLTYIIGFGDNDITKYVITTRNSEVIQIIKSATIIIII
CCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHCCEEEEEE
VDGIIALIFGYLFIRKLTNPLGEILLGIKKLENEEYDLYYEAKGMYNDLYYSLNNLSDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
QENKRNRKKLDNMREEWISNISHDIKTPLASIQGYAEIIKDEDYDFTKEEIGEYAEIIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
KSKYIKELVEDLNLSTRLKNNTLTLNKEKINLANLIKDIIIDILNDTRYENREIDFHCEN
HHHHHHHHHHHCCCCEEECCCEEEEEHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECC
DNIEINGDRILIRRAIINILFNAIVHNSEDVKIDVTLKKQDKISIIVEDNGRGIKGEELN
CCEEECCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHH
RIFDRYYRGTNTGERHKGSGLGMAISKETIVAHGGDITIESELGKGTKVNILI
HHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MKNNMKWRITGRFLVTVICVVITVVIINIVSLSGLVIYRNVTNIGMTKYDIEGIVRNFSS
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHH
NIKEIDNKIYIDDKGKAILDSKNGWIQIIDANNNEVYNYKKPSYIKNKPTAAEIVNLYKY
HHHHHCCEEEECCCCCEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHH
KTSDKRNEVSTNFVAEKNIGNKRLTYIIGFGDNDITKYVITTRNSEVIQIIKSATIIIII
CCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHCCEEEEEE
VDGIIALIFGYLFIRKLTNPLGEILLGIKKLENEEYDLYYEAKGMYNDLYYSLNNLSDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
QENKRNRKKLDNMREEWISNISHDIKTPLASIQGYAEIIKDEDYDFTKEEIGEYAEIIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
KSKYIKELVEDLNLSTRLKNNTLTLNKEKINLANLIKDIIIDILNDTRYENREIDFHCEN
HHHHHHHHHHHCCCCEEECCCEEEEEHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECC
DNIEINGDRILIRRAIINILFNAIVHNSEDVKIDVTLKKQDKISIIVEDNGRGIKGEELN
CCEEECCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHH
RIFDRYYRGTNTGERHKGSGLGMAISKETIVAHGGDITIESELGKGTKVNILI
HHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]