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The map label for this gene is yvrH [H]

Identifier: 170755642

GI number: 170755642

Start: 1077623

End: 1078345

Strand: Direct

Name: yvrH [H]

Synonym: CLD_3595

Alternate gene names: 170755642

Gene position: 1077623-1078345 (Clockwise)

Preceding gene: 170755588

Following gene: 170756485

Centisome position: 27.22

GC content: 27.25

Gene sequence:

>723_bases
ATGGAGACAATATCTTTAAGTAATAAAAAAATATTAATAATTGATGACGAAGAAGATATAGTTAGATTAATAAGAACAGT
ACTTAAAAAAGAAGGATTTCAAAATATATATTATGCTACTAACTTAGAAGATGGATTTAAAGAATTTAATAAGACGGAGC
CAGATATTGTAATTTTAGATATTATGTTACCAGATGGTGAGGGGTATGAATTATGTAAAACCATAAGATCTAAATCTAAG
GTGCCTATACTATTTTTATCTGCTAAGGGTGAAGAAATAGATAAAATATTGGGATTTGCTATAGGTGGAGATGATTATAT
AACTAAACCTTTTAGCACAAAGGAGTTAGCCTATAGGGTGAAGGCTCATTTAAGAAGATATTCCTATGTGGAAAATGTTA
ACGAGGAAAAAAACATTTTATCCTTTGGACCATTTGAGCTAAATATAAGTAAAGCAGAATTTAAAAAAGATGGAGAGCTT
ATAGAATTAAAACCTAAAGAATTAGCATTAATAACTTTTTTTGCAAAGCATCCAAATCAAATAATAAGTAAAGAAAAAAT
TTGTGATAATGTTTGGGGGGAAGATTATTATGGATTTGATAATACAATAATGGTCCACATTAGAAGACTTAGAGAAAAAA
TTGAAAAAGAACCATCAAGACCAGAATATTTAATAAATGTTAAGGGATTAGGATACAAATTGGTGATAAAAAATGAAAAA
TAA

Upstream 100 bases:

>100_bases
GTTTAAAATTTTGTTATACTAAAAATAAATTTGTTATAATAAATTTAAACTCAATGAAAATTTAAATTTATATAAAATTA
AAAGAAAAAGAGGGAATAAT

Downstream 100 bases:

>100_bases
TATGAAGTGGAGAATTACAGGAAGGTTCTTAGTAACAGTTATTTGCGTAGTTATAACTGTAGTTATAATAAATATTGTAT
CTTTATCAGGTCTTGTAATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKTEPDIVILDIMLPDGEGYELCKTIRSKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENVNEEKNILSFGPFELNISKAEFKKDGEL
IELKPKELALITFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSRPEYLINVKGLGYKLVIKNEK

Sequences:

>Translated_240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKTEPDIVILDIMLPDGEGYELCKTIRSKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENVNEEKNILSFGPFELNISKAEFKKDGEL
IELKPKELALITFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSRPEYLINVKGLGYKLVIKNEK
>Mature_240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKTEPDIVILDIMLPDGEGYELCKTIRSKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENVNEEKNILSFGPFELNISKAEFKKDGEL
IELKPKELALITFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSRPEYLINVKGLGYKLVIKNEK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=35.1694915254237, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=37.4468085106383, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=31.4159292035398, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=31.7596566523605, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.3144104803493, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=31.6239316239316, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=30.3964757709251, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=32.3008849557522, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=29.646017699115, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.7017543859649, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.1688311688312, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=30.5309734513274, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=28.125, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=25.6521739130435, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=29.3233082706767, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=34.5132743362832, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27864; Mature: 27864

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKTEPDIVILD
CCCEECCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEE
IMLPDGEGYELCKTIRSKSKVPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRV
EEECCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHH
KAHLRRYSYVENVNEEKNILSFGPFELNISKAEFKKDGELIELKPKELALITFFAKHPNQ
HHHHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHCCCCCEEEECCCEEEEEEEEHHCCHH
IISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSRPEYLINVKGLGYKLVIKNEK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCC
>Mature Secondary Structure
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKTEPDIVILD
CCCEECCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEE
IMLPDGEGYELCKTIRSKSKVPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRV
EEECCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHH
KAHLRRYSYVENVNEEKNILSFGPFELNISKAEFKKDGELIELKPKELALITFFAKHPNQ
HHHHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHCCCCCEEEECCCEEEEEEEEHHCCHH
IISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSRPEYLINVKGLGYKLVIKNEK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]