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The map label for this gene is frc [H]

Identifier: 170756410

GI number: 170756410

Start: 2386633

End: 2387847

Strand: Reverse

Name: frc [H]

Synonym: CLD_2381

Alternate gene names: 170756410

Gene position: 2387847-2386633 (Counterclockwise)

Preceding gene: 170755623

Following gene: 170757665

Centisome position: 60.33

GC content: 32.51

Gene sequence:

>1215_bases
ATGACAAAAGAAGGTTTAGCTTTAGAAGGTGTAAAAGTAGTTGAATTATCAAGCTTTGTAGCGGCTCCTAGTTGTTCAAA
ATTATTAGCTGATTGGGGAGCTGATGTAATTAAAATAGAACCAATTCAAGGAGATAATATAAGAGTTGTAGGTGGAGTAT
ATAATTCACCAGCAAGAGATGATGAAAATCCTATGTTTGAACTTGAAAACGGAAATAAAAGAGGCATTGCAATAAATACT
AGAAGTGAAAAAGGTAAAGAAGTATTAGGAAAATTACTTAAAGATGCAGATGTTTTTGTTACAAATGTAAGAGAAAAAGC
ATTACAAAGAAGTGGATTATCCTATGACCAATTAAAGGATAAATATCCTTCATTAATACATGCACATATATTAGGATATG
GAGAAAAAGGACCACTTAAGGATAAGCCTGGATTTGACTATACTGCATATTTTGCAAGAGGAGCTGTAAGTACATCCTTA
ATGGAAAAAGGAACATCACCAGCTAATACTAATGCAGGCTTTGGTGATCATTATGCAGGCATGAGTTTAGCAGCTGGTAT
ATTAGCAGCACTTCACAGAAAGACATTAACTGGAAAGGGTGACAGAGTTACAGTAAGTCTATATCATACAGCTATATTTG
GTATGGGACTAATGATTACTACAGCTCAATACGGAAACAAAATGCCATTATCAAGAAGAACTCCTAATAATCCATTAGCA
ACAACCTATAGATGCAAAGATGATAGATGGATACAATTAGCATTACTTAAATATGATGCATGGTTCCCTAAATTCTGTAA
GGAAGTAATAAATAGACCTGATTTAATAGAAGATTCAAGATTTAATAAACAATCTGAAGTAGTAAAACATGTTGAAACTT
TTGTAGGAGTATTAGAAGGAGAATTTATTAAAAAGGATTTAAAGGAGTGGGCAGATTTATTAGATAAAGCTGACTTACCA
TATGAAAAATTACAATATTGTGAAGATATATTAGAAGACGAACAAGCATGGGCAAATGACTATTTATTCAAGACCACATA
TGACAGTGGAAATACTGGTGTATTAGTTAATTCACCTGTTAAATTTAGTGAAGCTGGAATGAGAACATATAAAGCTGCAC
CAAAGATCGGTGAAGACACTGAGGTAGTTCTTACATCATTAGGATACAGTAAAGAAGAAATAGAAGAAATGAGAAAAGAA
GAGTCAATAAAATAA

Upstream 100 bases:

>100_bases
TATTATTTAGCTGAATTTGGTACAAGTTTACCTTTTGTAAGTAAGGCAAGCTTAGCCATTTCAATATAGTAAAGTTTAAT
ATTTAAGGAGGAATGTTAAA

Downstream 100 bases:

>100_bases
ATTAGTGTAAGTTTTTAAATGGAGGGTATAAAAACTTAGATCGAGAAGGGGGAGGAATATAAATGGCTGATAAGAAAGAG
GTCAAAAAGAATGCAGCAAA

Product: putative hydroxyacyl-CoA:R-2-hydroxyglutaryl-CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINT
RSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGVLEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK

Sequences:

>Translated_404_residues
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINT
RSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGVLEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK
>Mature_403_residues
TKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINTR
SEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLM
EKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLAT
TYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGVLEGEFIKKDLKEWADLLDKADLPY
EKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEE
SIK

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=394, Percent_Identity=25.3807106598985, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI300863124, Length=331, Percent_Identity=26.5861027190332, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI266456254, Length=410, Percent_Identity=25.3658536585366, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI42794625, Length=410, Percent_Identity=25.3658536585366, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI300863126, Length=392, Percent_Identity=23.7244897959184, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI266458393, Length=318, Percent_Identity=24.8427672955975, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI266458397, Length=275, Percent_Identity=26.9090909090909, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788717, Length=423, Percent_Identity=29.3144208037825, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082093, Length=363, Percent_Identity=24.2424242424242, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786222, Length=403, Percent_Identity=23.8213399503722, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115535051, Length=322, Percent_Identity=25.4658385093168, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=320, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648431, Length=413, Percent_Identity=27.8450363196126, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585488, Length=376, Percent_Identity=27.3936170212766, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44982; Mature: 44850

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARD
CCCCCCEECCEEEEEHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGIAINTRSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
MSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGVLEG
EEEEECCCCEEEEEEEHHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCC
KFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARD
CCCCCEECCEEEEEHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGIAINTRSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
MSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGVLEG
EEEEECCCCEEEEEEEHHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCC
KFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]