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The map label for this gene is yvyE [H]

Identifier: 170756142

GI number: 170756142

Start: 3317984

End: 3318634

Strand: Reverse

Name: yvyE [H]

Synonym: CLD_1466

Alternate gene names: 170756142

Gene position: 3318634-3317984 (Counterclockwise)

Preceding gene: 170754780

Following gene: 170757190

Centisome position: 83.84

GC content: 28.88

Gene sequence:

>651_bases
ATGTCATATTTTACCATAAAAAACTTTGGAAAAGATGAATTCGAAGAAAAAAAGTCTACTTTTATAGGAAGAGCAAAAAG
AGTTTATACAGAAGAAGAAGCTAAAGATTTTATAAATAAAGTTAAAGGGGAAGAAAAAGAAGCAAGACATAATGTATATG
CATATGTTATTGGAGAAAACATGGGAATACAGAGATATAGTGATGATGGTGAGCCACAAGGAACAGGTGGTATACCAGTA
TTAGATGTTATAAAAAAGAATGAAGTTACAGATATAGCTATAGTAGTCACAAGGTATTTTGGGGGAATACTTTTAGGTAA
AGGTGGACTAGTAAGGGCTTATTCAAAAGGAGCTGCTGTATCTATAAAGAATGCAGGTATAGTTGAAAAAGTTAAAGGTA
AATCTCTTACTTTCATAGTAGAATATGATGCTTTAGGCAAAATACAGTATTTGTTTGAACAAAATCTTTGGCATATAGAA
AATATAGAATATACAGAAAAAGTTAGTTTAACTATGTTTTGTGAAATAAATATTATATCTACAATAGAAAAGAAAGTTCT
AGAGATAACTAACGGAAATTGTAAAATAATTAAGGGAGATGAAAATTTCTACTTTAAAATGGATAATAGGCTATTTGGAG
ATGAGCAATAA

Upstream 100 bases:

>100_bases
TATATATATAAAAAATAAAACTGATAAAGATTATATATTAAAAGCAGTAGATGAATATTTACAAGAAATAGATGACCCTA
TATAGAAAAGAGGTATACTT

Downstream 100 bases:

>100_bases
ATTTGAATTTTTAACTTTCTCTATGATATAATAATTTAGTGAATTTGCATTTAAATATTAGTATTTTCAATTATAAATAT
ACTAATAAAAATAGTTTTAA

Product: hypothetical protein

Products: dihydrofolate; dTMP

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPV
LDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVSIKNAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIE
NIEYTEKVSLTMFCEINIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFGDEQ

Sequences:

>Translated_216_residues
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPV
LDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVSIKNAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIE
NIEYTEKVSLTMFCEINIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFGDEQ
>Mature_215_residues
SYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPVL
DVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVSIKNAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIEN
IEYTEKVSLTMFCEINIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFGDEQ

Specific function: Unknown

COG id: COG1739

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IMPACT family [H]

Homologues:

Organism=Escherichia coli, GI87082338, Length=189, Percent_Identity=34.3915343915344, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR020568
- InterPro:   IPR000640
- InterPro:   IPR015796
- InterPro:   IPR015269
- InterPro:   IPR020569
- InterPro:   IPR001498 [H]

Pfam domain/function: PF09186 DUF1949; PF01205 UPF0029 [H]

EC number: 2.1.1.45

Molecular weight: Translated: 24530; Mature: 24399

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00910 UPF0029

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGEN
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECC
MGIQRYSDDGEPQGTGGIPVLDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAV
CCCEEECCCCCCCCCCCCCCEEEECCCCCCHHEEEEEHHHCEEEECCCCEEEEECCCCEE
SIKNAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIENIEYTEKVSLTMFCEINIIS
EECCCCCEEECCCCEEEEEEEECCCCHHHEEHHCCCEEECCCCCCCEEEEEEEEEEEEHH
TIEKKVLEITNGNCKIIKGDENFYFKMDNRLFGDEQ
HHHHHHEEEECCCEEEEECCCCEEEEECCEECCCCC
>Mature Secondary Structure 
SYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGEN
CEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECC
MGIQRYSDDGEPQGTGGIPVLDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAV
CCCEEECCCCCCCCCCCCCCEEEECCCCCCHHEEEEEHHHCEEEECCCCEEEEECCCCEE
SIKNAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIENIEYTEKVSLTMFCEINIIS
EECCCCCEEECCCCEEEEEEEECCCCHHHEEHHCCCEEECCCCCCCEEEEEEEEEEEEHH
TIEKKVLEITNGNCKIIKGDENFYFKMDNRLFGDEQ
HHHHHHEEEECCCEEEEECCCCEEEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydrofolate; dUMP

Specific reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 3141378; 8313894 [H]