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The map label for this gene is hcrA [H]

Identifier: 170755658

GI number: 170755658

Start: 3052462

End: 3054792

Strand: Reverse

Name: hcrA [H]

Synonym: CLD_1718

Alternate gene names: 170755658

Gene position: 3054792-3052462 (Counterclockwise)

Preceding gene: 170757789

Following gene: 170756969

Centisome position: 77.18

GC content: 36.51

Gene sequence:

>2331_bases
TTGAGTAATACAATTGGGGTAAGCATACCAAGAAAAGAGGCTTTTGATAAAGTTACAGGTACAGCAAAATATACTGATGA
TACACTTCTTCCTGGCACTTTGCATGCTAAAATGCTCACAAGTCGTTATGCACATGCAAAGATTAAATCACTTGATATAG
CTGAAGCTAAGAAAGCATTAGGTGTTCAAGCAGTAATAACAGGTGATTATCTTCCTATACTTTCTGGATCAGTAATAGAA
GATAGACCCCCAATAGCGAGAGATAGAGTACGTTACTTTGGAGAACCTGTTGCAGTAGTAATTGCAAATAGTGAGCAAGA
AGCAATGAAAGCTGTAAAGCTAATAAATGTAGAATATGAACCATTACCTGTTGTTAATTCAATAAGTGATTCTTTGAAGC
CAGGTGCTACTCTTATACATGAAAATTTAGGGCAGTATAATCATGCGGTAAATGATGTATATCCTGAACTAAATACTAAT
ATTTTAGATCGAATAAAAATAAGAAAAGGTGATATGGGAAAGGGTTGGGCAGAAAGCGAAGTTATAGTAGAAGGAAATTT
TTCACTTCCACAATCAGATCATCTTGCAATGGAAACTAGAAGTGCGAAAGCTCAAATTATGCCAGACGGAAAAATAATAA
TTTATACTTCTTCACAAGGGCCTTATTCTGTTAAGAGGCGTTTAAGTAAGATTTATAATATACCAGAAGGAAATATAGTT
GTTAAAGTACCATTTGTAGGTGGAGGATTTGGCGGCAAGGCAGCTACTCAATTGGAATTTATTGCATACCTGGCTTCCAA
GGCTGTTAATGGTAGATTAGTTACTATAACCAATTCAAGAGAAGAGGATATTAAAACTTCACCCTGTAGAATTGGAGTTG
AGGGAAATTTAAAAATAGGTGCAACAAAAGATGGAATTATTAAAGTACTTGAAGCTAAATATGCGGTTGATAGCGGAGCT
TATGCAGACACTGGTCCACGTATGGCTAAGGCTATGGCAATAGATTGTTCTGGCCCATATAATATTGAAAATATATGGTG
TGATTCAATATGTGTTTATACTAATCATACCTATGTTACTTCTTATCGTGGATTTGGTCATACAGAGTATACCTTTTGCA
TGGAGAGAATGATGGATAAGTTGGCAACAAAGCTTGGTATGGATCCTCTAGAATTAAGAATTAACAATGCTATGAAACCC
GGACAATACACCCCAACACAAGTAAAAACAACTTTAAGTAATATAGGCAAATTGGAAGATTGCTTGACAAAATTAAAGGA
GTTAGCTAAATGGGATGAAGGACAGGTAATAAAAACAGGAGACGGTATGATAAAGGCAAAGGGAATGGGCTGCTTTTGGA
AAACATCTGATTCGCCTGCGGATGCTGTTTCTGGAGCTTTTCTTACTTTCAATACAGATGGAAGCATAAATCTTAATACT
GGTGCAGTCGAAATTGGACCGTCTACAAAGACTACTTTAGCCCAAATACTTGCTGAGAAATTGAAAATGGATGTAAGTAG
AATTCATGTAGTGATGGGAGTGGATACTCAAGTTTCACCAGAACATTGGAAAACAGTTGCAAGTATGACAACTTTTATGG
CAGGCAGGGCAGTTCTTAGAGCTGCTGAAGATCTTATAAGGCAGCTGAAAAGTTTAGCAGCTACTGTTATGAAATCTCCA
CCAGAAGATTTAGAAGTTGCAGAAGAAAAGGTATATTTAAGACAAGATCCAGAAATATATGTTTCATTCAAGGATTTAGC
TAGAGGTTATAAAGAGTTTAATGGTCTCGCAATTGACGGACAAATACTTGCACGTGGGACCTTTATAATGAGTCATATTA
CTAATATGGATAAAGAAACAGGAAAAGGTAAACCCGGACCAGCGTGGACTGTAGGTGCTCAAGCAGTTGAGATTGAATAT
GATCCTAATAAGTTCACATATAGACTTTTAAAAGCAATTACTGTTGTAGATGCAGGTAAAGTTATTAATCCCAAAACCTC
AAAAGGATTAATAATGGGAGGTATGAATATTGGACTTGGTATAGCTACTAGAGAAGCTTTTACATATGATAGGAACGCTA
GGCTACAGACCACTACATTGAGAACTTATAAGTTAATGAGATTCGGAGAAAATCCAGAATACGCGGTTGATTTCGTTGAA
ACTCCCCAAATTGATGCACCTTTCGGAGCTCGTGGATTTGCAGAACATGGAATAATAGCAATTCCAGCTACATTCGCAAA
TGCTATATCACATGCAGCTGGGCATGAATTTGATAAACTACCTATAACACCTGAAATAATTTGGAATGCTAAGACTGGAG
GGAAAATATGA

Upstream 100 bases:

>100_bases
TATATTGAATAAATTACCGAAAAGCAGGTAAAAATAAAATTAATTTAAAAATTACATAAGTTAATTTTTTAGTCCTGTTT
TTAGAAGGAGGTAAGAGCAT

Downstream 100 bases:

>100_bases
TACCCTTTGATTTTGAATATTATAAACCTGAAACTATTGAAGAGGCAGTTCAATTATATGCTAAATTAAATGCTAGAGGA
AAAAAGCCCTTATATTTCGG

Product: xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MSNTIGVSIPRKEAFDKVTGTAKYTDDTLLPGTLHAKMLTSRYAHAKIKSLDIAEAKKALGVQAVITGDYLPILSGSVIE
DRPPIARDRVRYFGEPVAVVIANSEQEAMKAVKLINVEYEPLPVVNSISDSLKPGATLIHENLGQYNHAVNDVYPELNTN
ILDRIKIRKGDMGKGWAESEVIVEGNFSLPQSDHLAMETRSAKAQIMPDGKIIIYTSSQGPYSVKRRLSKIYNIPEGNIV
VKVPFVGGGFGGKAATQLEFIAYLASKAVNGRLVTITNSREEDIKTSPCRIGVEGNLKIGATKDGIIKVLEAKYAVDSGA
YADTGPRMAKAMAIDCSGPYNIENIWCDSICVYTNHTYVTSYRGFGHTEYTFCMERMMDKLATKLGMDPLELRINNAMKP
GQYTPTQVKTTLSNIGKLEDCLTKLKELAKWDEGQVIKTGDGMIKAKGMGCFWKTSDSPADAVSGAFLTFNTDGSINLNT
GAVEIGPSTKTTLAQILAEKLKMDVSRIHVVMGVDTQVSPEHWKTVASMTTFMAGRAVLRAAEDLIRQLKSLAATVMKSP
PEDLEVAEEKVYLRQDPEIYVSFKDLARGYKEFNGLAIDGQILARGTFIMSHITNMDKETGKGKPGPAWTVGAQAVEIEY
DPNKFTYRLLKAITVVDAGKVINPKTSKGLIMGGMNIGLGIATREAFTYDRNARLQTTTLRTYKLMRFGENPEYAVDFVE
TPQIDAPFGARGFAEHGIIAIPATFANAISHAAGHEFDKLPITPEIIWNAKTGGKI

Sequences:

>Translated_776_residues
MSNTIGVSIPRKEAFDKVTGTAKYTDDTLLPGTLHAKMLTSRYAHAKIKSLDIAEAKKALGVQAVITGDYLPILSGSVIE
DRPPIARDRVRYFGEPVAVVIANSEQEAMKAVKLINVEYEPLPVVNSISDSLKPGATLIHENLGQYNHAVNDVYPELNTN
ILDRIKIRKGDMGKGWAESEVIVEGNFSLPQSDHLAMETRSAKAQIMPDGKIIIYTSSQGPYSVKRRLSKIYNIPEGNIV
VKVPFVGGGFGGKAATQLEFIAYLASKAVNGRLVTITNSREEDIKTSPCRIGVEGNLKIGATKDGIIKVLEAKYAVDSGA
YADTGPRMAKAMAIDCSGPYNIENIWCDSICVYTNHTYVTSYRGFGHTEYTFCMERMMDKLATKLGMDPLELRINNAMKP
GQYTPTQVKTTLSNIGKLEDCLTKLKELAKWDEGQVIKTGDGMIKAKGMGCFWKTSDSPADAVSGAFLTFNTDGSINLNT
GAVEIGPSTKTTLAQILAEKLKMDVSRIHVVMGVDTQVSPEHWKTVASMTTFMAGRAVLRAAEDLIRQLKSLAATVMKSP
PEDLEVAEEKVYLRQDPEIYVSFKDLARGYKEFNGLAIDGQILARGTFIMSHITNMDKETGKGKPGPAWTVGAQAVEIEY
DPNKFTYRLLKAITVVDAGKVINPKTSKGLIMGGMNIGLGIATREAFTYDRNARLQTTTLRTYKLMRFGENPEYAVDFVE
TPQIDAPFGARGFAEHGIIAIPATFANAISHAAGHEFDKLPITPEIIWNAKTGGKI
>Mature_775_residues
SNTIGVSIPRKEAFDKVTGTAKYTDDTLLPGTLHAKMLTSRYAHAKIKSLDIAEAKKALGVQAVITGDYLPILSGSVIED
RPPIARDRVRYFGEPVAVVIANSEQEAMKAVKLINVEYEPLPVVNSISDSLKPGATLIHENLGQYNHAVNDVYPELNTNI
LDRIKIRKGDMGKGWAESEVIVEGNFSLPQSDHLAMETRSAKAQIMPDGKIIIYTSSQGPYSVKRRLSKIYNIPEGNIVV
KVPFVGGGFGGKAATQLEFIAYLASKAVNGRLVTITNSREEDIKTSPCRIGVEGNLKIGATKDGIIKVLEAKYAVDSGAY
ADTGPRMAKAMAIDCSGPYNIENIWCDSICVYTNHTYVTSYRGFGHTEYTFCMERMMDKLATKLGMDPLELRINNAMKPG
QYTPTQVKTTLSNIGKLEDCLTKLKELAKWDEGQVIKTGDGMIKAKGMGCFWKTSDSPADAVSGAFLTFNTDGSINLNTG
AVEIGPSTKTTLAQILAEKLKMDVSRIHVVMGVDTQVSPEHWKTVASMTTFMAGRAVLRAAEDLIRQLKSLAATVMKSPP
EDLEVAEEKVYLRQDPEIYVSFKDLARGYKEFNGLAIDGQILARGTFIMSHITNMDKETGKGKPGPAWTVGAQAVEIEYD
PNKFTYRLLKAITVVDAGKVINPKTSKGLIMGGMNIGLGIATREAFTYDRNARLQTTTLRTYKLMRFGENPEYAVDFVET
PQIDAPFGARGFAEHGIIAIPATFANAISHAAGHEFDKLPITPEIIWNAKTGGKI

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To xanthine oxidases [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=799, Percent_Identity=26.9086357947434, Blast_Score=214, Evalue=3e-55,
Organism=Homo sapiens, GI71773480, Length=765, Percent_Identity=25.4901960784314, Blast_Score=196, Evalue=6e-50,
Organism=Escherichia coli, GI1789230, Length=777, Percent_Identity=28.1853281853282, Blast_Score=289, Evalue=4e-79,
Organism=Escherichia coli, GI1789246, Length=816, Percent_Identity=27.2058823529412, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI1786478, Length=762, Percent_Identity=22.3097112860892, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=682, Percent_Identity=25.9530791788856, Blast_Score=165, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17539860, Length=761, Percent_Identity=23.6530880420499, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=753, Percent_Identity=23.1075697211155, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737937, Length=773, Percent_Identity=24.9676584734799, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24647193, Length=714, Percent_Identity=21.4285714285714, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017607
- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 84736; Mature: 84605

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTIGVSIPRKEAFDKVTGTAKYTDDTLLPGTLHAKMLTSRYAHAKIKSLDIAEAKKAL
CCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GVQAVITGDYLPILSGSVIEDRPPIARDRVRYFGEPVAVVIANSEQEAMKAVKLINVEYE
CEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHEECCCC
PLPVVNSISDSLKPGATLIHENLGQYNHAVNDVYPELNTNILDRIKIRKGDMGKGWAESE
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCCCCCCE
VIVEGNFSLPQSDHLAMETRSAKAQIMPDGKIIIYTSSQGPYSVKRRLSKIYNIPEGNIV
EEEECCCCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEE
VKVPFVGGGFGGKAATQLEFIAYLASKAVNGRLVTITNSREEDIKTSPCRIGVEGNLKIG
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEC
ATKDGIIKVLEAKYAVDSGAYADTGPRMAKAMAIDCSGPYNIENIWCDSICVYTNHTYVT
CCCCHHHHHHHHHHHCCCCCCCCCCCHHEEEEEEECCCCCCCCEEEECCEEEEECCEEEE
SYRGFGHTEYTFCMERMMDKLATKLGMDPLELRINNAMKPGQYTPTQVKTTLSNIGKLED
EECCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
CLTKLKELAKWDEGQVIKTGDGMIKAKGMGCFWKTSDSPADAVSGAFLTFNTDGSINLNT
HHHHHHHHHCCCCCCEEECCCCEEEECCCEEEEECCCCCHHHHCCEEEEEECCCCEEECC
GAVEIGPSTKTTLAQILAEKLKMDVSRIHVVMGVDTQVSPEHWKTVASMTTFMAGRAVLR
CEEEECCCCHHHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEDLIRQLKSLAATVMKSPPEDLEVAEEKVYLRQDPEIYVSFKDLARGYKEFNGLAIDG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCEEEEEHHHHHHHHHHHCCEEECC
QILARGTFIMSHITNMDKETGKGKPGPAWTVGAQAVEIEYDPNKFTYRLLKAITVVDAGK
EEEEHHHHHHHHHHCCCHHCCCCCCCCCEEECCEEEEEEECCCHHHHHHHHHHHHCCCCC
VINPKTSKGLIMGGMNIGLGIATREAFTYDRNARLQTTTLRTYKLMRFGENPEYAVDFVE
EECCCCCCCEEEECCCCCCEEEECHHEEECCCCEEEEEHHHHEEEECCCCCCCEEEEEEC
TPQIDAPFGARGFAEHGIIAIPATFANAISHAAGHEFDKLPITPEIIWNAKTGGKI
CCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCC
>Mature Secondary Structure 
SNTIGVSIPRKEAFDKVTGTAKYTDDTLLPGTLHAKMLTSRYAHAKIKSLDIAEAKKAL
CCCEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GVQAVITGDYLPILSGSVIEDRPPIARDRVRYFGEPVAVVIANSEQEAMKAVKLINVEYE
CEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHEECCCC
PLPVVNSISDSLKPGATLIHENLGQYNHAVNDVYPELNTNILDRIKIRKGDMGKGWAESE
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCCCCCCE
VIVEGNFSLPQSDHLAMETRSAKAQIMPDGKIIIYTSSQGPYSVKRRLSKIYNIPEGNIV
EEEECCCCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEE
VKVPFVGGGFGGKAATQLEFIAYLASKAVNGRLVTITNSREEDIKTSPCRIGVEGNLKIG
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEC
ATKDGIIKVLEAKYAVDSGAYADTGPRMAKAMAIDCSGPYNIENIWCDSICVYTNHTYVT
CCCCHHHHHHHHHHHCCCCCCCCCCCHHEEEEEEECCCCCCCCEEEECCEEEEECCEEEE
SYRGFGHTEYTFCMERMMDKLATKLGMDPLELRINNAMKPGQYTPTQVKTTLSNIGKLED
EECCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
CLTKLKELAKWDEGQVIKTGDGMIKAKGMGCFWKTSDSPADAVSGAFLTFNTDGSINLNT
HHHHHHHHHCCCCCCEEECCCCEEEECCCEEEEECCCCCHHHHCCEEEEEECCCCEEECC
GAVEIGPSTKTTLAQILAEKLKMDVSRIHVVMGVDTQVSPEHWKTVASMTTFMAGRAVLR
CEEEECCCCHHHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEDLIRQLKSLAATVMKSPPEDLEVAEEKVYLRQDPEIYVSFKDLARGYKEFNGLAIDG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCEEEEEHHHHHHHHHHHCCEEECC
QILARGTFIMSHITNMDKETGKGKPGPAWTVGAQAVEIEYDPNKFTYRLLKAITVVDAGK
EEEEHHHHHHHHHHCCCHHCCCCCCCCCEEECCEEEEEEECCCHHHHHHHHHHHHCCCCC
VINPKTSKGLIMGGMNIGLGIATREAFTYDRNARLQTTTLRTYKLMRFGENPEYAVDFVE
EECCCCCCCEEEECCCCCCEEEECHHEEECCCCEEEEEHHHHEEEECCCCCCCEEEEEEC
TPQIDAPFGARGFAEHGIIAIPATFANAISHAAGHEFDKLPITPEIIWNAKTGGKI
CCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]