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The map label for this gene is etfA [H]

Identifier: 170755641

GI number: 170755641

Start: 3474094

End: 3475101

Strand: Reverse

Name: etfA [H]

Synonym: CLD_1334

Alternate gene names: 170755641

Gene position: 3475101-3474094 (Counterclockwise)

Preceding gene: 170754881

Following gene: 170756965

Centisome position: 87.79

GC content: 30.56

Gene sequence:

>1008_bases
ATGATGAATTTATCAGATTTTAAAGGCATATGGGTTTTTGCAGAACAGAGAGAAGGAAAGCTTCAAAAAGTAGCTTTAGA
GTTAATAGGTCAAGGTAAAGAGTTATCTAAAAAATTAGGAGTAGAATTGACTGCTGTTTTATTAGGTTATGATATTGATG
ATATACCAAGGCAATTAATAAGTTATGGTGCAGATAAGGTATTGTATGTAAATAATCCTTTATTAAAAAATTATAATACA
GATGGATACACAAAAGTTATATATGATTTAATACAAGAAAGAAAACCTGAAATATTATTAGTCGGAGCTACTTATATAGG
AAGAGATTTAGCACCTAGAATTTCATCAAGATTAGGGACAGGACTTACAGCGGATTGTACAGGATTGGATATAGATAATA
ATACAAGGAATCTTTTAATGACAAGGCCTGCTTTTGGTGGTAATTTAATGGCTACAATAATTTGTGACAGCAATAGACCT
CAAATGTCTACAGTAAGGCCAGGCGTTTTTGGAAAATTAGAAAAAGATGCTAATAGAGATGGAAGTATTGAAAATATAAA
AGTAAATTTAAAAGAATCAGATATAAAAATAAAAATAAAAGAAATTGTTAAATTAGCAAAAGAAATAGAAGATATAAGTG
AAGCAAAAATATTGGTTTCAGGTGGAAGAGGACTTGGAAGCCCAGAAGGATTTAAATTATTAAGAGAATTGGCTGATTTA
ATGGGAGGAGCTATATCAGGTTCTCGTGCAGTTGTAGATAGTGGATGGATAGATAAAGCTTATCAGGTTGGACAAACAGG
AAAAACAGTTAGACCTAATTTATATATAGCTTGTGGAATATCAGGAGCTATTCAGCATCTAGCAGGAATGCAAGACAGTG
ACTATATTATAGCTATAAATAAAGATGAATCAGCACCAATAATGCAAGTAGCCGATTTATCTATAGTAGGAGATTACAAA
AAAATATTACCTTCTATGATAGATGAAATAAAAAAGATCAATAATTAG

Upstream 100 bases:

>100_bases
AAAAAGAGAAGGTGTTTTAATAAATAAGCCTTTTAAAGAAGCAGCACAATATGCAGTAGAAAAATTAAAAGAAAAACACT
ATATTTAGGTTGGGGGAGAT

Downstream 100 bases:

>100_bases
ATAAAATAGTAATAGTTACTTTAAAATTTGATTATAAAATATATTGTAATCATATAAAAAAAGAATGTGAAATATAAATA
ATATATCACATTCTTTTTTT

Product: electron transfer flavoprotein, alpha subunit/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MMNLSDFKGIWVFAEQREGKLQKVALELIGQGKELSKKLGVELTAVLLGYDIDDIPRQLISYGADKVLYVNNPLLKNYNT
DGYTKVIYDLIQERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDNNTRNLLMTRPAFGGNLMATIICDSNRP
QMSTVRPGVFGKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADL
MGGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYK
KILPSMIDEIKKINN

Sequences:

>Translated_335_residues
MMNLSDFKGIWVFAEQREGKLQKVALELIGQGKELSKKLGVELTAVLLGYDIDDIPRQLISYGADKVLYVNNPLLKNYNT
DGYTKVIYDLIQERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDNNTRNLLMTRPAFGGNLMATIICDSNRP
QMSTVRPGVFGKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADL
MGGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYK
KILPSMIDEIKKINN
>Mature_335_residues
MMNLSDFKGIWVFAEQREGKLQKVALELIGQGKELSKKLGVELTAVLLGYDIDDIPRQLISYGADKVLYVNNPLLKNYNT
DGYTKVIYDLIQERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDNNTRNLLMTRPAFGGNLMATIICDSNRP
QMSTVRPGVFGKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADL
MGGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYK
KILPSMIDEIKKINN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=334, Percent_Identity=36.2275449101796, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=39.1941391941392, Blast_Score=167, Evalue=9e-42,
Organism=Escherichia coli, GI1787990, Length=334, Percent_Identity=29.3413173652695, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786226, Length=334, Percent_Identity=29.3413173652695, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082157, Length=243, Percent_Identity=25.5144032921811, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=332, Percent_Identity=36.144578313253, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6325261, Length=301, Percent_Identity=32.5581395348837, Blast_Score=152, Evalue=6e-38,
Organism=Drosophila melanogaster, GI17136898, Length=321, Percent_Identity=34.2679127725857, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24652801, Length=321, Percent_Identity=34.2679127725857, Blast_Score=164, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36633; Mature: 36633

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNLSDFKGIWVFAEQREGKLQKVALELIGQGKELSKKLGVELTAVLLGYDIDDIPRQLI
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCEEEEHEECCCHHHHHHHHH
SYGADKVLYVNNPLLKNYNTDGYTKVIYDLIQERKPEILLVGATYIGRDLAPRISSRLGT
HCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHCCHHHHHHHHHHCC
GLTADCTGLDIDNNTRNLLMTRPAFGGNLMATIICDSNRPQMSTVRPGVFGKLEKDANRD
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADL
CCEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHH
MGGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAIN
HCCCCCCCCEEEECCCCHHHHHCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEEEEC
KDESAPIMQVADLSIVGDYKKILPSMIDEIKKINN
CCCCCCEEEEECEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMNLSDFKGIWVFAEQREGKLQKVALELIGQGKELSKKLGVELTAVLLGYDIDDIPRQLI
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCEEEEHEECCCHHHHHHHHH
SYGADKVLYVNNPLLKNYNTDGYTKVIYDLIQERKPEILLVGATYIGRDLAPRISSRLGT
HCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHCCHHHHHHHHHHCC
GLTADCTGLDIDNNTRNLLMTRPAFGGNLMATIICDSNRPQMSTVRPGVFGKLEKDANRD
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADL
CCEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHH
MGGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAIN
HCCCCCCCCEEEECCCCHHHHHCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEEEEC
KDESAPIMQVADLSIVGDYKKILPSMIDEIKKINN
CCCCCCEEEEECEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]