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The map label for this gene is dctR [H]

Identifier: 170755347

GI number: 170755347

Start: 312081

End: 312755

Strand: Direct

Name: dctR [H]

Synonym: CLD_0515

Alternate gene names: 170755347

Gene position: 312081-312755 (Clockwise)

Preceding gene: 170756137

Following gene: 170757067

Centisome position: 7.88

GC content: 26.81

Gene sequence:

>675_bases
TTGATTCGGGTAATGATAGTTGAAGATGATCCTATGGTTAGAGAAATAAATTCTAAATTTTTAAAAAGAGTAGAAGGATT
TGTTTTGTATAAAGCAGTTTCCAATCTTTATGACGCTAAAAAATTTATAGCCATGAAAAAGCCAGATCTTATATTACTTG
ATGTATATCTTCCTAAAGAAAATGGTATTGATCTTTTGAAGTGGATAAGAAAGCAAGATATAGACATAGATATTATCTTA
ATTACAGCAGATAAATCTATTGAAAGAATACAGGAAGCCTTTAGGGGTGGAGTTGTAGATTATCTTATAAAACCCTTTAA
CTTCGAAAGATTTAAAGAATCACTTATTCAATTTAAAGGTAGATATTACGAATTTAAAAAAAATAATGTAATTGAACAAA
AAGATTTAGATAAAATAATATGTAGTTCTAATATATCTCAAAATGAAGATGACTTTGCTAAAGGGCTTAATAAATACACT
TATAAATCTATATGGAATGAAATAGAAAAAAGTAATGATAAGGATTTTACAGCAGAGTACTTAGCAGAAAAACTAGGAAT
AGCCAGAGTAACAGTTAGAAGATATCTTGAATATATGGAAAAAGAAAATAAAGTAGATAAATTAGTGGAATATGGGAAGG
TAGGTAGACCACAACATAAATATCACAAAATTTAA

Upstream 100 bases:

>100_bases
GTAAAAAAAATAATTGATGAGACTAAAGGAACAATAAGACTTGATGTGGACAACGGTGTTATTTGGAATATAACTATACC
GATGACAAGGGGTGATAAAA

Downstream 100 bases:

>100_bases
TAAAAATAAAATAATTGGTGTAAAAGATGATGAAGAATTATTAGTTAGGGGTATTAACAATATTTTAAAGTATTTAAAAA
ATGGAGTAGTTATTACATAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MIRVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRGGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVDKLVEYGKVGRPQHKYHKI

Sequences:

>Translated_224_residues
MIRVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRGGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVDKLVEYGKVGRPQHKYHKI
>Mature_224_residues
MIRVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRGGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVDKLVEYGKVGRPQHKYHKI

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790566, Length=226, Percent_Identity=35.3982300884956, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786838, Length=222, Percent_Identity=33.7837837837838, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=34.8623853211009, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26613; Mature: 26613

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGIDLLKWIRKQDIDIDIILITADKSIERIQEAFRGGVVDYLIKPFNFERFKESLIQFKG
CCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHC
RYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYTYKSIWNEIEKSNDKDFTAEY
HHEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAEKLGIARVTVRRYLEYMEKENKVDKLVEYGKVGRPQHKYHKI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MIRVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGIDLLKWIRKQDIDIDIILITADKSIERIQEAFRGGVVDYLIKPFNFERFKESLIQFKG
CCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHC
RYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYTYKSIWNEIEKSNDKDFTAEY
HHEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAEKLGIARVTVRRYLEYMEKENKVDKLVEYGKVGRPQHKYHKI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]